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Amevan (Metronidazole)
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Amevan

Flagyl is an oral antiprotozoal and antibacterial. It is thought to work by entering the bacterial cell, acting on some components of the cell, and destroying the bacteria. Treating certain infections caused by bacteria or amoebas. It may also be used for other conditions as determined by your doctor.

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Amebidal, Amobin, Anaerobex, Anerobia, Bemetrazole, Birodogyl, Clont, Corsagyl, Efloran, Emedal, Etronil, Fladystin, Flagenase, Flagicure, Flagystatin, Flanizol, Florazole, Gynotran, Klont, Litagyl, Mecozol, Metco, Metrogel, Metrogyl, Metronidazole, Metrosa, Metrozine, Micogyl, Nidagyl, Patryl, Robaz, Rodogyl, Rozacrme, Rozex, Trogyl, Vagilen, Wingyl

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Also known as: Metronidazole

Description

Amevan (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Amevan is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.

Dosage

Pregnant patients should not be treated during the first trimester. In pregnant patients in whom alternative treatment has been inadequate, the one-day course of therapy should not be used, as it results in higher serum levels which can reach the fetal circulation

Overdose

Single oral doses of Amevan, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Amevan has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Amevan overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.

Storage

Store below 77 degrees F (25 degrees C) and protect from light.

Side effects

The most common side effects associated with Amevan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Hypersensitivity. Amevan Tablets is contraindicated in patients with a prior history of hypersensitivity to metronidazole or other nitroimidazole derivatives. In patients with trichomoniasis, Amevan Tablets is contraindicated during the first trimester of pregnancy.

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