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Amrizole (Metronidazole)
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Amrizole

Amrizole is an antibiotic and antiprotozoal medication. It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis.

Other names for this medication:
Aldezol, Amebidal, Amobin, Amotein, Anaeromet, Asuzol, Clont, Colpofilin, Deprocid, Dirozyl, Etron, Farnat, Giardyl, Ginkan, Gynotran, Lindoplus, Mecozol, Medazol, Metrolag, Metronex, Metrozole, Missilor, Molazol, Monizole, Nipazol, Novazole, Onida, Orogyl, Riazole, Rodogyl, Rupezol, Trichazole, Unigyl, Vandazole, Varizil, Wingyl

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Duricef, Myambutol, Sumycin, Biaxin, Keflex, Zithromax

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Also known as: Metronidazole

Description

Amrizole (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Amrizole is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.

Dosage

Pregnant patients should not be treated during the first trimester. In pregnant patients in whom alternative treatment has been inadequate, the one-day course of therapy should not be used, as it results in higher serum levels which can reach the fetal circulation

Overdose

In cases of overdose in adults, the clinical symptoms are usually limited to nausea, vomiting, ataxia and slight disorientation. In a preterm newborn, no clinical or biological sign of toxicity developed.

There is no specific treatment for Amrizole overdose, Amrizole infusion should be discontinued. Patients should be treated symptomatically.

Storage

Store below 77 degrees F (25 degrees C) and protect from light.

Side effects

The most common side effects associated with Amrizole are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Metronidazole should be used with caution in patients with active disease of the Central Nervous System. The treatment should be withdrawn in case of ataxia, dizziness, or confusion. The risk of aggravation of the neurological state should be considered in patients suffering from severe central and peripheral neurological diseases, fixed or progressive paraesthesia and epilepsy. Caution is required in patients with active disease of the central nervous system except for brain abscess.

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