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Anazol (Metronidazole)
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Anazol

Anazol belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

Other names for this medication:
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Also known as: Metronidazole

Description

Anazol (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Anazol is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.

Dosage

In the Female. One-day treatment – two grams of Anazol, given either as a single dose or in two divided doses of one gram each, given in the same day. Seven-day course of treatment – 250 mg three times daily for seven consecutive days. There is some indication from controlled comparative studies that cure rates as determined by vaginal smears and signs and symptoms, may be higher after a seven-day course of treatment than after a one-day treatment regimen.

The dosage regimen should be individualized. Single-dose treatment can assure compliance, especially if administered under supervision, in those patients who cannot be relied on to continue the seven-day regimen. A seven-day course of treatment may minimize reinfection by protecting the patient long enough for the sexual contacts to obtain appropriate treatment. Further, some patients may tolerate one treatment regimen better than the other.

Pregnant patients should not be treated during the first trimester In pregnant patients for whom alternative treatment has been inadequate, the one-day course of therapy should not be used, as it results in higher serum levels which can reach the fetal circulation.

When repeat courses of the drug are required, it is recommended that an interval of four to six weeks elapse between courses and that the presence of the trichomonad be reconfirmed by appropriate laboratory measures. Total and differential leukocyte counts should be made before and after re-treatment.

Overdose

Single oral doses of Anazol, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Anazol has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Anazol overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.

Storage

Store below 77 degrees F (25 degrees C) and protect from light.

Side effects

The most common side effects associated with Anazol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Interaction with Alcohol. Use of oral metronidazole is associated with a disulfiram-like reaction to alcohol, including abdominal cramps, nausea, vomiting, headaches, and flushing. Discontinue consumption of alcohol or products containing propylene glycol during and for at least three days after therapy with metronidazole.

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Characteristics of time-domain optical coherence tomography profiles generated from blood-saline mixtures. Initiation of epileptiform activity in a rat model of periventricular nodular heterotopia. The published articles related to schistosomiasis in CNKI from 2005 to 2012 were collected, the citation frequency of the papers was calculated according to formula, and the highly cited papers were selected according to the citation frequency. A diagnosis of adenosquamous carcinoma was excluded by extensive histologic investigation of a large number of tissue samples--a total 122 sections from 25 blocks--that revealed neither glandular structures nor mucin. This variation may depend on the active photochemical reaction with OH radical during a period of intense solar radiation and changes in soil conditions together with variations in emissions. The general approach to prescribing medication is presented according to the status of the disease. Stable interaction of p105 with c-rel or p65 requires the putative dimerization domain in the conserved rel homology region of p105, as well as a second contact with the I kappa B-related C-terminal part of p105.

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Metabolic mechanisms involved in the impaired insulin secretion in pancreatic islets isolated from exercised and fasted rats. The occurrence of diabetic cardiomyopathy is independent of hypertension, coronary artery disease, or any other known cardiac diseases. In addition, variation in ovariole number among workers relates to worker sensory tuning, foraging behavior, and the ability to lay unfertilized male-destined eggs. For a small Debye length, a two-scale analysis for the quasineutral plasma and for the sheath provides analytical expressions for the emitted and collected currents and for the potential as functions of a generalized mass ratio. Tone discrimination and speech perception benefit in Mandarin-speaking children fit with HiRes fidelity 120 sound processing. These studies establish an early interplay between cardiomyocyte XO activation and bioenergetic dysfunction that may provide a new target that prevents progression to heart failure in VO. No significant variation in inflammatory markers with sleep duration was observed in men. Polyamines are suggested to play a role in the cellular immune response. The limited, but how to prevent yeast infection when taking flagyl very helpful radiologic findings in some cases are mentioned. The transport of bulk lipoproteins, micronutrients and morphogens to oocytes, in parallel with the maintenance of somatic homeostasis, is achieved by the cell-specific expression of receptors and subtle differences in the ligand structure that determine their target sites.

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