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Asmetic (Roxithromycin)

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Asmetic is indicated for the treatment of the following types of mild to moderately severe infections in adults caused by or likely to be caused by susceptible microorganisms. Upper respiratory tract infections: acute pharyngitis, tonsillitis, sinusitis.

Other names for this medication:
Asmetic, Assoral, Bazuctril, Bicofen, Biostatik, Cadithro, Claramid, Dorolid, Elrox, Floxid, Infectoroxit, Klomicina, Macrolid, Monobac, Odonticina, Overal, Pedilid, Redotrin, Ritosin, Rokilide, Roksimin, Roksolit, Rolexit, Romac, Romyk, Rossitrol, Rotramin, Roxacine, Roxithromycin, Roxithromycine, Roxithromycinum, Rulid

Similar Products:
Flagyl, Floxin, Biaxin, Chloromycetin, Sumycin, Zithromax, Terramycin, Amoxil

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Also known as: Roxithromycin


Asmetic is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Asmetic is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring. It is also currently undergoing clinical trials for the treatment of male-pattern hair loss.

Asmetic is available under several brandnames. Asmetic is not available in the United States. Asmetic is available in Australia, Israel and New Zealand. Asmetic has also been tested to possess antimalarial activity.

Asmetic prevents bacteria from growing, by interfering with their protein synthesis. Asmetic binds to the subunit 50S of the bacterial ribosome, and thus inhibits the synthesis of peptides. Asmetic has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly Legionella pneumophila.


Take Generic Asmetic by mouth with food. If you have trouble swallowing the tablet whole, it may be crushed or chewed with a little water. Swallow Generic Asmetic tablets whole with a glass of water. Generic Asmetic should be taken at least 15 minutes before food or on an empty stomach (i.e. more than 3 hours after a meal). Generic Asmetic works best if you take it on an empty stomach. For treating bacterial infections, Generic Asmetic is usually taken for 5 to 10 days. If you want to achieve most effective results do not stop taking Generic Asmetic suddenly.


Symptomatic treatment should be provided as required. There is no specific antidote.


Keep your tablets in the blister pack until it is time to take them. If you take the tablets out of the blister pack they may not keep well.

Keep the medicine in a cool, dry place where the temperature stays below 25 degrees C.

Do not store it or any other medicine in the bathroom, near a sink or on windowsill.

Do not leave it in the car. Heat and damp can destroy some medicines.

Keep it where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

Side effects

The most common side effects associated with Asmetic are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


The safety of roxithromycin has not been demonstrated in patients with impaired hepatic or renal function. Caution should be exercised if roxithromycin is administered to patients with impaired hepatic or renal function. If administered to patients with severe impaired hepatic function (eg. hepatic cirrhosis with jaundice and/or ascites), consideration should be given to reducing the daily dosage to half the usual dosage.

Prolonged or repeated use of antibiotics including roxithromycin may result in superinfection by resistant organisms. In the event of superinfection, roxithromycin should be discontinued and appropriate therapy instituted.

When indicated, incision, drainage or other appropriate surgical procedures should be performed in conjunction with antibiotic therapy.

Antibiotic associated pseudomembranous colitis has been reported with many antibiotics. A toxin produced by Clostridium difficile appears to be the primary cause. The severity of the colitis may range from mild to life threatening. It is important to consider this diagnosis in patients who develop diarrhoea or colitis in association with antibiotic use (this may occur up to several weeks after cessation of antibiotic therapy). Mild cases usually respond to drug discontinuation alone. However, in moderate to severe cases, appropriate therapy with a suitable oral antibacterial agent effective against Clostridium difficile should be considered. Fluids, electrolytes and protein replacement therapy should be provided when indicated.

Roxithromycin, like erythromycin, has been shown in vitro to elicit a concentration - dependent lengthening in cardiac action potential duration. Such an effect is manifested only at supra – therapeutic concentrations. Accordingly, the recommended doses should not be exceeded. In certain conditions macrolides, including roxithromycin, have the potential to prolong the QT interval. Therefore roxithromycin should be used with caution in patients with congenital prolongation of the QT interval, with ongoing proarrhythmic conditions (ie uncorrected hypokalemia or hypomagnesaemia, clinically significant bradycardia), and in patients receiving Class IA and III antiarrhythmic agents.

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Lead and cadmium in eggs of colonially nesting waterbirds of different position in the food chain of Greek wetlands of international importance. Pyruvate kinase specific activity increases upon the interaction with the phospholipids. Subsequently, a TaqMan real-time PCR approach was settled, using 6-carboxy-fluorescein group (FAM) and VIC-labelled specific probes for automated detection. The applied voltage, mobile phase, and gradient elution were optimized and applied for the analysis of urinary metabolites. Work is in progress on various bioengineering techniques to culture and combine bladder cells in tissue culture for regeneration. That the mental health problems are as common in the developing countries as in the developed ones has been amply shown by many epidemiological studies. A comparison was made of the ability to identify any abnormality on CT and a clinically important brain injury on CT, compared with a gold standard of a neuroradiology report.

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Using the same organocatalyst for asymmetric synthesis of both enantiomers of glutamic acid-derived Ni(II) complexes via 1,4-additions of achiral glycine and dehydroalanine Schiff base Ni(II) complexes. Adult rats are deficient in reversing a position choice and demonstrate impaired performance in a Y-maze. Sphingosine-1-phosphate receptor activation with fingolimod during acute MI reduced infarct size via the reperfusion injury salvage kinase and survivor activating factor enhancement pathways, improved systolic LV function, and mitigated post-MI LV remodeling. BiERapp provides an interactive and user-friendly interface that implements the filtering strategy used in the context of a large-scale genomic project carried out by the Spanish Network for Research in Rare Diseases (CIBERER) in which more than 800 exomes have been analyzed. We encountered a patient with spontaneous coronary artery dissection complicated by acute inferior myocardial infarction. NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux. In our patients, the complication rate increased after the use of an investigational urethral warmer was discontinued.

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Cushion formation is restricted to the AV canal and ventricular outflow tract regions of the primary heart tube. One hundred and forty-one patients with unresectable mCRC were enrolled in a randomized study comparing standard XELOX (XELOX(30)), arm A, and XELOX(30Chron), arm B-both with short-time infusion of oxaliplatin-with the primary aim of reducing overall toxicity. The addition of the N-terminal arm of Drosophila Antennapedia to the truncated form restores the DNA-binding affinity of dimers to values similar to those of the native form. Third, a positively skewed response was analyzed using a number of different generalized linear mixed models. Salts exert a different destabilizing effect on different sites of the macromolecule, promoting the detection of a thermostable domain.

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