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Azimakrol (Azithromycin)

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Azimakrol is an antibiotic useful for the treatment of a number of bacterial infections. This includes middle ear infections, strep throat, pneumonia, traveler's diarrhea, and certain other intestinal infections. It may also be used for a number of sexually transmitted infections including chlamydia and gonorrhea infections. Along with other medications, it may also be used for malaria.

Other names for this medication:
Amsati, Azadose, Azenil, Azicine, Azidraw, Azigram, Azihexal, Azimex, Azinil, Azinix, Azirox, Azithromax, Azithrus, Azitrin, Azitrix, Azitrocin, Azitropharma, Aziwok, Azomac, Azyter, Bactrazol, Ilozin, Momicine, Novatrex, Rozith, Sumamed, Texis, Toraseptol, Triamid, Trozocina, Zedd, Zetamax, Zibramax, Zistic, Zithrin, Zithrox, Zitrim, Zitroken, Zival, Zymycin

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Also known as: Azithromycin


Azimakrol (Azimakrol tablets and Azimakrol for oral suspension) contain the active ingredient azithromycin, a macrolide antibacterial drug, for oral administration. Azimakrol has the chemical name (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl) oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. Azimakrol is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring. Its molecular formula is C38H72N2O12, and its molecular weight is 749.00.

Azimakrol, as the dihydrate, is a white crystalline powder with a molecular formula of C38H72N2O12∙2H2O and a molecular weight of 785.0.

Azimakrol is supplied as tablets containing azithromycin dihydrate equivalent to either 250 mg or 500 mg azithromycin and the following inactive ingredients: dibasic calcium phosphate anhydrous, pregelatinized starch, sodium croscarmellose, magnesium stearate, sodium lauryl sulfate, hypromellose, lactose, titanium dioxide, triacetin, and D&C Red #30 aluminum lake.

Azimakrol for oral suspension is supplied in bottles containing azithromycin dihydrate powder equivalent to 300 mg, 600 mg, 900 mg, or 1200 mg azithromycin per bottle and the following inactive ingredients: sucrose; sodium phosphate, tribasic, anhydrous; hydroxypropyl cellulose; xanthan gum; FD&C Red #40; and spray dried artificial cherry, creme de vanilla, and banana flavors. After constitution, each 5 mL of suspension contains 100 mg or 200 mg of azithromycin.


It is important that your child completes the course of antibiotic. This means that they must take the medicine for the number of days that the doctor has told you to, or until all the medicine has been taken. If you stop giving the antibiotic too soon, the troublesome bacteria that are left will start to multiply again, and may cause another infection. There is also a risk that these bacteria will be resistant to (no longer be killed by) the first antibiotic. This means that it might not work next time, and your child might need a different antibiotic, which might not work as well or cause more side-effects.

Children are sometimes sick (vomit) or get diarrhoea when taking antibiotics. Encourage them to drink water to replace the fluid they have lost. If it is severe or your child is drowsy, contact your doctor.

Do not give your child any medicine to stop the diarrhoea unless your doctor has told you to, as this can make things worse.

Try to give the medicine at about the same times each day, to help you remember, and to make sure that there is the right amount of medicine in your child’s body to kill the bacteria.

Only give this medicine to your child for their current infection.

Never save medicine for future illnesses. Give old or unused antibiotics to your pharmacist to dispose of.

Only give the antibiotic to the child for whom it was prescribed. Never give it to anyone else, even if their condition appears to be the same, as this could do harm.


If you overdose Azimakrol and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Azimakrol overdosage: discomfort feeling in stomach, diarrhea, retching, nausea.


Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets. Do not store the liquid longer than 10 days.

Side effects

The most common side effects associated with Azimakrol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Ketolide allergy. History of cholestatic jaundice/hepatic dysfunction associated with prior use.

Pneumonia: oral treatment is for mild, community-acquired cases suitable for outpatient therapy only. Discontinue if signs/symptoms of hepatitis occur. Known QT prolongation, proarrhythmic conditions, clinically significant bradycardia: avoid. Allergic symptoms may recur after initial successful symptomatic treatment. Myasthenia gravis. Hepatic or renal impairment. Elderly. Pregnancy (Cat.B). Nursing mothers.

Avoid concomitant aluminum- or magnesium-containing antacids. Monitor with digoxin, phenytoin, warfarin. Monitor for azithromycin toxicity (eg, liver dysfunction, ototoxicity) with nelfinavir. Concomitant Class 1A (eg, quinidine, procainamide), or Class III (eg, dofetilide, amiodarone, sotalol) antiarrhythmics, or others known to prolong the QT interval: avoid.

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Rhythmic and non-rhythmic attractors in asynchronous random Boolean networks. Empiric antifungal therapy in febrile granulocytopenic patients. M13 DNA fingerprinting, a new tool for classification and identification of Lactobacillus spp. We observed a 3 month old infant who presented with marked atypical lymphocytosis and liver dysfunction. These data indicate that the Vpr-induced decrease of UNG2 level is mainly related to a transcriptional effect. The study indicates that pharmacists have a role in improving medication adherence, but its long-term effect on persistence warrants further studies with longer duration. Cooling to 29 and 20 degrees C diminished the relaxation, probably due to an attenuated release of EDRF. We reviewed 256 consecutive radical retropubic prostatectomies performed by 14 urologists during 4 years at a community hospital. We organised the findings into themes of what faulty staff teach to learners (habits of mind, such as higher-order thinking and metacognition), how they teach (guiding principles of clinical relevance and perspective shifting, and concrete strategies such as questioning and group interaction) and why they teach CT (to produce the best possible health outcomes for patients).

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Presynaptic nerve terminals pass through distinct stages of maturation after their initial assembly. The QFG-IT correctly detected TB in two baboons, including one TST negative individual and correctly identified six baboons as uninfected, including one TST positive individual. Comparison of proximal femoral nail and dynamic hip screw for treating intertrochanteric fractures. Intellectual property protections for biologic medicinals for multiple sclerosis (MS) are beginning to expire, opening the possibility of development, regulatory approval, and marketing of so-called follow-on biologics, biosimilars, or subsequent entry biologics that might be offered at lower price to consumers and third-party payers, as has been the case for generic drugs. This powerful strategy provides a practical and efficient approach to construct thioethers, using readily available aromatic amines and alkyl halides as starting materials. After controlling for these differences, the diabetics in all antidiabetic treatment groups still had a higher number of visits than non-diabetics.

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