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Azimed (Azithromycin)
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Azimed

Azimed is in a group of drugs called macrolide antibiotics. Azimed fights bacteria in the body. Azimed is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections, ear infections, and sexually transmitted diseases. Azimed may also be used for purposes other than those listed in this medication guide.

Other names for this medication:
Arzomicin, Azicine, Azigram, Azihexal, Azinom, Azithromax, Azithrox, Azitrovid, Azomex, Azrolid, Bactrazol, Cinalid, Gramokil, Koptin, Macromax, Macrozit, Magnabiotic, Neofarmiz, Neozith, Oranex, Phagocin, Respazit, Tremac, Tridosil, Zibramax, Zicho, Zifin, Zithromac, Zithrox, Zitrolab

Similar Products:
Cleocin, Noroxin, Vantin, Zithromax, Ilosone

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Also known as: Azithromycin

Description

Azimed (Azimed tablets and Azimed for oral suspension) contain the active ingredient azithromycin, a macrolide antibacterial drug, for oral administration. Azimed has the chemical name (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl) oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. Azimed is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring. Its molecular formula is C38H72N2O12, and its molecular weight is 749.00.

Azimed, as the dihydrate, is a white crystalline powder with a molecular formula of C38H72N2O12∙2H2O and a molecular weight of 785.0.

Azimed is supplied as tablets containing azithromycin dihydrate equivalent to either 250 mg or 500 mg azithromycin and the following inactive ingredients: dibasic calcium phosphate anhydrous, pregelatinized starch, sodium croscarmellose, magnesium stearate, sodium lauryl sulfate, hypromellose, lactose, titanium dioxide, triacetin, and D&C Red #30 aluminum lake.

Azimed for oral suspension is supplied in bottles containing azithromycin dihydrate powder equivalent to 300 mg, 600 mg, 900 mg, or 1200 mg azithromycin per bottle and the following inactive ingredients: sucrose; sodium phosphate, tribasic, anhydrous; hydroxypropyl cellulose; xanthan gum; FD&C Red #40; and spray dried artificial cherry, creme de vanilla, and banana flavors. After constitution, each 5 mL of suspension contains 100 mg or 200 mg of azithromycin.

Dosage

Generic Azimed is available in: 250 mg (Low Dosage), 500 mg (Standard Dosage).

Generic Azimed can be taken in tablets, liquid form, injections. You should take it by mouth with water.

To avoid problems with stomach, take tablets and liquid form with meals. Liquid Generic Azimed form should be shook properly. Capsule is taken on empty stomach.

It is better to take Generic Azimed every day at the same time.

Generic Azimed treats different types of bacterial infections and can be used both by adults and by children. Thus, each age has different instructions.

For children it is better to take into account child weight. In treatment of otitis media, take Generic Azimed for 1-5 days.

For Adults: if you treat Pneumonia or Throat/Tonsil Infection the right dose is two tablets of 250 mg on the first day and then 250 mg once a day for 4 more days.

In prevention of MAC (mycobacterium avium complex) usual Generic Azimed dosage is 1,200 mg for a week.

In treatment of skin or infections usual Generic Azimed dosage is two tablets of 250 mg at the first day after you took one tablet of 250 mg for 4 days at the same time.

Overdose

If you take an overdose of Azimed you should visit your doctor or health care provider immediately. Symptoms of Azimed overdosage include discomfort in the stomach, diarrhea, retching and nausea.

Storage

Keep the medicine in a cupboard, away from heat and direct sunlight.

You may need to keep liquid medicine in the fridge – check the instructions on the bottle. Make sure that the medicine doesn’t freeze.

Make sure that children cannot see or reach the medicine.

Keep the medicine in the container it came in.

Side effects

The most common side effects associated with Azimed are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Ketolide allergy. History of cholestatic jaundice/hepatic dysfunction associated with prior use.

Pneumonia: oral treatment is for mild, community-acquired cases suitable for outpatient therapy only. Discontinue if signs/symptoms of hepatitis occur. Known QT prolongation, proarrhythmic conditions, clinically significant bradycardia: avoid. Allergic symptoms may recur after initial successful symptomatic treatment. Myasthenia gravis. Hepatic or renal impairment. Elderly. Pregnancy (Cat.B). Nursing mothers.

Avoid concomitant aluminum- or magnesium-containing antacids. Monitor with digoxin, phenytoin, warfarin. Monitor for azithromycin toxicity (eg, liver dysfunction, ototoxicity) with nelfinavir. Concomitant Class 1A (eg, quinidine, procainamide), or Class III (eg, dofetilide, amiodarone, sotalol) antiarrhythmics, or others known to prolong the QT interval: avoid.

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Here, we show that the synthetic estrogen diethylstilbestrol (DES) promotes coactivator release from ERR beta and inhibits its transcriptional activity. Experimental results on these datasets show the outperformed or comparable effectiveness of FSVM-CIP. These data reveal a dominant immunosuppressive function of B-cell-derived IL-10 in the Lyn-deficient model of autoimmunity, extending our current understanding of the role of IL-10 and IL-10-producing B cells in systemic lupus erythematosus. Inhibition with nicotinamide revealed that sirtuin deacetylase activity in Tetrahymena cells promotes chromatin condensation during meiotic prophase, differentiation of heterochromatin from euchromatin during development, and chromatin condensation/degradation during programmed nuclear death. Causes of delay and associated mortality in patients transferred with ST-segment-elevation myocardial infarction. Comparison with calculations using a Tersoff-Hamann approach, including s- and p-wave tip states, demonstrates the significant contribution of p-wave tip states. We conclude that silvopasture increases the presence of infection by gastrointestinal nematoda in wild horses, especially by strongyles.

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Size resolved metal distribution in the PM matter of the city of Turin (Italy). The amino terminus of nerve growth factor (NGF) is susceptible to proteolytic cleavage. One explanation for this finding could be the sequestration of antibody-producing cells in the lymphoid tissue. Anesthetic potentiation of cardiac alpha 1-adrenoceptor effects may contribute to the generation of halothane-epinephrine dysrhythmias by abnormally slowing conduction and facilitating reentry. Performances of 14 paranoid schizophrenics, 13 nonparanoid schizophrenics, and 15 matched controls were compared on a facial affect judgment task, and a matched control task comprising geometric figures largely devoid of emotional information. Logistic models reveal that maternal educational level is a statistically significant predictor of pregnancy wastage and infant mortality. Our data suggest that the LC is involved in the central integration of SIP and that the modulating effects of 5-HT2 receptors on SIP depend upon the integrity of LC function.

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