Also known as: Azithromycin
Azitrim (Azitrim tablets and Azitrim for oral suspension) contain the active ingredient azithromycin, a macrolide antibacterial drug, for oral administration. Azitrim has the chemical name (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl) oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. Azitrim is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring. Its molecular formula is C38H72N2O12, and its molecular weight is 749.00.
Azitrim, as the dihydrate, is a white crystalline powder with a molecular formula of C38H72N2O12∙2H2O and a molecular weight of 785.0.
Azitrim is supplied as tablets containing azithromycin dihydrate equivalent to either 250 mg or 500 mg azithromycin and the following inactive ingredients: dibasic calcium phosphate anhydrous, pregelatinized starch, sodium croscarmellose, magnesium stearate, sodium lauryl sulfate, hypromellose, lactose, titanium dioxide, triacetin, and D&C Red #30 aluminum lake.
Azitrim for oral suspension is supplied in bottles containing azithromycin dihydrate powder equivalent to 300 mg, 600 mg, 900 mg, or 1200 mg azithromycin per bottle and the following inactive ingredients: sucrose; sodium phosphate, tribasic, anhydrous; hydroxypropyl cellulose; xanthan gum; FD&C Red #40; and spray dried artificial cherry, creme de vanilla, and banana flavors. After constitution, each 5 mL of suspension contains 100 mg or 200 mg of azithromycin.
Use Azitrim as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Azitrim is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Azitrim at home, a health care provider will teach you how to use it. Be sure you understand how to use Azitrim. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
Do not use Azitrim if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
o clear up your infection completely, use Azitrim for the full course of treatment. Keep using it even if you feel better in a few days.
Ask your health care provider any questions you may have about how to use Azitrim.
Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of an Azitrim overdose may include nausea, vomiting, diarrhea, and stomach discomfort.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Do not refrigerate or freeze the extended-release oral liquid. After water has been added to the powder, use the dose within 12 hours and throw away any unused liquid after your dose.
You may store the oral liquid at room temperature or in the refrigerator. Do not freeze the bottle. Do not keep the oral liquid for more than 10 days. Throw away any unused liquid after all doses are completed.