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Bactrazol (Azithromycin)
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Bactrazol

Bactrazol is a macrolide antibiotic of azalides group. Bactrazol inhibits RNA-dependent protein synthesis of sensitive microorganisms. It active against gram-positive bacteria: Staphylococcus aureus, Streptococcus spp. (including Streptococcus pneumoniae, Streptococcus pyogenes group A); gram-negative bacteria: Haemophilus influenzae, Haemophilus parainfluenzae, Haemophilus ducreyi, Moraxella catarrhalis, Escherichia coli, Bordetella pertussis, Bordetella parapertussis, Borrelia burgdorferi, Neisseria gonorrhoeae, Campylobacter spp., Legionella pneumophila; anaerobic bacteria: Bacteroides fragilis.

Other names for this medication:
Arzomicin, Azibiot, Azicin, Azicine, Azigram, Azinom, Azithrex, Azithrocine, Binozyt, Disithrom, Ezith, Fabramicina, Goldamycin, Goxil, Hemomycin, Maczith, Medimacrol, Mezatrin, Neozith, Oranex, Penalox, Toraseptol, Vectocilina, Zetamax, Zibac, Zithrocin, Zithromac, Zithrox, Zitrolid

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Cipro, Chloromycetin, Avelox, Levaquin, Cleocin, Amoxil, Sumycin, Flagyl, Cefixime

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Also known as: Azithromycin

Description

Bactrazol is used to treat bacterial infections in many different parts of the body. It is also used to prevent Mycobacterium avium complex (MAC) disease in patients infected with the human immunodeficiency virus (HIV).

Bactrazol belongs to the class of drugs known as macrolide antibiotics. It works by killing bacteria or preventing their growth. However, Bactrazol will not work for colds, flu, or other virus infections. Bactrazol injection may be used for other problems as determined by your doctor.

Bactrazol is available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, Bactrazol is used in certain patients with the following medical condition: Trachoma (treatment).

Dosage

Dosage of Bactrazol is setted individually according to nosology, disease severity and sensitivity of the pathogen. Dosage for adults for oral administration is 0.25-1 g 1 time/day; for children - 5-10 mg/kg 1 time/day. The duration of administration is 2-5 days.

Overdose

Adverse reactions experienced at higher than recommended doses were similar to those seen at normal doses particularly nausea, diarrhea, and vomiting. In the event of overdosage, general symptomatic and supportive measures are indicated as required.

Storage

Store Bactrazol below 86 degrees F (30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Bactrazol out of the reach of children and away from pets.

Side effects

The most common side effects associated with Bactrazol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Ketolide allergy. History of cholestatic jaundice/hepatic dysfunction associated with prior use.

Pneumonia: oral treatment is for mild, community-acquired cases suitable for outpatient therapy only. Discontinue if signs/symptoms of hepatitis occur. Known QT prolongation, proarrhythmic conditions, clinically significant bradycardia: avoid. Allergic symptoms may recur after initial successful symptomatic treatment. Myasthenia gravis. Hepatic or renal impairment. Elderly. Pregnancy (Cat.B). Nursing mothers.

Avoid concomitant aluminum- or magnesium-containing antacids. Monitor with digoxin, phenytoin, warfarin. Monitor for azithromycin toxicity (eg, liver dysfunction, ototoxicity) with nelfinavir. Concomitant Class 1A (eg, quinidine, procainamide), or Class III (eg, dofetilide, amiodarone, sotalol) antiarrhythmics, or others known to prolong the QT interval: avoid.

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