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Biostatik (Roxithromycin)

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Biostatik is an antibiotic that is used to treat infections such as infections of the chest, tonsils, skin or genitals. It works by killing or stopping the growth of bacteria (bugs). Like all antibiotics, Biostatik is not effective against infections caused by viruses.

Other names for this medication:
Acevor, Aristomycin, Asmetic, Assoral, Azuril, Bazuctril, Biaxsig, Bicofen, Biostatik, Cadithro, Claramid, Crolix, Delos, Dorolid, Elrox, Erybros, Floxid, Infectoroxit, Klomicina, Ladlid, Macrolid, Macrosil, Makrodex, Monobac, Odonticina, Overal, Pedilid, Pedrox, Ramivan, Redotrin, Remora, Renicin, Ritosin, Rokilide, Rokithrid, Roksimin, Roksolit, Rolexit, Rolicyn, Rolid, Romac, Romyk, Rossitrol, Rotramin, Roxacine, Roxithromycin, Roxithromycine, Roxithromycinum, Roxitromicina, Rulid

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Suprax, Myambutol, Ceftin, Omnicef, Rulide, Terramycin, Sumycin

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Also known as: Roxithromycin


Biostatik is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Biostatik is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring. It is also currently undergoing clinical trials for the treatment of male-pattern hair loss.

Biostatik is available under several brandnames. Biostatik is not available in the United States. Biostatik is available in Australia, Israel and New Zealand. Biostatik has also been tested to possess antimalarial activity.

Biostatik prevents bacteria from growing, by interfering with their protein synthesis. Biostatik binds to the subunit 50S of the bacterial ribosome, and thus inhibits the synthesis of peptides. Biostatik has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly Legionella pneumophila.


Take Generic Biostatik by mouth with food. If you have trouble swallowing the tablet whole, it may be crushed or chewed with a little water. Swallow Generic Biostatik tablets whole with a glass of water. Generic Biostatik should be taken at least 15 minutes before food or on an empty stomach (i.e. more than 3 hours after a meal). Generic Biostatik works best if you take it on an empty stomach. For treating bacterial infections, Generic Biostatik is usually taken for 5 to 10 days. If you want to achieve most effective results do not stop taking Generic Biostatik suddenly.


Immediately telephone your doctor or pharmacist. Do this even if there are no signs of discomfort or poisoning.


Keep your tablets in the blister pack until it is time to take them. If you take the tablets out of the blister pack they may not keep well.

Keep the medicine in a cool, dry place where the temperature stays below 25 degrees C.

Do not store it or any other medicine in the bathroom, near a sink or on windowsill.

Do not leave it in the car. Heat and damp can destroy some medicines.

Keep it where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

Side effects

The most common side effects associated with Biostatik are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


The safety of roxithromycin has not been demonstrated in patients with impaired hepatic or renal function. Caution should be exercised if roxithromycin is administered to patients with impaired hepatic or renal function. If administered to patients with severe impaired hepatic function (eg. hepatic cirrhosis with jaundice and/or ascites), consideration should be given to reducing the daily dosage to half the usual dosage.

Prolonged or repeated use of antibiotics including roxithromycin may result in superinfection by resistant organisms. In the event of superinfection, roxithromycin should be discontinued and appropriate therapy instituted.

When indicated, incision, drainage or other appropriate surgical procedures should be performed in conjunction with antibiotic therapy.

Antibiotic associated pseudomembranous colitis has been reported with many antibiotics. A toxin produced by Clostridium difficile appears to be the primary cause. The severity of the colitis may range from mild to life threatening. It is important to consider this diagnosis in patients who develop diarrhoea or colitis in association with antibiotic use (this may occur up to several weeks after cessation of antibiotic therapy). Mild cases usually respond to drug discontinuation alone. However, in moderate to severe cases, appropriate therapy with a suitable oral antibacterial agent effective against Clostridium difficile should be considered. Fluids, electrolytes and protein replacement therapy should be provided when indicated.

Roxithromycin, like erythromycin, has been shown in vitro to elicit a concentration - dependent lengthening in cardiac action potential duration. Such an effect is manifested only at supra – therapeutic concentrations. Accordingly, the recommended doses should not be exceeded. In certain conditions macrolides, including roxithromycin, have the potential to prolong the QT interval. Therefore roxithromycin should be used with caution in patients with congenital prolongation of the QT interval, with ongoing proarrhythmic conditions (ie uncorrected hypokalemia or hypomagnesaemia, clinically significant bradycardia), and in patients receiving Class IA and III antiarrhythmic agents.

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The oncogenic phosphatase PPM1D confers cisplatin resistance in ovarian carcinoma cells by attenuating checkpoint kinase 1 and p53 activation. This study aimed to implement and evaluate a CVD prevention program in a rural area of India. The in vivo anti-tumor effect of SGLXD was evaluated in non-ovariectomized and ovariectomized athymic nude mice. Diagnoses do not provide a satisfactory description of the stay in the intensive care unit. To study the effect of colchicine on hepatic glycosaminoglycan (GAG) metabolism in mice infected with Schistosoma japonicum. HLA-G(pos) T(reg) were analyzed in the cerebrospinal fluid (CSF) by flow cytometry and in inflammatory demyelinating lesions of MS brain specimens by immunohistochemistry.

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Since MMP-3 and VEGF serum levels were found significantly higher in patients with malignant adrenal incidentalomas than in those with benign ones, they might be applied as markers of malignancy of incidentalomas. It is shown that determination of some metals in the cerebrospinal fluid allows to diagnose edema swelling of the brain and to predict the disease sequels. The aim of the present study was to determine whether insulin demand is increased in children with islet autoantibodies. We have recently shown that nucleotide excision repair (NER) and RecBCD-dependent homologous recombination (HR) collaboratively alleviate the lethal effect of DPCs in Escherichia coli. Munchausen syndrome by proxy: a profile for medical child abuse. Digital impressions obtained by the intraoral video scanner showed better accuracy for long-span areas than those captured by the still image scanner. None of these mutants substantially affected the response of the channel to extracellular acidification. Staff behavior, the design of the environment, the lack of accessible occupations, and the degree to which patients can decide whether to receive or decline visits affect the possibility to make their wishes a reality. The study presents experimental finding of 40 mongrel dogs whose intravascular blood was irradiated with laser as a supplement to the multimodality treatment of respiratory tuberculosis.

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Cytologic specimens are routinely collected as part of gynecologic oncology surgery. The study design and characteristics of the Danish national health interview surveys. It is shown that in particular, newly recruited macrophages play a crucial role in the generation of clinical signs. A patient with chronic inflammatory demyelinating polyradiculoneuropathy and systemic lupus erythematosus arising after rubella vaccination was initially treated with plasmapheresis, corticosteroids and intravenous immunoglobulins, with partial response. Because postoperative fluid collections are relatively common, the radiologist must be vigilant for any nodular-enhancing foci that are actually residual or recurrent tumor. Spatial diffusion of water in carbon nanotubes: from fickian to ballistic motion. The results also indicate that the rate at which the equilibrium condition is approached depends significantly on the functional form of the spatial distribution of the density of the immobilized ligands. Optic nerves in Sprague-Dawley rats were crushed intraorbitally at 2 mm behind eyeball by using a forceps with a 140-gram chucking power for 30 s to induce unilateral injured model. Besides that 3 of them are dark-inducible, their functions do not point to any known responses of plants to environmental stimuli.

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The evaluation turned out to be very effective in optimizing the parameters for signal processing. At least three ACADs were already present at that time: ancestral glutaryl-CoA dehydrogenase (GCD), isovaleryl-CoA dehydrogenase (IVD), and ACAD10/11. Suicide attempts are quite common among adolescents and suicide quite rare, yet the risk of later death among attempters is substantial. A number of recent studies have shown that the severity of endothelial dysfunction correlates with the development of coronary artery disease and predicts future cardiovascular events. gamma-Glutamyltransferase (GGT), an enzyme responsible for the extracellular catabolism of antioxidant glutathione, may explicitly participate in atherogenesis. Monostotic fibrous dysplasia of the proximal femur: natural history and predisposing factors for disease progression. Because cognitive measures fail to account for the majority of performance differences, noncognitive attributes must contribute to the poorer performance of URMs. Early-onset osteoarthritis, Charcot-Marie-Tooth like neuropathy, autoimmune features, multiple arterial aneurysms and dissections: an unrecognized and life threatening condition. In contrast, new positions open in 1999 or anticipated flagyl alcohol use to be open in the subsequent 3 years were 604.

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Ten out of sixteen blastomere-derived morulae attached to the MEFs, and two produced an outgrowth. Even the presence of wildtype p53 for up to four weeks post-IR provided no protection against early lymphoma incidence, indicating that long term maintenance of functional p53 is critical for preventing the emergence of a cancer. Handing over of a structure and requirement analysis to the public. Technical refinements in the new instruments and extensive acceptance of the advantages of the method makes fiberendoscopy a procedure widely used throughout the world. Many immunologically mediated glomerular diseases can be successfully treated, but clinicians should be wary of unproven claims of efficacy, be cognizant of long-term deleterious effects of treatment, and should select patients with a careful eye on the natural history of the untreated disorder. In all groups, the CIT levels were higher in brain tissue as compared to serum. Our analysis reveals that genes in complexes show more severe fitness effects upon deletion than other genes but, in contrast to what has been observed in binary protein-protein interaction networks, we find that this is not related to the number of complexes in which they are present. The treatment of choice is irradiation to both testicles and combination chemotherapy.

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CT images of 32 women with clinically proven acute PID and 32 control subjects with other conditions of similar presentation were retrospectively reviewed. The role of psychosocial and biological variables in separating chronic and non-chronic major depression and early-late-onset dysthymia. We included in this study ten BD patients who fulfilled the criteria for diagnosis, according to the International Study Group for BD. Here we will review these post-translational proteolytic regulations with a special emphasis on plant research and also discuss their functional relevance. Therefore, this systematic review focuses on the question of whether screening for amblyopia in children up to the age of six years leads to better vision outcomes. Production and characterization of domain-specific monoclonal antibodies against human ECM1. The two methods correlate quite well with the conventional classification (in Germany). Recent studies have highlighted the importance of renal parenchymal quality and quantity postoperatively rather than duration of ischemia in determining long-term renal function.

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The transition from maternal to zygotic gene expression in the mouse occurs in the 2-cell embryo. Histological studies of the mesenteric artery and the endometrium following haemostatis revealed that the haemostatic plug in the mesenteric artery was mainly composed of platelets and fibrin whereas in the endometrium it was mainly composed of fibrin. The author presents his experience where reflation of the dural tube provided immediate control of epidural bleeding. S6K phosphorylation is a possibly useful pharmacodynamic marker in HER2-targeted therapy. Smad7 markedly decreased the activity of the survival NF-kappaB transcription factor in MDCK cells. Here, we investigated matrix remodeling and zithromax dosage instructions wound healing in mice harboring gain of function or loss of function mutations of Egr-1. On the basis of previous studies that investigated the value of ictal semiology in localization and lateralization, we compared the experiential localization and/or lateralization of the epileptogenic region deduced from ictal semiology, that is, both seizure history and ictal video/EEG monitoring, with MEG localization.

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Comparison of two methods for the small-scale extraction of DNA from subgingival microorganisms. Alterations in appendicular skeletal mass in patients with rheumatoid arthritis, psoriatic arthritis, and osteoarthritis. We compared the efficacy of ADV and ETV rescue monotherapy in HBeAg-positive patients with confirmed genotypic 3TC resistance. Hazards of antioxidant combinations containing superoxide dismutase. Predictors of patient referrals by primary care residents to specialty care clinics. No author has a financial or proprietary interest in any material or method mentioned.

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