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Cefodox (Cefpodoxime)
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Cefodox

Cefodox (generic name: cefpodoxime proxetil; brand names include: Cefocep) is used for treating mild to moderate infections caused by certain bacteria. Cefodox is an oral third generation cephalosporin antibiotic. It is used to treat infections such as pneumonia; bronchitis; gonorrhea; and ear, skin, throat, and urinary tract infections. Cefodox works by interfering with the formation of the bacteria's cell wall so that the wall ruptures, resulting in the death of the bacteria. It treats many kinds of infections, including those of the respiratory tract, skin, and ears.

Other names for this medication:
Belpro, Cefdolife, Cefdox, Cefirax, Cefobid, Cefodox, Cefolex, Cefomin, Cefoprox, Cefpodoxim, Cefpodoxima, Cefpodoxime, Cefpodoximum, Cefpolek, Ceftils, Cepdoxim, Cepodem, Cepodix, Desbac, Dofixim, Edrigard, Instana, Kindcef, Orelox, Otreon, Pedicef, Pocef, Podomexef, Podoxi, Rovantin, Sefox, Starin, Starpod, Tambac, Taxetil, Trucef, Victorin, Weijiexin, Ximeprox, Ximocef

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Also known as: Cefpodoxime

Description

Cefodox is an oral, third-generation cephalosporin antibiotic. It is active against most Gram-positive and Gram-negative organisms. Notable exceptions include Pseudomonas aeruginosa, Enterococcus, and Bacteroides fragilis. Currently, it is only marketed as generic preparations in the USA, according to the FDA Orange Book. It is commonly used to treat acute otitis media, pharyngitis, sinusitis, and gonorrhea. It also finds use as oral continuation therapy when intravenous cephalosporins (such as ceftriaxone) are no longer necessary for continued treatment.

Cefodox inhibits cell wall synthesis by inhibiting the final transpeptidation step of peptidoglycan synthesis in cell walls. It has well established pharmacokinetic profile with absorption of 50%. It is indicated in community acquired pneumonia, uncomplicated skin and skin structure infections, and uncomplicated urinary tract infections.

Dosage

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Take this medicine with a full glass of water.

The Cefodox tablet should be taken with food.

Cefodox oral suspension (liquid) can be taken with or without food.

Shake the liquid well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

This medication can cause you to have false results with certain medical tests, including urine glucose (sugar) tests. Tell any doctor who treats you that you are using Cefodox.

Take Cefodox for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Cefodox will not treat a viral infection such as the common cold or flu.

Store the tablets at room temperature away from moisture, heat, and light.

Store Cefodox oral liquid in the refrigerator. Do not allow it to freeze. Throw away any unused medication that is older than 14 days.

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include nausea, vomiting, stomach pain, and diarrhea.

Take the medication as soon as you remember the missed dose. If it is almost time for your next dose, skip the missed dose and use the medicine at your next regularly scheduled time. Do not use extra medicine to make up the missed dose.

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include nausea, vomiting, stomach pain, and diarrhea.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. After mixing the suspension store in a refrigerator between 2 and 8 degrees C (36 and 46 degrees F). Do not freeze. Throw away unused portion after fourteen days. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Cefodox are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take this medication if you are allergic to cefpodoxime, or to similar antibiotics, such as Ceftin, Cefzil, Keflex, Omnicef, and others.

Before taking this medication, tell your doctor if you are allergic to any drugs (especially penicillin). Also tell your doctor if you have kidney disease or a history of intestinal problems.

Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Cefpodoxime will not treat a viral infection such as the common cold or flu.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

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The aim of this study was to determine the nature of PFM involvement in women with PVD via an evaluation of the biometry of the levator hiatus at rest, upon maximal voluntary contraction (MVC) of the PFMs, and upon maximal Valsalva maneuver (MVM). Pyoderma gangrenosum as a complication of coronary artery bypass grafting. The patients in the two families shared a common disease haplotype. Meta-Analysis of the Efficiency and Prognosis of Intracranial Aneurysm Treated with Flow Diverter Devices. The design of the robotic head, Muecas, is based on ongoing research on the mechanisms of perception and imitation of human expressions and emotions. High-resolution magnetic resonance imaging (HR-MRI) findings helped diagnose the existence of a mass at the subungual area and all patients were treated with excision and biopsy. Fine needle aspiration (FNA) biopsy showed cellular smears composed of sheets and aggregates of cuboidal to low columnar cells with slightly irregular nuclear contours, prominent nucleoli and a moderate amount of cytoplasm that appeared squamoid and finely vacuolated.

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Dynamic coupling of complex brain networks and dual-task behavior. In certain circumstances the hyperbola reduces to a straight line, simplifying the construction of the cone. Asymptomatic biliary lithiasis can be defined as biliary lithiasis having determined no complication and no episode of biliary pain. Resource utilization and costs for treatment of stroke patients in an acute stroke unit in Greece. The IRIS Medical G-Probe used in conjunction with a semiconductor diode laser may be the superior alternative to previously available cyclodestructive techniques for which ophthalmologists have been searching. Polycythaemia rubra vera presenting with depression: recognising the syndrome abulia. In chronic leukemia GSH and GST were increased, whereas Atase, GPx and frequency of Pgp-expression were low. Signals are also detected in selective regions of the adult brain, and in embryonic skeletal muscle.

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Role of endothelium in the human uterine arteries during normal menstrual cycle. Cattle in a slaughterhouse were visually inspected and assigned to a category from 1 (very clean) to 5 (very dirty) based on cleanliness. The past decades have seen an explosive growth in the application of density functional theory (DFT) methods to molecular systems that are of interest in a variety of scientific fields. Adaptability and selectivity of human peroxisome proliferator-activated receptor (PPAR) pan agonists revealed from crystal structures. The serum carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9) levels were assayed, and radiological examinations were performed routinely for 5 years after surgery or until recurrence was detected. The aim of the study was to evaluate the level of agreement between bitewing radiographs and oblique lateral radiographs for the diagnosis of dental caries extending into dentine, and to draw conclusions from the results as to which view is more useful. Further clinical trials are necessary to clarify the value of new pacing techniques.

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Prospective evaluation in patients with solitary kidneys may better elucidate its potential renoprotective role in this setting. A study was designed to determine the diabetes related knowledge levels of practice nurses in a regional/rural setting in Australia. This exploratory study examined the characteristics and experiences of seventy-three older unemployed workers, age fifty and above, who were discouraged and had stopped searching for a full-time job. To this end, it presents the general background against which the joint paper should be understood. Neglecting nuclear quantum effects prevents an accurate description of the structure, the properties of water below 120 K and the heat capacity. Activation of SHIP via a small molecule agonist kills multiple myeloma cells. FnECHO is frequently used in the NICU setting and may be a useful tool to guide treatment. Within the group of denervation atrophies, NMAs due to motor neuron diseases are associated with particular histological patterns. The presence of 7,7-dimethylaporphine alkaloids in this species is important for the chemotaxonomy of Guatteriopsis. Infected non union in this area provides a challenge to the orthopaedic surgeon.

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The interpretation of the changes of cerebral oxygen saturation with respect to neurological outcome warrants further studies. It was previously shown that the B subunit had no effect on cAMP, protein kinase C or phosphoinositide turnover, but did cause an increase in the influx of calcium from extracellular sources (Spiegel, S. Sternal skin, shoulders and upper arms, earlobes, and cheeks are most susceptible to developing keloids and hypertrophic scars. We assessed COX-2 expression and promoter methylation status in six gastric epithelial cell lines. Fourty-six patients suspected of having postoperative abscess were examined. Use of bacterially expressed EBNA-1 protein cloned from a nasopharyngeal carcinoma (NPC) biopsy as a screening test for NPC patients.

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Secretion of histamine, serotonin, insulin, and hydrocortisone was increased in spring and reduced in autumn. To study phagocytosis of apoptotic cells (AC) by macrophages in tissue, we validated different apoptosis markers (DNA fragmentation, caspase-3 activation and cleavage of its substrate poly(ADP-ribose)polymerase-1) in combination with macrophage immunostaining. With a level playing field, this screening platform can identify the best bimetallic combination for a catalytic reaction, before optimizing the synthesis. In these cases, significant sequence identity could be detected throughout the entire region even though the repeat array was not detected in one of the sequences. Its molecular weight, amino acid composition and substrate specificity were shown to display minor differences from materials of other origins. The factors contributing to or reducing the achievement of the final objective of malaria elimination--to interrupt the local transmission of the infection and to steadily maintain the achieved successes are given. The selective procedure was applied to the analysis of the amino acid side chains that are important for the attainment of the correct conformation of the carboxy-terminal E helix in the 4-fold axis.

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