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Cefpolek (Cefpodoxime)

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Cefpolek is used to treat a wide variety of bacterial infections. Cefpolek is known as a cephalosporin antibiotic. It works by stopping the growth of bacteria. This antibiotic treats only bacterial infections.

Other names for this medication:
Cefdox, Cefirax, Cefobid, Cefodox, Cefpodoxim, Cefpodoxima, Cefpodoximum, Cefpolek, Ceftils, Cepdoxim, Cepodem, Cepodix, Desbac, Dofixim, Edrigard, Instana, Kindcef, Orelox, Otreon, Pocef, Podomexef, Podoxi, Rovantin, Sefox, Starin, Starpod, Tambac, Taxetil, Trucef, Weijiexin, Ximocef

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Chloromycetin, Zithromax, Levaquin, Noroxin, Floxin

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Also known as: Cefpodoxime


Cefpolek is an oral, third-generation cephalosporin antibiotic. It is active against most Gram-positive and Gram-negative organisms. Notable exceptions include Pseudomonas aeruginosa, Enterococcus, and Bacteroides fragilis. Currently, it is only marketed as generic preparations in the USA, according to the FDA Orange Book. It is commonly used to treat acute otitis media, pharyngitis, sinusitis, and gonorrhea. It also finds use as oral continuation therapy when intravenous cephalosporins (such as ceftriaxone) are no longer necessary for continued treatment.

Cefpolek inhibits cell wall synthesis by inhibiting the final transpeptidation step of peptidoglycan synthesis in cell walls. It has well established pharmacokinetic profile with absorption of 50%. It is indicated in community acquired pneumonia, uncomplicated skin and skin structure infections, and uncomplicated urinary tract infections.


Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Take this medicine with a full glass of water.

The Cefpolek tablet should be taken with food.

Cefpolek oral suspension (liquid) can be taken with or without food.

Shake the liquid well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

This medication can cause you to have false results with certain medical tests, including urine glucose (sugar) tests. Tell any doctor who treats you that you are using Cefpolek.

Take Cefpolek for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Cefpolek will not treat a viral infection such as the common cold or flu.

Store the tablets at room temperature away from moisture, heat, and light.

Store Cefpolek oral liquid in the refrigerator. Do not allow it to freeze. Throw away any unused medication that is older than 14 days.

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include nausea, vomiting, stomach pain, and diarrhea.

Take the medication as soon as you remember the missed dose. If it is almost time for your next dose, skip the missed dose and use the medicine at your next regularly scheduled time. Do not use extra medicine to make up the missed dose.


Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include nausea, vomiting, stomach pain, and diarrhea.


Store Cefpolek at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 to 86 degrees F (15 to 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Cefpolek out of the reach of children and away from pets.

Side effects

The most common side effects associated with Cefpolek are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take this medication if you are allergic to cefpodoxime, or to similar antibiotics, such as Ceftin, Cefzil, Keflex, Omnicef, and others.

Before taking this medication, tell your doctor if you are allergic to any drugs (especially penicillin). Also tell your doctor if you have kidney disease or a history of intestinal problems.

Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Cefpodoxime will not treat a viral infection such as the common cold or flu.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

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