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Chibroxine (Norfloxacin)
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Chibroxine

Chibroxine is a fluoroquinolone antibiotic. Chibroxine works by blocking DNA gyrase enzyme, which is responsible for production and repair of bacterial DNA. Blocking of DNA gyrase leads to bacteria death and prevents worsening of infection.

Other names for this medication:
Apirol, Bacteriotal, Basteen, Bexinor, Biscolet, Constilax, Epinor, Esclebin, Floxamed, Fluseminal, Foxgoria, Gyrablock, Janacin, Lexinor, Loxone, Microxin, Naflox, Nalion, Noflo, Nofloxan, Nofocin, Noprose, Norax, Noraxin, Norflogen, Norflohexal, Norfloxacin, Normax, Noroxine, Noxacin, Ovinol, Pistofil, Renoxacin, Shinun, Theanorf, Trizolin, Unasera, Uritracin, Uroquin, Uroseptal, Utibid, Utinor, Vefloxa, Wenflox, Xasmun, Zoroxin

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Also known as: Norfloxacin

Description

Generic Chibroxine medication belongs to a class of drugs called quinolone antibiotics. Generic Chibroxine works by stopping the growth of bacteria. Generic Chibroxine should not be used for colds, flu, other virus infections, sore throats or other minor infections, or to prevent infections. Chibroxine is also known as Norfloxacin, Norfloxacine, Apo-Norflox, Norflohexal, Roxin, Utinor. Generic name of Generic Chibroxine is Norfloxacin. Brand name of Generic Chibroxine is Chibroxine.

Dosage

Before taking Chibroxine tell your doctor and pharmacist if you are allergic or have had a severe reaction to Chibroxine; other quinolone or fluoroquinolone antibiotics such as ciprofloxacin (Cipro), gatifloxacin (Tequin) (not available in the U.S.), gemifloxacin (Factive), levofloxacin (Levaquin), lomefloxacin (Maxaquin) (not available in the U.S.), moxifloxacin (Avelox), nalidixic acid (NegGram), ofloxacin (Floxin), and sparfloxacin (Zagam) (not available in the U.S.), or any other medications.

Tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, herbal products, and nutritional supplements you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: other antibiotics; anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); certain antidepressants; antipsychotics (medications to treat mental illness); caffeine or medications that contain caffeine (Excedrin, NoDoz, Vivarin, others); cisapride (Propulsid) (not available in the U.S.); clozapine (Clozaril, Fazaclo); cyclosporine (Gengraf, Neoral, Sandimmune); diuretics ('water pills'); erythromycin (E.E.S, E-Mycin, Erythrocin, others); glyburide (DiaBeta, in Glucovance, Micronase, others); certain medications for irregular heartbeat such as amiodarone (Cordarone), procainamide (Procanbid), quinidine, and sotalol (Betapace, Betapace AF, Sorine); nitrofurantoin (Furadantin, Macrobid, Macrodantin); probenecid (in Col-Probenecid, Probalan); nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin, others) and naproxen (Aleve, Naprosyn, others); ropinirole (Requip); tacrine (Cognex); theophylline (Elixophyllin, Theo-24, Uniphyl, others); and tizanidine (Zanaflex). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

If you are taking antacids containing aluminum hydroxide or magnesium hydroxide (Maalox, Mylanta, Tums, others), didanosine (Videx) sucralfate (Carafate), or supplements or multivitamins that contain iron or zinc, take these medications 2 hours before or 2 hours after you take Chibroxine.

Tell your doctor if you or anyone in your family has or has ever had a prolonged QT interval (a rare heart problem that may cause irregular heartbeat, fainting or sudden death) or an irregular heartbeat and if you have or have ever had nerve problems, a low level of potassium in your blood, a slow heartbeat, chest pain, seizures, myasthenia gravis (condition that causes weakness of certain muscles), cerebral arteriosclerosis (narrowing of blood vessels in or near the brain that can lead to stroke or mini-stroke), or glucose-6-phosphate dehydrogenase (G-6PD) deficiency (an inherited blood disorder).

Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking Chibroxine, call your doctor.

You should know that this medication may cause dizziness, lightheadedness, and tiredness. Do not drive a car, operate machinery, or participate in activities requiring alertness and coordination until you know how Chibroxine affects you.

Plan to avoid unnecessary or prolonged exposure to sunlight or ultraviolet light (tanning beds and sunlamps) and to wear protective clothing, sunglasses, and sunscreen. Chibroxine may make your skin sensitive to sunlight or ultraviolet light. If your skin becomes reddened, swollen, or blistered, call your doctor.

Overdose

If you overdose Generic Chibroxine and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Chibroxine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You may be taking certain other medicines that should not be taken at the same time as norfloxacin. Avoid taking the following medicines within 2 hours before or after you take norfloxacin. These other medicines can make norfloxacin much less effective when taken at the same time: antacids that contain magnesium or aluminum (such as Maalox, Mylanta, or Rolaids); the ulcer medicine sucralfate (Carafate); didanosine (Videx) powder or chewable tablets; or vitamin or mineral supplements that contain iron or zinc.

Avoid caffeine while you are taking norfloxacin, because the medication can make the effects of caffeine stronger.

Avoid exposure to sunlight or tanning beds. Norfloxacin can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Call your doctor if you have severe burning, redness, itching, rash, or swelling after being in the sun.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking norfloxacin and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.

Norfloxacin may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

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