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Clacee (Clarithromycin)
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Clacee

Clacee is also effective against some infections (e.g., MAC or Mycobacterium avium complex) seen in people with reduced immunity. It stops the bacteria from growing, which helps to resolve your symptoms and cure your infection. This medicine is taken orally, preferably either one hour before or 2 hours after a meal.

Other names for this medication:
Aeroxina, Biotclarcin, Ciclinil, Cidoclar, Clacee, Clacina, Clamycin, Clarimac, Clarimed, Clarimycin, Claripen, Claritab, Claritt, Claromac, Clatic, Finasept, Gervaken, Helozym, Infex, Karid, Klabet, Klarimac, Klonacid, Krobicin, Macladin, Maclar, Mononaxy, Monozeclar, Rodizim, Rolicytin, Taclar, Zeclar

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Also known as: Clarithromycin

Description

Clacee (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac / Claribid) is used to treat many different types of bacterial infections affecting the skin and respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis (inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.

It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.

It also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Clacee works by stopping the growth of or killing sensitive bacteria by interfering with their protein synthesis.

Dosage

The recommended daily dosage is 15 mg/kg/day divided every 12 hours for 10 days (up to the adult dose). Refer to dosage regimens for mycobacterial infections in pediatric patients for additional dosage information.

For the treatment of disseminated infection due to Mycobacterium avium complex (MAC), Clacee Filmtab and Clacee Granules are recommended as the primary agents. Clacee Filmtab and Clacee Granules should be used in combination with other antimycobacterial drugs (e.g. ethambutol) that have shown in vitro activity against MAC or clinical benefit in MAC treatment.

For treatment and prophylaxis of mycobacterial infections in adults, the recommended dose of Clacee is 500 mg every 12 hours.

For treatment and prophylaxis of mycobacterial infections in pediatric patients, the recommended dose is 7.5 mg/kg every 12 hours up to 500 mg every 12 hours.

Clacee therapy should continue if clinical response is observed. Clacee can be discontinued when the patient is considered at low risk of disseminated infection.

Overdose

If you overdose Clacee and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Clacee overdosage: nausea, vomiting, diarrhea, abdominal discomfort.

Storage

Store Clacee XL Filmtab at 20 to 25 degrees C (68 to 77 degrees F). Excursions permitted to 15 to 30 degrees C (59 to 86 degrees F).

Side effects

The most common side effects associated with Clacee are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Concomitant cisapride, pimozide, ergots, HMG-CoA reductase inhibitors extensively metabolized by CYP3A4 (lovastatin or simvastatin). History of QT prolongation or ventricular cardiac arrhythmia (including torsades de pointes). Concomitant colchicine (in renal or hepatic impairment). Cholestatic jaundice/hepatic dysfunction with prior clarithromycin use.

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Transcatheter closure of moderate to large patent ductus arteriosus. A Three-year (2011-2013) Surveillance on Animal Bites and Victims Vaccination in the South of Khorasan-e-Razavi Province, Iran. Cell surface components of Leishmania: identification of a novel parasite lectin?. This paper reports on the development and evaluation of various probes consisting of silicon cantilevers with different types of tips made of platinum, ruthenium, chromium and conductive CVD diamond for probe-based ultrahigh density ferroelectric data storage. Coagulation factors as indicators of protein synthesis in chronic liver disease. Apolipoprotein E gene polymorphism and risk of type 2 diabetes and cardiovascular disease. The aim of this study was the expression of goose parvovirus capsid protein (VP3) and its epitopes in Escherichia coli cells. Fearful behavior, body size, and serum IGF-I levels in nervous and normal pointer dogs. Effect of container, vitrification volume and warming solution on cryosurvival of in vitro-produced bovine embryos. The analyses were performed according to the minimum requirements described in the USEPA 1613 method with some minor modifications.

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Effectiveness of a 24-hour induction period with DST and CsA in inducing long-term graft survival. Metastatic large-cell neuroendocrine prostate carcinoma: successful treatment with androgen deprivation therapy. A case of unresectable advanced pancreatic cancer treated by gemcitabine-based chemotherapy following cancer pain alleviation by low-dose matrix-type transdermal fentanyl. An extensive exclusion of all possible causes allowed a diagnosis of Tubulointerstitial Nephritis and Uveitis syndrome with caseating granuloma in bone marrow. Visual function in patients followed at a Veterans Affairs polytrauma network site: an electronic medical record review. Children may vary in the degree to which they are affected by JRA, and dentists should investigate JRA as a cause of these abnormalities or deformities. Functional characterization of orchardgrass endoplasmic reticulum-resident Hsp90 (DgHsp90) as a chaperone and an ATPase. Extensive development of vulnerable plaques as a pan-coronary process in patients with myocardial infarction: an angioscopic study.

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This study was conducted in 12 villages to determine malariometric indices and associated risk factors, during long and short rainy seasons, in an area with varying malaria transmission intensities in Korogwe district, Tanzania. The difficulty in the assessment of individual exposure is the main problem in evaluating the relationship between EMF exposure and adverse health effects in electric utility workers. Anti-recombinant delta-giardin was used to localize the native protein to the trophozoite ventral disk in both immunofluorescence and immunoelectron microscopy assays. Importantly, the developed FA-Au PENPs can be used as a nanoprobe for targeted CT imaging of FAR-expressing cancer cells in vitro and the xenografted tumor model in vivo. A detailed literature search was made in Medline for related research publications written in English. This comprehensive research will improve understanding of the safety of these treatments. A genechip profiling analysis identified several candidate genes to be up-regulated in NCoR1-deficient IEC. Methadone-maintained patients in primary care have higher rates of chronic disease and multimorbidity, and use health services more intensively than matched controls.

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Marrow transplantation following busulfan and cyclophosphamide for chronic myelogenous leukaemia in accelerated or blastic phase. These results suggest that brain activity during conscious REST is sustained by a large scale network of heteromodal associative parietal and frontal cortical areas, that can be further hierarchically organized in an episodic working memory parieto-frontal network, driven in part by emotions, working under the supervision of an executive left prefrontal network. Overall, the results indicate that the bacterial community of the MBR has flexibility in terms of its phylogenetic structure and metabolic activity to maintain the high wastewater treatment capability. Ulcerative dermatosis of the Shetland sheepdog and rough collie dog may represent a novel vesicular variant of cutaneous lupus erythematosus. In contrast, when neonatal growth standards were applied, the risks of spontaneous preterm delivery in intrauterine growth restriction, borderline intrauterine growth restriction, and large-for-gestational-age groups were significantly lower (odds ratios of 0.5, 0.7, and 0.7 for intrauterine growth restriction, borderline intrauterine growth restriction, and large-for-gestational-age groups, respectively) because of an underestimation in the number of fetuses with abnormal size at birth delivered prematurely.

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4 clinical decision rules combined with D-dimer testing each had high sensitivity and low specificity for excluding acute pulmonary embolism. In vitro and in vivo studies in different animal species have demonstrated a significant protective effect of vitamins C and E against light-induced cataract. We also discuss the evidence that NKT cells affect discrete differentiation events in the multistep process by which a naive B cell experiences antigen and develops into a memory B cell or an antibody-secreting plasma cell. Faecal occult blood testing is offered biennially to subjects aged 50-70. We traced this phenotype to disrupted germ-layer morphogenesis at the primitive streak. Midterm results after ventricular septation for double-inlet left ventricle in early infancy. The physical examination included measuring body mass index, waist circumference, muscle power, total fat amount, body fat percentage, and lean body mass.

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