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Clacine (Clarithromycin)

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Clacine is used for the treatment of various infections in the body like infections of the throat, sinus, skin, soft tissue, chest (infection of lungs and windpipe). It is also used in the treatment of ulcers in the intestine caused by bacteria known as helicobacter pylori. It is also used for pneumonia as well as for skin infections.

Other names for this medication:
Aeroxina, Bacterfin, Bremon, Ciclinil, Clabact, Clacee, Clarimax, Clarimed, Clarimycin, Clarithromycin, Claritrox, Claritt, Clariwin, Claromycin, Claron, Clarosip, Claryl, Clarytas, Clasine, Clathrocyn, Cleanomisin, Cleron, Clonocid, Emimycin, Euromicina, Geromycin, Helozym, Infex, Kalecin, Klabax, Klabet, Klarifor, Klarit, Klarithran, Klaritpharma, Kleromicin, Klonacid, Krobicin, Laromin, Maclar, Macrol, Odycin, Onexid, Quedox, Rocin, Uniklar, Veclam, Zeclaren

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Avelox, Sumycin, Omnicef, Keflex, Ilosone, Chloromycetin, Myambutol, Ceftin

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Also known as: Clarithromycin


Clacine is used to treat many different types of bacterial infections affecting the skin and respiratory system. Clacine is also used together with other medicines to treat stomach ulcers caused by Helicobacter pylori. Clacine fights bacteria in the body. Clacine is also known as Clarithromycin, Maclar, Klaricid, Klacid, Clarimac, Claribid.


The recommended daily dosage is 15 mg/kg/day divided every 12 hours for 10 days (up to the adult dose). Refer to dosage regimens for mycobacterial infections in pediatric patients for additional dosage information.

For the treatment of disseminated infection due to Mycobacterium avium complex (MAC), Clacine Filmtab and Clacine Granules are recommended as the primary agents. Clacine Filmtab and Clacine Granules should be used in combination with other antimycobacterial drugs (e.g. ethambutol) that have shown in vitro activity against MAC or clinical benefit in MAC treatment.

For treatment and prophylaxis of mycobacterial infections in adults, the recommended dose of Clacine is 500 mg every 12 hours.

For treatment and prophylaxis of mycobacterial infections in pediatric patients, the recommended dose is 7.5 mg/kg every 12 hours up to 500 mg every 12 hours.

Clacine therapy should continue if clinical response is observed. Clacine can be discontinued when the patient is considered at low risk of disseminated infection.


If you overdose Clacine and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Clacine overdosage: nausea, vomiting, diarrhea, abdominal discomfort.


Store Clacine XL Filmtab at 20 to 25 degrees C (68 to 77 degrees F). Excursions permitted to 15 to 30 degrees C (59 to 86 degrees F).

Side effects

The most common side effects associated with Clacine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Clacine if you are allergic to its components or to clarithromycin or to similar medicines such as azithromycin (Zithromax), dirithromycin (Dynabac), erythromycin (E.E.S., E-Mycin, Ery-Tab, Erythrocin), troleandomycin (Tao). Do not take Clacine if you're pregnant or you plan to have a baby, or you are a nursing mother. Do not take Clacine if you take astemizole (Hismanal), cisapride (Propulsid), ergot medicine such as ergotamine (Ergomar, Ergostat, Cafergot, Ercaf, Wigraine), or dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), pimozide (Orap), terfenadine (Seldane). Do not take Clacine if you have liver disease, kidney disease, myasthenia gravis, porphyria; personal or family history of "Long QT syndrome". Try to be careful with Clacine usage in case you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement. Avoid consuming alcohol. It can be dangerous to stop Clacine taking suddenly.

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Angiomyoma of the upper lip: report of a case with electron microscopic and immunohistochemical observation. Functional deglutition disorders: etiology, diagnosis and therapy. Plantarflexory base wedge osteotomy in the treatment of functional and structural metatarsus primus elevatus. In this prospective study, 67 healthy breeder-owned Chihuahuas were used. On the basis of our series, we agree with the international literature in affirming that, in cases of mycobacterial lymphadenopathy, a combined antibiotic and surgical therapy is necessary. Synthesis and characterization of DNA fenced, self-assembled SnO2 nano-assemblies for supercapacitor applications.

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Increased attention on the reporting of renal trauma demographics is necessary to improve detection of trends. The custom-fitted athletic mouthguard for the orthodontic patient and for the child with a mixed dentition. Here, we investigated the systems metabolic changes in the mouse upon S. The sodium and water retention causes suppression of renin release. The first 50 enrollees were scheduled for six follow-up visits, and remaining men were followed at Days 7 and 42. Sphingosine 1-phosphate (S1P), a lysophospholipid mediator, regulates diverse functions of many types of cells by binding to specific G protein-coupled receptors termed S1P(1)-S1P(5). Signs of glass ionomer-dentin interaction were evident by SEM analysis for Fuji II LC specimens.

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An enzyme-linked immunosorbent assay revealed that the levels of endothelin in endothelial cell conditioned media was also increased by TGF-beta 1. The authors present a case of liver tuberculoma as an occupational disease. The closure of the defect heals well within 4-6 weeks even in presence of scar tissue from multiple prior surgeries. LNX (Ligand of Numb-protein X) was originally isolated as a binding partner to the cell-fate Determinant Numb during development, and then identified to act as a RING finger-type E3 ubiquitin ligase for the ubiquitylation and degradation of Numb. In addition, relief from mechanical allodynia, induced by ICS exposure, was also observed at day 9 after the cessation of antidepressant treatment. Integrity of the upper part of the oral cavity is required for the effective pumping of amniotic fluid, the essential mode of nutrition in intrauterine life.

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Dental erosion in a group of British 14-year-old school children. Ultrasonographic findings in the gall bladder in human fascioliasis. However, for bipolar sex offenders with comorbid paraphilias, the drug may not be effective for paraphilic symptoms. Effects of the traditional Japanese medicine Tokaku-jyoki-to in rat-models for menopausal hot flash. Furthermore, DBPs formation pathways and mechanisms were suggested during chlorination and chloramination of chlorotoluron, ametryn, dinoseb L-tryptophan. Cox proportional hazards regression was used for the statistical analyses. Previous research has shown that loneliness is strongly associated with both physical and psychological ill health, particularly among adolescents. Local interleukin-10 production during respiratory syncytial virus bronchiolitis is associated with post-bronchiolitis wheeze. However, a surprisingly large body of both old and new studies suggests roles for actin filaments (F-actin) and myosins (F-actin-based motor proteins) in spindle assembly and function. We analyzed the preoperative diagnostics, surgical strategy and postoperative follow-up (duration: 12-168 months, mean 37.5) for functional morbidity and seizure outcome.

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A detailed study of possible triggering factors was performed in all patients. We retrospectively analyzed clinical data from 79 patients and evaluated the prognosis of patients with platinum-based adjuvant chemotherapy, recurrence patterns, patient response to chemotherapy or radiation therapy, and prognosis in patients who experienced relapse. If this finding is confirmed, clinicians should be aware about MetS diagnosis and treatment in overweight depressed patients, especially if outcome is not being satisfactory enough. In comparison with the situation in 1981, limits and regulations for mycotoxins have been expanded in 1987 with more countries having legislation (proposed or passed) on the subject, more products, and more mycotoxins covered by this legislation. The method has proved valuable for describing the evolution in different ischemic heart diseases. Mixed-lineage kinase 3 (MLK3) is a mitogen-activated protein kinase kinase kinase that activates multiple mitogen-activated protein kinase pathways and has been implicated in regulating proliferation in several cell types. Trypanosoma cruzi: the effect of variations in experimental conditions on the levels of macrophage infection in vitro. Rare cases in which there is a constitutional deletion of chromosomal band 13q14 permitted localization of the responsible gene. Increases in the valgus angle and moment of the knee joint and higher lateral gastrocnemius activity during the late period showed an association with ACL injury risk factors during side-cutting, and higher lateral gastrocnemius activity during the early period showed an association with injury risk factors during cross-cutting.

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Adipue and colleagues recently discovered that mice in their breeding colony spontaneously developed inflamed joints reminiscent of RA and may, therefore, have found a new model to examine pathogenic mechanisms and test new treatments for this human inflammatory disease. The common presentation with childhood hepatosplenomegaly in rural communities means that it is an important example of a multi-factorial disease and its association with severe and subtle morbidities underlies the need for well-designed public health strategies for tackling common infectious diseases in tandem rather than in isolation. To use a novel dynamic autoregulation analysis (dAR) to test the hypothesis that the optic nerve head (ONH) blood flow (BF) autoregulation is disrupted during early stages of experimental glaucoma (EG) in nonhuman primates. By focusing on molecular subnetworks, or modules, we show that module topology is tightly linked to the level of environmental variability (noise) the module expects to encounter. Physiology of meningeal innervation: aspects and consequences of chemosensitivity of meningeal nociceptors.

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Articles were assessed for study quality and specific information addressing the stated purpose. How fine-grained spatial analyses can help us understand navigation behavior and performance with maps. Subsequently, the miRNA target prediction and pathway enrichment analysis were carried out to find out the biological and functional relevant genes involved in the meta-signature miRNA regulation. In this study, we analyzed the 3D structure of ENPP4 and determined its tumoricidal effects on MCA207 cells. We are reporting a case of acute small bowel obstruction in a 40 year old Turkish male, 48 months following bilateral vagotomy and pyloroplasty. The half-life of inactive enzyme complexes varied from approximately 2 h (without D-alanine) to 4.5 days (with D-alanine). Furthermore, sumoylated ICE1 represses MYB15, which is a negative regulator of CBF3/DREB1A and freezing tolerance. There was, therefore, reason to check data from a study that reported high rates, and to review evidence in relation to diagnosis and outcome. The study was conducted by interviewing a Lancaster County, Pennsylvania, Old Order Amish family. The data were age-adjusted to the year 2000 Standard Population to determine 10-year hospitalization and mortality rate trends, which we stratified according to gender, age, and poisoning agent.

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Simultaneous determination of alpha-aminoadipic semialdehyde, piperideine-6-carboxylate and pipecolic acid by LC-MS/MS for pyridoxine-dependent seizures and folinic acid-responsive seizures. By contrast, both AT1 and AT2 receptors occur in the molecular layer of the cerebellum. Altogether, this study implicates this miRNA in the regulation by mesenchymal cells of surrounding lung epithelium, making it a potential key player during tissue injury. Two cases of bowel perforation associated with sunitinib treatment for renal cell carcinoma. The magnitude of P(p) depends on the transfer function, T(f), of the leaf cells.

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Radionuclides in some edible and medicinal macrofungal species from Tara Mountain, Serbia. Macrophages play a key role in the pathogenesis of NeuroAIDS, they are the main reservoirs of the infection in brain, promoting the inflammatory escalation, astrogliosis and degeneration process. Clinical significance of autoantibodies induced by infliximab treatment: two-year follow-up after infliximab discontinuation. Upper esophageal sphincter (UES) intrabolus pressure during sphincter opening was also greater in the older subjects. Root biomass increased from July to September and from January to March. Moreover, our method has an advantage over the classical one as it is easier, safer, faster, less expensive, and more consistent with good manufacturing practices to obtain large number of ADSCs ex vivo. This study shows that discontinuation of prophylactic antibiotics within 24 hours after colorectal surgery has no significant influence on the incidence of SSIs. Unexpectedly, the activity of squalene synthase from the other, sterol branch, was significantly decreased without, however, affecting ergosterol level. Therefore no relationship could be established between any of these activities and the ability of neutrophils to kill mycobacteria. This feature offers a prerequisite for in vivo screening as well as for dissecting the initiation or the postinitiation effect of ITCs and their conjugates during lung tumor development.

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Halogenated natural products (HNPs) are frequently detected in marine organisms. Each of the three complement pathways, can cleocin cause yeast infection classic, alternative, and lectin, has been implicated in the instigation of tissue pathology. The significant morbidity linked to epileptic encephalopathies of childhood has prompted the need to identify and dissect the factors and mechanisms that contribute to the resultant functional regression. Sustained increase in haemoglobin and RBC following long-term administration of recombinant human erythropoietin to patients with homozygous beta-thalassaemia. FoxM1, a critical regulator of oxidative stress during oncogenesis.

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On October 21, 2015, the Hawaii Department of Health (HDOH) was notified of a positive dengue immunoglobulin M (IgM) antibody result in a woman residing on Hawaii Island (also known as the Big Island). To gain a better understanding of the nature and extent of variation in functionally relevant regions of a polyploid genome, we developed a sequence capture assay to compare exonic sequences of allotetraploid wheat accessions. Grade II pielocalicial dilations with renal pelvis lesser than 15 mm can be echographically controlled without renal scan. This report summarizes both published and unpublished results of clinical trials with AmiKet. These findings underscore the complex interplay of cell cycle regulators in HPC, and demonstrate that loss of one can sometimes be compensated by loss of another CDKI in both, a pro- or anti-proliferative context. Thus, the prevention of SSIs must constitute a priority of nosocomial infections control in hospitals. Quality of life has been linked with the development of depression. All the patients were followed up, and the duration ranged from 5 months to 2 years, with an average of 1.2 years.

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Incidence of shoulder dystocia and related risk factors were analyzed and compared with controls. CdSe/ZnS quantum dots conjugated with a fluorescein derivative: a FRET-based pH sensor for physiological alkaline conditions. A severely deficient proposita with undetectable TC I levels displayed compound heterozygosity for two mutations, each causing a premature stop codon. We describe a simple and inexpensive modification to the Coulter 753 flow cytometer which enables simultaneous triple laser excitation for advanced multi-color analysis and sorting applications. This comparative study was conducted for three months at the Clinical Skills and Simulation Centre of the International Medical University in Malaysia. The results do not support the hypothesis of a strong association between coronary heart disease and Type 2 scores. A study of the heterogeneity of bacterial fluctuation-test data and the effects of auxotrophic-growth enhancement. The relationship between disability and health related quality of life (HRQL) is complex because of the role that function noroxin plays in the measurement, and certain points need to be dealt with in greater detail when the analysis is applied to the different dimensions of HRQL. Altogether, our data show that ubiquitination of SopB is not related to its intracellular stability but rather regulates its enzymatic activity at the plasma membrane and intracellular localization. Most cases of spontaneous cardiac rupture are due to myocardial infarction.

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Mislocalization of N-cadherin and zonula occludens-1, but not alpha- and beta-catenins, was observed after 14-3-3theta knockdown in Sertoli cells, moving from the cell-cell interface to cytosol, indicating a disruption of cell adhesion. Principles of ontogenetic research on the central nervous system. In sudden death, the resulting myocardial ischemia may precipitate fatal ventricular arrhythmias. Biochemical and genetic analysis of the Drk SH2/SH3 adaptor protein of Drosophila. CT-guided chemical rhizotomy of the C1 root for occipital neuralgia. Angiography and duplex carotid sonography (DCS) were repeated serially in each patient. Relationship between expression of voltage-dependent anion channel (VDAC) isoforms and type of hexokinase binding sites on brain mitochondria. At room temperature the binding was saturable, reached equilibrium at 2 h (using 20 pM endothelin), and was slowly and only partially reversed by unlabeled endothelin. Shorter time since ostomy creation, lack of religious practice, and lack of a partner negatively influenced the HRQOL of these patients.

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Single-dose lentiviral gene transfer for lifetime airway gene expression. This simulator is suitable for implementation on a cluster of general purpose graphical processing units (GPGPUs). We investigated the change in prescription error rates with the introduction of CPOE with and without a CDSS limited to weight-based dosing in a PICU. Seasonal affective disorder (SAD) is a subtype of recurrent depressive or bipolar disorder that is characterized by regular onset and remission of affective episodes at the same time of the year. The N-thiourea substituents, however, have no beneficial influence on the affinity. An exact equivalence between PI (Proportional-Integral) and two levaquin antibiotic po -parameter SPC (Simplified Predictive Control) is developed to provide identical control of first order linear plants. The data were analyzed by using the McNemar test and by determining the kappa agreement coefficient. Literature analysis revealed morphological disorders also in some clinical cases of patients with type 1 diabetes. Exercise training did not affect the elastic carotid artery, but improved vessel wall properties of the brachial, and maybe also of other, muscular large arteries. Also unlike the least squares approach, this formulation permits tests of the independence of measurement errors as well as the equality of measurement units.

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Since blood glucose levels increase during the acute phase response, we adjusted for elevated serum acute phase reactants. Relationships among facial type, buccolingual molar inclination, and cortical bone thickness of the mandible. Cases of CJD and MS were identified from the National Health Insurance Research Database from January 2000 to December 2005. Genome DNA of levaquin dose bacteremia recipients was extracted from pre-operative peripheral blood. The validity of this was investigated by a nationally distributed questionnaire.

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It succeeded to some extent in this objective but during the past decade in the United States, it has reverted into an organization primarily to protect the nuclear industry from liability resulting from radiation exposure. unfolded molecules are not obligatory intermediates in FGF2 secretion. In three experiments we examined whether amphetamine treatment (0-10 mg/kg per day) on postnatal days 11-17 altered the subsequent performance of adult Sprague-Dawley rats on a step-down passive avoidance, active avoidance, or novelty-seeking task. Characterization of Albright hereditary osteodystrophy and related disorders. Transcript levels of representative phenylpropanoid pathway genes were unchanged in transgenic plants, supporting a glycosylation-mediated redirection of phenylpropanoid carbon flow as opposed to enhanced phenylpropanoid pathway flux. On the basis of the algorithm for rapid evaluation of patients with an acute generalized vesiculopustular rash illness, our patient met criteria for high risk for smallpox. Compounds 2, 3, 5, and 8-10 were isolated from this genus for the first time, and compounds 1,4 were obtained from this plant for the first time.

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In order to ascertain the role of gene expression in cleavage arrest, we have examined the protein synthetic patterns of human pre-embryos which have undergone spontaneous cleavage arrest in vitro. O6-alkylguanine-DNA alkyltransferase in the chick embryo during development. Gastrodin improves cognitive dysfunction and decreases oxidative stress in vascular dementia rats induced by chronic ischemia. Variation in umami perception and in candidate genes for the umami receptor in mice and humans. In this article, the authors (a) describe a nonword repetition task, the Syllable Repetiton Task (SRT), that eliminates this confound and (b) report findings from 3 validity studies.

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