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Delos (Roxithromycin)
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Delos

Delos is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Delos is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring.

Other names for this medication:
Acevor, Aristomycin, Assoral, Azuril, Biaxsig, Bicofen, Cadithro, Delos, Dorolid, Elrox, Erybros, Macrolid, Makrodex, Monobac, Odonticina, Overal, Pedilid, Pedrox, Ramivan, Redotrin, Roksolit, Romyk, Rossitrol, Rotramin, Roxacine, Roxithromycine, Roxithromycinum, Roxitromicina, Rulid

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Ilosone, Amoxil, Floxin, Suprax, Cleocin, Vantin, Ceftin, Chloromycetin

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Also known as: Roxithromycin

Description

Each Delos tablet contains either 150mg or 300mg of the active ingredient roxithromycin. Each tablet also contains: hydroxypropylcellulose, poloxamer, povidone, colloidal anhydrous silica, magnesium stearate (470), purified talc (553), maize starch, hypromellose, anhydrous glucose, titanium dioxide (171), propylene glycol (1520). Delos does not contain gluten, sucrose, lactose, tartrazine or any other azo dyes.

Dosage

Take Generic Delos by mouth with food. If you have trouble swallowing the tablet whole, it may be crushed or chewed with a little water. Swallow Generic Delos tablets whole with a glass of water. Generic Delos should be taken at least 15 minutes before food or on an empty stomach (i.e. more than 3 hours after a meal). Generic Delos works best if you take it on an empty stomach. For treating bacterial infections, Generic Delos is usually taken for 5 to 10 days. If you want to achieve most effective results do not stop taking Generic Delos suddenly.

Overdose

Symptomatic treatment should be provided as required. There is no specific antidote.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Do not store in the bathroom. Keep in a tight, light-resistant container. Keep out of the reach of children.

Side effects

The most common side effects associated with Delos are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

The safety of roxithromycin has not been demonstrated in patients with impaired hepatic or renal function. Caution should be exercised if roxithromycin is administered to patients with impaired hepatic or renal function. If administered to patients with severe impaired hepatic function (eg. hepatic cirrhosis with jaundice and/or ascites), consideration should be given to reducing the daily dosage to half the usual dosage.

Prolonged or repeated use of antibiotics including roxithromycin may result in superinfection by resistant organisms. In the event of superinfection, roxithromycin should be discontinued and appropriate therapy instituted.

When indicated, incision, drainage or other appropriate surgical procedures should be performed in conjunction with antibiotic therapy.

Antibiotic associated pseudomembranous colitis has been reported with many antibiotics. A toxin produced by Clostridium difficile appears to be the primary cause. The severity of the colitis may range from mild to life threatening. It is important to consider this diagnosis in patients who develop diarrhoea or colitis in association with antibiotic use (this may occur up to several weeks after cessation of antibiotic therapy). Mild cases usually respond to drug discontinuation alone. However, in moderate to severe cases, appropriate therapy with a suitable oral antibacterial agent effective against Clostridium difficile should be considered. Fluids, electrolytes and protein replacement therapy should be provided when indicated.

Roxithromycin, like erythromycin, has been shown in vitro to elicit a concentration - dependent lengthening in cardiac action potential duration. Such an effect is manifested only at supra – therapeutic concentrations. Accordingly, the recommended doses should not be exceeded. In certain conditions macrolides, including roxithromycin, have the potential to prolong the QT interval. Therefore roxithromycin should be used with caution in patients with congenital prolongation of the QT interval, with ongoing proarrhythmic conditions (ie uncorrected hypokalemia or hypomagnesaemia, clinically significant bradycardia), and in patients receiving Class IA and III antiarrhythmic agents.

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With regard to the Family Health Strategy, in 2002 Sao Gabriel do Oeste was better off in three of the four indicators studied, however, this situation was reversed at the end of the period when the county was overtaken by Rio Verde de Mato Grosso in three of the four indicators analyzed, including, the monthly average community health worker visits per registered family, the main activity of a Family Health Strategy agent. A 360-degree overview of body composition in healthy people: relationships among anthropometry, ultrasonography, and dual-energy x-ray absorptiometry. In contrast to the chloroplast stroma, less attention has been paid to the thylakoid lumen, an inner, continuous space enclosed by the thylakoid membrane in which redox regulation is also essential for photosystem biogenesis and function. To provide useful data for establishing intraoperative thresholds, MDP was also expressed as a percentage of femoral head width to control for fluoroscopic magnification. Electrocardiographic and cardiac magnetic resonance imaging parameters as predictors of a worse outcome in patients with idiopathic dilated cardiomyopathy. Poor assessment of HIV epidemiology and occupational HIV transmission risk by medical students.

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Techno-thanatology: moral consequences of introducing brain criteria for death. Immunocytochemical demonstration of growth hormone in an acidophilic adenoma of the adenohypophysis in a cat. Diagnostic pitfalls and treatment delays in these patients are discussed. Outbreaks of equine influenza cause severe economic loses to the horse industry and consequently competition horses are required to be regularly vaccinated against equine influenza. Also, fast chemical exchange processes sumycin drug class result in small chemical shifts that appear to be related to local conformational changes.

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coli using the polymerase chain reaction (PCR) and a digoxigenin (DIG)-labelled DNA probe to facilitate the early detection and epidemiological analysis of these pathogens. It was suggested that mononitrocarbazole, which seemed to be weakly mutagenic, and dinitrocarbazole were readily formed by the reaction of carbazole with NO2, and that the other high-potency mutagens were formed by the photochemical reaction of carbazole with NO2 with irradiation by light. catarrhalis in comparison to strains that lacked beta-lactamase. This information would assist in assessing need for services on a locality basis. Results indicated that fatigue and pain were associated with salivary cortisol levels. This paper presents a design strategy for close-packing circular finite-conjugate optics to create a spherical focal surface. Moreover, in MCF-7Dox cells, blocking the activity of above kinases by specific inhibitors strongly reduced expression of MMP-2 and c-Jun, and suppressed invasion of the cells in vitro.

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