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Docofloxacine (Ofloxacin)

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Docofloxacine (brand names include: Onoff / Floxin / Floxstat / Ocuflox / Novecin / Oflo / Oflox / Taravid / Tarivid / Zanocin) belongs to a class of drugs known as fluoroquinolone antibiotics. Docofloxacine is used for the treatment of many bacterial infections, including bronchitis, pneumonia, uncomplicated skin and skin structure infections, gonorrhea, urethritis, cystitis, complicated urinary tract infections, and prostatitis. Docofloxacine can also be used for the treatment of travelers' diarrhea.

Other names for this medication:
Albact, Bactocin, Bioquil, Biravid, Danoflox, Docofloxacine, Dolocep, Drovid, Ecuflox, Ermofan, Ethiflox, Evaflox, Ofloxacin

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Vantin, Noroxin, Flagyl, Rulide, Cipro, Zithromax, Suprax, Avelox, Cefixime

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Also known as: Ofloxacin


Docofloxacine is an antibiotic useful for the treatment of a number of bacterial infections. When taken by mouth or injection into a vein this includes pneumonia, cellulitis, urinary tract infections, prostatitis, plague and certain types of infectious diarrhea. Other uses, along with other medications, include multidrug resistant tuberculosis. An eye drop may be used for a superficial bacterial infection of the eye and an ear drop may be used for otitis media when there is a hole in the ear drum.

When taken by mouth common side effects include vomiting, diarrhea, headache, and rash. Other serious side effect include tendon rupture, numbness due to nerve damage, seizures, and psychosis. Use in pregnancy is typically not recommended. Docofloxacine is in the fluoroquinolone family of medications. It works by interfering with the bacteria's DNA.


Docofloxacine is usually taken every 12 hours. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take this medicine with water, and drink extra fluids to keep your kidneys working properly.

Docofloxacine may be taken with or without food, but take it at the same time each day.

Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Docofloxacine will not treat a viral infection such as the flu or a common cold.

Do not share this medicine with another person, even if they have the same symptoms you have.

This medicine can cause you to have a false positive drug screening test. If you provide a urine sample for drug screening, tell the laboratory staff that you are taking Docofloxacine.

Store Docofloxacine at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.


Information on overdosage with Docofloxacine is limited. One incident of accidental overdosage has been reported. In this case, an adult female received 3 grams of Docofloxacine intravenously over 45 minutes. A blood sample obtained 15 minutes after the completion of the infusion revealed an Docofloxacine level of 39.3 µg/mL. In 7 h, the level had fallen to 16.2 µg/mL, and by 24 h to 2.7 µg/mL. During the infusion, the patient developed drowsiness, nausea, dizziness, hot and cold flushes, subjective facial swelling and numbness, slurring of speech, and mild to moderate disorientation. All complaints except the dizziness subsided within 1 h after discontinuation of the infusion. The dizziness, most bothersome while standing, resolved in approximately 9 h. Laboratory testing reportedly revealed no clinically significant changes in routine parameters in this patient.

In the event of an acute overdose, the stomach should be emptied. The patient should be observed and appropriate hydration maintained. Docofloxacine is not efficiently removed by hemodialysis or peritoneal dialysis.


Store Docofloxacine below 86 degrees F (30 degrees C). Store away from heat, moisture, and light. Store in a tightly closed container. Do not store in the bathroom. Keep Docofloxacine out of the reach of children and away from pets.

Side effects

The most common side effects associated with Docofloxacine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Docofloxacine (ofloxacin) is contraindicated in persons with a history of hypersensitivity associated with the use of ofloxacin or any member of the quinolone group of antimicrobial agents.

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