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Flagenase (Metronidazole)
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Flagenase

Flagenase is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis).

Other names for this medication:
Acuzole, Aldezole, Amevan, Avidal, Deflamon, Dirozyl, Dumozol, Entizol, Fladystin, Flegyl, Grinazole, Kilpro, Metrajil, Metren, Metrocream, Metroderme, Metrolag, Metronour, Metrozol, Micogyl, Nidazole, Nidazyl, Pharmaflex, Polibiotic, Rodogyl, Rosaced, Rosasol, Rozacrme, Stomorgyl, Tismazol, Trichazole, Tricozyl, Varizil

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Also known as: Metronidazole

Description

Generic Flagenase is created by pharmacy specialists to struggle with dangerous infections spread by bacteria (it can be protozoa or anaerobic bacteria). Target of Generic Flagenase is to control, ward off and terminate bacteria. Generic Flagenase acts as an anti-infection remedy. Generic Flagenase operates by killing bacteria which spreads by infection. Flagenase is also known as Metronidazole. Generic Flagenase and other antibiotics don"t treat viral infections (flu, cold and other). Generic Flagenase also does not help with vaginal yeast infection. Generic name of Generic Flagenase is Metronidazole. Brand names of Generic Flagenase are Protostat, Flagenase, Flagenase ER, Flagenase 375.

Dosage

In the Female. One-day treatment – two grams of Flagenase, given either as a single dose or in two divided doses of one gram each, given in the same day. Seven-day course of treatment – 250 mg three times daily for seven consecutive days. There is some indication from controlled comparative studies that cure rates as determined by vaginal smears and signs and symptoms, may be higher after a seven-day course of treatment than after a one-day treatment regimen.

The dosage regimen should be individualized. Single-dose treatment can assure compliance, especially if administered under supervision, in those patients who cannot be relied on to continue the seven-day regimen. A seven-day course of treatment may minimize reinfection by protecting the patient long enough for the sexual contacts to obtain appropriate treatment. Further, some patients may tolerate one treatment regimen better than the other.

Pregnant patients should not be treated during the first trimester In pregnant patients for whom alternative treatment has been inadequate, the one-day course of therapy should not be used, as it results in higher serum levels which can reach the fetal circulation.

When repeat courses of the drug are required, it is recommended that an interval of four to six weeks elapse between courses and that the presence of the trichomonad be reconfirmed by appropriate laboratory measures. Total and differential leukocyte counts should be made before and after re-treatment.

Overdose

Single oral doses of Flagenase, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Flagenase has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Flagenase overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.

Storage

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

Side effects

The most common side effects associated with Flagenase are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Psychotic Reaction with Disulfiram. Use of oral metronidazole is associated with psychotic reactions in alcoholic patients who were using disulfiram concurrently. Do not administer metronidazole to patients who have taken disulfiram within the last two weeks.

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