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Geloderm (Metronidazole)
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Geloderm

Geloderm is a medicine used to treat different types of bacterial and parasitic infections, including those that affect the skin, vagina, blood, heart, bone, stomach, liver, joints, nervous system, respiratory tract, and other areas of the body.

Other names for this medication:
Aldezol, Amrizole, Anaerobex, Anegyn, Asuzol, Biatron, Deflamon, Diazole, Elyzol, Filmet, Flagemed, Flagenase, Flazole, Flegyl, Gnostol, Gynoplix, Klont, Medamet, Metroderme, Metrolag, Metronid, Metronide, Metroson, Metrozol, Nidazea, Norzol, Novazole, Onida, Repligen, Rosazol, Rozagel, Rozamet, Tismazol, Trichodazol, Trichomonacid, Trichopol, Triconex, Unigyl, Vagilen, Vagizol, Vandazole, Zyomet

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Also known as: Metronidazole

Description

Geloderm (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Geloderm is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.

Dosage

In the Female. One-day treatment – two grams of Geloderm, given either as a single dose or in two divided doses of one gram each, given in the same day. Seven-day course of treatment – 250 mg three times daily for seven consecutive days. There is some indication from controlled comparative studies that cure rates as determined by vaginal smears and signs and symptoms, may be higher after a seven-day course of treatment than after a one-day treatment regimen.

The dosage regimen should be individualized. Single-dose treatment can assure compliance, especially if administered under supervision, in those patients who cannot be relied on to continue the seven-day regimen. A seven-day course of treatment may minimize reinfection by protecting the patient long enough for the sexual contacts to obtain appropriate treatment. Further, some patients may tolerate one treatment regimen better than the other.

Pregnant patients should not be treated during the first trimester In pregnant patients for whom alternative treatment has been inadequate, the one-day course of therapy should not be used, as it results in higher serum levels which can reach the fetal circulation.

When repeat courses of the drug are required, it is recommended that an interval of four to six weeks elapse between courses and that the presence of the trichomonad be reconfirmed by appropriate laboratory measures. Total and differential leukocyte counts should be made before and after re-treatment.

Overdose

If you overdose Generic Geloderm and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Geloderm overdosage: dizziness, seizures, torpor, retching, nausea, lack of balance, problems with coordination, tingling.

Storage

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

Side effects

The most common side effects associated with Geloderm are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Metronidazole is mainly metabolised by hepatic oxidation. Substantial impairment of Metronidazole clearance may occur in the presence of advanced hepatic insufficiency. The risk/benefit ratio of using Metronidazole to treat trichomoniasis in such patients should be carefully considered. Plasma levels of Metronidazole should be closely monitored.

Cases of severe hepatotoxicity/acute hepatic failure, including cases with a fatal outcome with very rapid onset after treatment initiation in patients with Cockayne syndrome have been reported with products containing metronidazole for systemic use. In this population, metronidazole should therefore be used after careful benefit-risk assessment and only if no alternative treatment is available. Liver function tests must be performed just prior to the start of therapy, throughout and after end of treatment until liver function is within normal ranges, or until the baseline values are reached. If the liver function tests become markedly elevated during treatment, the drug should be discontinued.

Patients with Cockayne syndrome should be advised to immediately report any symptoms of potential liver injury to their physician and stop taking metronidazole.

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Effects of the incorporation of CHAPS into SDS micelles on neuropeptide-micelle binding: separation of the role of electrostatic interactions from hydrophobic interactions. 2DE and 3DE studies were examined in 40 initial patients who were admitted for acutely decompensated heart failure. The specimen was manually morcellated within a Cook Lap Sac or Endocatch II bag under laparoscopic or direct observation. In contrast, the Coulombic contribution to the PMF becomes higher overall, making the mean force less attractive or more repulsive, with increasing pressure. Analysis and evaluation on the English translation of paradoxical treatments in Chinese medicine. With ensuring the performance of separation as the premise, using 100 nm diameter of the capillary increased the absorption intensity of signal detection, so the absorption peak can be detected in the range of ultraviolet and visible light wavelength.

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Characterization and gene cloning of a novel serine protease with nematicidal activity from Trichoderma pseudokoningii SMF2. The relationship between the glycoprotein defect and retinitis pigmentosa remains to be established. For several decades vitamin K antagonists (VKA) were the standard for stroke prevention in atrial fibrillation. A questionnaire was used to elicit responses from the respondents, containing 11 modified items. Photoreceptor plasticity in the albino rat retina following unilateral optic nerve section. In vitro effects of ethanol and acetaldehyde on lymphoid cells as determined by 31P NMR spectroscopy. Both A and g(s) were positively correlated for each species, but A and g(s) were generally not correlated with psi(pd), psi(md) or delta psi(pd-md). The tyrosinase mRNA levels were not always correlated with tyrosinase activity, i.e., TPA down-regulated, dbcAMP upregulated, while linoleic acid or palmitic acid did not alter the message levels, indicating that fatty acid regulation of melanogenesis was due to post-transcriptional events. Due to their ability to induce strong cell-mediated immunity (CMI) in addition to antibodies, viral vectors may be suitable for infectious agents, such as malaria parasites, where potent CMI is required for protection. Combination of voice therapy and antireflux therapy rapidly recovers voice-related symptoms in laryngopharyngeal reflux patients.

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Serum concentrations of 8-iso-PGF2alpha and vitamins C and E did not differ between cases and controls. Stability of fusarin C: effects of the normal cooking procedure used in China and pH. Validation of a polymerase chain reaction method for the detection of rendered bovine-derived materials in feedstuffs. Quantifying the spatio-temporal epidemiology of dengue in large cities within the context of a Geographic Information System is a first step in the identification of socio-economic risk factors. Left vagus nerve stimulation suppresses experimentally induced pain. Similarly, tacrolimus is also capable of blocking the glucose-stimulated secretion of insulin by MIN6 cells. After successful removal of the DCA device, an early occlusion of the coronary vessel occurred, which could be successfully treated by perfusion balloon catheter. The structure of chromatin is critical for many aspects of cellular physiology and is considered to be the primary medium to store epigenetic information.

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Intense mRNA expression was detected in the liver and testis but not in other organs by ribonuclease protection assay. Patient and public involvement (PPI) is seen as a way of helping to shape health policy and ensure a patient-focused health-care system. Sequence analysis revealed that one patient was infected with Cryptosporidium hominis whereas the remaining eight patients were infected with C. Intelligence is negatively associated with the number of FSS in the general population. Many clinicians now speculate that this entity is underreported due to misdiagnosis. Associations between deprived life circumstances, wellbeing and self-rated health flagyl dosing instructions in a socially marginalized population. We also collected data from their teachers and fathers or mothers.

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