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Ginerella (Metronidazole)
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Ginerella

Ginerella belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

Other names for this medication:
Amebidal, Aminidazole, Amobin, Amrizole, Anerobia, Biozyl, Colpofilin, Elyzol, Flazole, Florazole, Grinazole, Gynotran, Medamet, Menizol, Metrolyl, Metronour, Nidazea, Nidazol, Nizole, Orogyl, Padet, Repligen, Rhodogil, Supplin, Torgyl, Trichozole, Venogyl, Vertisal

Similar Products:
Cefixime, Noroxin, Cipro, Biaxin, Chloromycetin, Rulide, Sumycin, Ilosone, Omnicef

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Also known as: Metronidazole

Description

Ginerella (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Ginerella is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.

Dosage

When repeat courses of the drug are required, it is recommended that an interval of four to six weeks elapse between courses and that the pres- ence of the trichomonad be reconfirmed by appro- priate laboratory measures. Total and differential leukocyte counts should be made before and after re-treatment.

Overdose

Single oral doses of Ginerella, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Ginerella has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Ginerella overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.

Storage

Store Ginerella at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Ginerella out of the reach of children and away from pets.

Side effects

The most common side effects associated with Ginerella are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Metronidazole should be used with caution in patients with active disease of the Central Nervous System. The treatment should be withdrawn in case of ataxia, dizziness, or confusion. The risk of aggravation of the neurological state should be considered in patients suffering from severe central and peripheral neurological diseases, fixed or progressive paraesthesia and epilepsy. Caution is required in patients with active disease of the central nervous system except for brain abscess.

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Effect of aneurysmal subarachnoid hemorrhage on word generation. Application of a clustering-based peak alignment algorithm to analyze various DNA fingerprinting data. No significant difference was observed for all these parameters between patients and controls, although PBMC displayed a clear macroautophagy induction following exposure to rapamycin and lithium. Long-term results of plastic reconstructions in acquired aortic valvular disease. Long-term results of interferential current stimulation in the treatment of bladder instability.

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Transfection of HUVEC with JNK1 dominant negative (DN-JNK1) prevented the TB-induced increases of p21 and p53 protein level and decrease of DNA synthesis, suggesting that JNK1/2 activation is involved in the TB-induced cell cycle arrest in HUVEC. The latter has been shown to compromise accurate photo-optical measurement of fibrinogen. Growing evidence shows that trafficking of the mu-opioid receptor (MOR) is a critical process in functional recovery from desensitization following activation and plays important roles in morphine tolerance and dependence largely because of the failure of morphine to promote such trafficking. The results of this exploratory analysis seem to suggest that male patients do not respond to IFNbeta treatment in the same way of females. Reversible cyclosporine-induced cortical blindness in allogeneic bone marrow transplant recipients. Using published data on screening sensitivity and intrapartum prophylaxis effectiveness, we estimated the potential reduction in cases under optimal prevention implementation. Posterior polymorphous membranous dystrophy with overlapping features of iridocorneal endothelial syndrome.

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