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Loxin (Levofloxacin)

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Loxin is a fluoroquinolone (flor-o-KWIN-o-lone) antibiotic that fights bacteria in the body. Loxin is used to treat different types of bacterial infections. Loxin is also used to treat people who have been exposed to anthrax or certain types of plague.

Other names for this medication:
Alevokem, Anlev, Evabit, Evonex, Lefex, Lefloxin, Letab, Levobact, Levoflox, Levoking, Levonidin, Levonix, Levoquinol, Levozine, Livacin, Medibiox, Prixar, Prolecin, Quantrum, Quinix, Reskuin, Tivanik, Truxa, Ultraquin, Volox

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Rulide, Cipro, Duricef, Noroxin, Avelox, Cefixime, Omnicef, Suprax

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Also known as: Levofloxacin


To reduce the development of drug-resistant bacteria and maintain the effectiveness of Loxin and other antibacterial drugs, Loxin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Loxin Tablets/Injection and Oral Solution are indicated for the treatment of adults (≥18 years of age) with mild, moderate, and severe infections caused by susceptible strains of the designated microorganisms in the conditions listed in this section. Loxin Injection is indicated when intravenous administration offers a route of administration advantageous to the patient (e.g., patient cannot tolerate an oral dosage form).


The usual dose of Loxin Tablets or Oral Solution is 250 mg, 500 mg, or 750 mg administered orally every 24 hours, as indicated by infection and described in Table 1. The usual dose of Loxin Injection is 250 mg or 500 mg administered by slow infusion over 60 minutes every 24 hours or 750 mg administered by slow infusion over 90 minutes every 24 hours.


Overdose of the drug should be strictly avoided and if anyone has accidentally taken the overdose of the drug, then the victim should be provided with emergency medical help. Overdose victim can also consult to their local poison helpline. Some of the overdose symptoms include loss of coordination, drooping eyelids, weakness, decreased activity, trouble breathing, sweating, tremors, or seizure.

Side effects

The most common side effects associated with Loxin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Risk of tendinitis and tendon rupture is increased. This risk is further increased in older patients usually over 60 years of age, in patients taking corticosteroids, and in patients with kidney, heart and lung transplants. Discontinue if pain or inflammation in a tendon occurs.

Anaphylactic reactions and allergic skin reactions, serious, occasionally fatal, may occur after first dose.

Hematologic (including agranulocytosis, thrombocytopenia), and renal toxicities may occur after multiple doses.

Hepatotoxicity: Severe, and sometimes fatal, hepatoxicity has been reported. Discontinue immediately if signs and symptoms of hepatitis occur.

Central nervous system effects, including convulsions, anxiety, confusion, depression, and insomnia may occur after the first dose. Use with caution in patients with known or suspected disorders that may predispose them to seizures or lower the seizure threshold.

Clostridium difficile-associated colitis: evaluate if diarrhea occurs.

Peripheral neuropathy: discontinue if symptoms occur in order to prevent irreversibility.

Prolongation of the QT interval and isolated cases of torsade de pointes have been reported. Avoid use in patients with known prolongation, those with hypokalemia, and with other drugs that prolong the QT interval.

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Primary and immortalised human brain endothelial cells (BECs) represent two suitable options for studying P-gp function in vitro. An explanation for persistent bacteriuria in this population could be that periurethral E. Effects of environmental conditions on the psychological well-being of primates: a review of the literature. IAP inhibited lymphocyte responses to phytohemagglutinin in a can levaquin treat a sinus infection dose-dependent manner. At the same time, concentration of Met-enkephalin in myocardium was increased in the acute ischemia independently on the effect of fibrillation. The importance of these interactions to plant growth and development makes it likely that they will figure more prominently at future symposia.(ABSTRACT TRUNCATED AT 250 WORDS). Comparisons of patient and physician evaluations showed that physicians seem to be successful in building relationships on the affective level, but less successful on the instrumental level (i.e.

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