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Macrol (Clarithromycin)

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Macrol belongs to the class of medicines known as macrolide antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

Other names for this medication:
Cidoclar, Clacine, Clarimac, Clarimycin, Claritab, Clariva, Clarix, Claromycin, Claron, Clathrocyn, Clatic, Clonocid, Clormicin, Eliben, Emimycin, Euromicina, Fromilid, Karid, Karin, Klarifor, Klerimed, Kleromicin, Kofron, Lekoklar, Maclar, Mononaxy, Monozeclar, Onexid, Quedox, Rolicytin, Synclar, Taclar, Uniklar

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Chloromycetin, Ilosone, Biaxin, Ceftin, Amoxil, Floxin, Avelox, Terramycin, Duricef

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Also known as: Clarithromycin


Macrol (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac / Claribid) is used to treat many different types of bacterial infections affecting the skin and respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis (inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.

It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.

It also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Macrol works by stopping the growth of or killing sensitive bacteria by interfering with their protein synthesis.


Macrol Filmtab and Macrol Granules may be given with or without food.

Macrol XL Filmtab should be taken with food. Swallow Macrol XL Filmtab whole; do not chew, break or crush Macrol XL Filmtab.

Triple therapy: Macrol Filmtab/lansoprazole/amoxicillin. The recommended adult dosage is 500 mg Macrol Filmtab, 30 mg lansoprazole, and 1 gram amoxicillin, all given every 12 hours for 10 or 14 days.

Triple therapy: Macrol Filmtab/omeprazole/amoxicillin. The recommended adult dosage is 500 mg Macrol Filmtab, 20 mg omeprazole, and 1 gram amoxicillin; all given every 12 hours for 10 days. In patients with an ulcer present at the time of initiation of therapy, an additional 18 days of omeprazole 20 mg once daily is recommended for ulcer healing and symptom relief.

Dual therapy: Macrol Filmtab/omeprazole. The recommended adult dosage is 500 mg Macrol Filmtab given every 8 hours and 40 mg omeprazole given once every morning for 14 days. An additional 14 days of omeprazole 20 mg once daily is recommended for ulcer healing and symptom relief.


If you overdose Macrol and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Macrol overdosage: nausea, vomiting, diarrhea, abdominal discomfort.


Store Macrol XL Filmtab at 20 to 25 degrees C (68 to 77 degrees F). Excursions permitted to 15 to 30 degrees C (59 to 86 degrees F).

Side effects

The most common side effects associated with Macrol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Macrol if you are allergic to its components or to clarithromycin or to similar medicines such as azithromycin (Zithromax), dirithromycin (Dynabac), erythromycin (E.E.S., E-Mycin, Ery-Tab, Erythrocin), troleandomycin (Tao). Do not take Macrol if you're pregnant or you plan to have a baby, or you are a nursing mother. Do not take Macrol if you take astemizole (Hismanal), cisapride (Propulsid), ergot medicine such as ergotamine (Ergomar, Ergostat, Cafergot, Ercaf, Wigraine), or dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), pimozide (Orap), terfenadine (Seldane). Do not take Macrol if you have liver disease, kidney disease, myasthenia gravis, porphyria; personal or family history of "Long QT syndrome". Try to be careful with Macrol usage in case you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement. Avoid consuming alcohol. It can be dangerous to stop Macrol taking suddenly.

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