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Maczith (Azithromycin)
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Maczith

Maczith can be used for the treatment of throat infection and typhoid infection. It contains azithromycin which is used to treat a wide variety of bacterial infections.

Other names for this medication:
Azenil, Azicin, Azifast, Azigram, Azinil, Azinix, Azinom, Azitromicina, Azomac, Azycyna, Cinalid, Inedol, Odazyth, Oranex, Orobiotic, Rarpezit, Ricilina, Tanezox, Texis, Tromic, Tromix, Ultreon, Zaret, Zedd, Zibac, Zifin, Zirocin, Zithromac, Zitroken, Zitrolab, Zival

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Also known as: Azithromycin

Description

Maczith (Maczith tablets and Maczith for oral suspension) contain the active ingredient azithromycin, a macrolide antibacterial drug, for oral administration. Maczith has the chemical name (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl) oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. Maczith is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring. Its molecular formula is C38H72N2O12, and its molecular weight is 749.00.

Maczith, as the dihydrate, is a white crystalline powder with a molecular formula of C38H72N2O12∙2H2O and a molecular weight of 785.0.

Maczith is supplied as tablets containing azithromycin dihydrate equivalent to either 250 mg or 500 mg azithromycin and the following inactive ingredients: dibasic calcium phosphate anhydrous, pregelatinized starch, sodium croscarmellose, magnesium stearate, sodium lauryl sulfate, hypromellose, lactose, titanium dioxide, triacetin, and D&C Red #30 aluminum lake.

Maczith for oral suspension is supplied in bottles containing azithromycin dihydrate powder equivalent to 300 mg, 600 mg, 900 mg, or 1200 mg azithromycin per bottle and the following inactive ingredients: sucrose; sodium phosphate, tribasic, anhydrous; hydroxypropyl cellulose; xanthan gum; FD&C Red #40; and spray dried artificial cherry, creme de vanilla, and banana flavors. After constitution, each 5 mL of suspension contains 100 mg or 200 mg of azithromycin.

Dosage

Use Maczith as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Maczith is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Maczith at home, a health care provider will teach you how to use it. Be sure you understand how to use Maczith. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.

Do not use Maczith if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.

Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.

o clear up your infection completely, use Maczith for the full course of treatment. Keep using it even if you feel better in a few days.

Ask your health care provider any questions you may have about how to use Maczith.

Overdose

If you take an overdose of Maczith you should visit your doctor or health care provider immediately. Symptoms of Maczith overdosage include discomfort in the stomach, diarrhea, retching and nausea.

Storage

Store Maczith below 86 degrees F (30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Maczith out of the reach of children and away from pets.

Side effects

The most common side effects associated with Maczith are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Maczith is contraindicated in patients with known hypersensitivity to azithromycin, erythromycin, any macrolide or ketolide drug.

Maczith is contraindicated in patients with a history of cholestatic jaundice/hepatic dysfunction associated with prior use of azithromycin.

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