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Medamet (Metronidazole)
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Medamet

Medamet is a medicine used to treat different types of bacterial and parasitic infections, including those that affect the skin, vagina, blood, heart, bone, stomach, liver, joints, nervous system, respiratory tract, and other areas of the body.

Other names for this medication:
Acuzole, Amevan, Amodis, Buccoval, Cresac, Farnat, Flagolin, Litagyl, Menizol, Metrajil, Metris, Metrolotion, Metrolyl, Metronex, Metronidazole, Metropast, Metrosa, Metrosept, Padet, Pharmaflex, Rozacrme, Servizol, Suanatem, Trichomonacid, Trichopol, Vagimid, Vagizol, Vandazole

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Cipro, Terramycin, Myambutol, Suprax, Keflex, Duricef, Omnicef, Flagyl

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Also known as: Metronidazole

Description

Generic Medamet is created by pharmacy specialists to struggle with dangerous infections spread by bacteria (it can be protozoa or anaerobic bacteria). Target of Generic Medamet is to control, ward off and terminate bacteria. Generic Medamet acts as an anti-infection remedy. Generic Medamet operates by killing bacteria which spreads by infection. Medamet is also known as Metronidazole. Generic Medamet and other antibiotics don"t treat viral infections (flu, cold and other). Generic Medamet also does not help with vaginal yeast infection. Generic name of Generic Medamet is Metronidazole. Brand names of Generic Medamet are Protostat, Medamet, Medamet ER, Medamet 375.

Dosage

The dosage regimen should be individualized. Single-dose treatment can assure compliance, especially if administered under supervision, in those patients who cannot be relied on to con- tinue the seven-day regimen. A seven-day course of treatment may minimize reinfection by pro- tecting the patient long enough for the sexual con- tacts to obtain appropriate treatment. Further, some patients may tolerate one treatment regi- men better than the other.

Overdose

Single oral doses of Medamet, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Medamet has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Medamet overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.

Storage

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

Side effects

The most common side effects associated with Medamet are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Metronidazole is mainly metabolised by hepatic oxidation. Substantial impairment of Metronidazole clearance may occur in the presence of advanced hepatic insufficiency. The risk/benefit ratio of using Metronidazole to treat trichomoniasis in such patients should be carefully considered. Plasma levels of Metronidazole should be closely monitored.

Cases of severe hepatotoxicity/acute hepatic failure, including cases with a fatal outcome with very rapid onset after treatment initiation in patients with Cockayne syndrome have been reported with products containing metronidazole for systemic use. In this population, metronidazole should therefore be used after careful benefit-risk assessment and only if no alternative treatment is available. Liver function tests must be performed just prior to the start of therapy, throughout and after end of treatment until liver function is within normal ranges, or until the baseline values are reached. If the liver function tests become markedly elevated during treatment, the drug should be discontinued.

Patients with Cockayne syndrome should be advised to immediately report any symptoms of potential liver injury to their physician and stop taking metronidazole.

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