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Metazole (Metronidazole)

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Metazole is an antibiotic and antiprotozoal medication. It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis.

Other names for this medication:
Amevan, Aminidazole, Amodis, Amrizole, Anaerobex, Anerozol, Bemetrazole, Corsagyl, Efloran, Flagicure, Flanizol, Flegyl, Fortagyl, Ginerella, Gynoplix, Mecozol, Medamet, Menizol, Metco, Metrobac, Metrocev, Metrocreme, Metroderme, Metronex, Metronidazole, Metronide, Metronour, Metrosa, Metrozol, Metsina, Monizole, Nidagyl, Nipazol, Nizole, Noritate, Norzol, Protogyl, Repligen, Rosazol, Rovamet, Servizol, Supplin, Torgyl, Trichopol, Trichostatic, Trikozol, Vagilen, Vagizol, Vandazole, Varizil

Similar Products:
Chloromycetin, Rulide, Omnicef, Floxin, Biaxin, Flagyl, Vantin, Levaquin

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Also known as: Metronidazole


Generic Metazole is created by pharmacy specialists to struggle with dangerous infections spread by bacteria (it can be protozoa or anaerobic bacteria). Target of Generic Metazole is to control, ward off and terminate bacteria. Generic Metazole acts as an anti-infection remedy. Generic Metazole operates by killing bacteria which spreads by infection. Metazole is also known as Metronidazole. Generic Metazole and other antibiotics don"t treat viral infections (flu, cold and other). Generic Metazole also does not help with vaginal yeast infection. Generic name of Generic Metazole is Metronidazole. Brand names of Generic Metazole are Protostat, Metazole, Metazole ER, Metazole 375.


The usual adult oral dosage is 7.5 mg/kg every six hours (approx. 500 mg for a 70-kg adult). A maximum of 4 g should not be exceeded during a 24-hour period.

The usual duration of therapy is 7 to 10 days; however, infections of the bone and joint, lower respiratory tract, and endocardium may require longer treatment.

Patients with severe hepatic disease metabolize metronidazole slowly, with resultant accumulation.


Single oral doses of Metazole, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Metazole has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Metazole overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.


Store at room temperature below 25 degrees C (77 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Metazole are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Psychotic Reaction with Disulfiram. Use of oral metronidazole is associated with psychotic reactions in alcoholic patients who were using disulfiram concurrently. Do not administer metronidazole to patients who have taken disulfiram within the last two weeks.

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The ability of exogenously added laminin and fibronectin to enhance hatching and matrix metalloproteinase-2 expression was quantitated also. To test the hypothesis, mice were administered recombinant M-CSF or IL-6 intraperitoneally. Antithrombotic effects of ionic and non-ionic contrast media in nonhuman primates. We found that parvocellular (P) cells (the more numerous and color-sensitive pathway) showed response adaptation with a time constant on the order of tens of seconds and that their response after the removal of a visual stimulus lasting 1 min was similar in amplitude and time course to the response evoked by the photographic negative stimulus. Respondents were allocated randomly to three of the 25 health states and answered questionnaires by standard gamble (SG) and time trade-off (TTO) methods.

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On the other hand, there was only one relationship between occlusal factors and abnormal passive mandibular border positions. Research investigating the presence and acuity of metabolic, psychological, and vasomotor symptoms among perimenopausal women with HIV is limited. Here, we show that elevation of cAMP levels by forskolin inhibited ATO-mediated apoptosis in APL-derived NB4 cells, and this inhibition could be averted by cell permeable cAMP-dependent protein kinase inhibitor (14-22) amide. Moreover, a logarithmic regression model accurately predicted both measures. Prognosis after PVD procedures is poor, and providers should be aware that risk factors for PVD procedures may differ by diabetes status.

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Because of its convenience to use, patch may be the first choice in a general practice setting while gum may prove more effective in a cessation clinic setting where more time and experience is available. All people who wanted to know were posttest-counseled and informed of their results with referral to local clinical services if found to be HIV-positive. The pattern of contact changed, with hindpaw stance being shifted towards more distal elements while in the forepaw a reduction in the deployment of proximal elements without any compensating increase in distal contact was seen. atheromatous occlusion at the orifice of large caliber penetrating arteries termed branch atheromatous disease (BAD) and 2. Foreign body in the kidney: a case report and a review of the Japanese literature.

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Gender is a significant factor in determining the susceptibility to and severity of pulmonary diseases in both humans and animals. Seven VNTR loci were selected from the preliminary screening to expand the analysis, and the 7 VNTR loci had grouped 104 of S.enteritidis isolates into either 16 MLVA subtypes or 22 PFGE subtypes, with the D value at 0.7222 and 0.7974, respectively. As processing resources are limited, sustained analysis of the triggering problem reduces the ability to concentrate on other things. Pretreatment of the melanoma lines with the proteasome inhibitor N-acetyl-L-leucinyl-L-leucinyl-L-norleucinal (LLnL), which is known to inhibit activation of NF-kappaB, was shown to markedly increase apoptosis in 10 of 12 melanoma lines with death receptors for TRAIL. However, from the results obtained it can not be concluded whether or not pain sensitivity occurred in the animals. Cholesterol granulomas arise scarcely within the middle ear cavities revealed by a conductive deafness. With only 3 weeks for planning, a Biological Surveillance Initiative (BSI) was developed and implemented for a U.S. A truncated PKC1 gene encoding only the predicted catalytic domain of Pkc1p was able to complement pkc1 mutant strains. This shift towards fat synthesis was also observed in adipose tissue. The R(2) values for the ANN model corresponding to testing and training parameters showed a higher accuracy of prediction than equations established by the MLR method.

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In addition, the system can employ some newly developed software packages. Femoral neck and iliac bone histomorphometry in femoral neck fracture. ATP-binding cassette transporter A1 (ABCA1) functions as a cholesterol efflux regulatory protein. Potentiation of convergent synaptic inputs onto pyramidal neurons in somatosensory cortex: dependence on brain wave frequencies and NMDA receptor subunit composition. Older persons represent the fastest growing segment of individuals with visual impairments in industrialized countries. Results indicate that primordial germ cell progenitors do not express TNAP prior to gastrulation although at earlier times TNAP expression is found in an extraembryonic lineage destined to form the chorion. In two patients with chronic unilateral massive pulmonary embolism, we studied the pulmonary epithelial permeability by measuring the clearance of inhaled and deposited 99mTc-DTPA aerosol. In six conditioned suppression studies with rats, the authors demonstrate that two cues trained apart can each interfere with the potential of the other to predict the outcome. The increase in the number of recessive mutant alleles would be much slower and take many generations to reach the new equilibrium level.

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The Techniques Group of the Spanish Society of Pediatric Pneumology undertook to design recommendations for a rational approach to oxygen therapy, reviewing the existing literature in order to establish its indications, benefits and potential risks as well as its cost-effectivenes. Reduced brain serotonin (5-HT) activity has been linked to impulsive and violent forms of aggression for decades. Confirmation of a relationship of breast cancer risk with plasma insulin levels, on the one hand, or with total plasma IGF-I, on the other hand, could open up new perspectives for breast cancer prevention, either by changes in dietary intake patterns and physical activity, or by the use of certain chemopreventive drugs. The normal limits of all clinically relevant ECG measurements were determined for nine age groups. Importantly, this neoplastic profile was evident in nonneoplastic mucosa, suggesting that the identified genes may represent markers preceding cancer. Specifically, translating improved forced expiratory volume into meaningful clinical outcomes remains challenging.

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Maintained expansion will act as a stent reducing secondary contracture of the grafted-areas. The ANF-C receptor is not linked to adenylyl cyclase inhibition in bovine pulmonary artery endothelial cells. Synthesis, characterization, crystal structures and biological activity of set of Cu(II) benzothiazole complexes: artificial nucleases with cytotoxic activities. Ionic liquid-based homogeneous liquid-liquid microextraction for the determination of antibiotics in milk by high-performance liquid chromatography. The case of a man with resistant life-threatening ventricular arrhythmias who responded favorably to dl-sotalol, but developed worsening of underlying bronchospastic lung disease, is presented. Enhancement of local bone remodeling in osteoporotic rabbits by biomimic multilayered structures on Ti6Al4V implants. Long-term aircraft noise exposure and body mass index, waist circumference, and type 2 diabetes: a prospective study. In non-polarised cells, VacA alters the endocytic pathway, resulting in the release of acid hydrolases and the reduction of both extracellular ligand degradation and antigen processing. Use of the new World Health Organization child growth standards to describe longitudinal growth of breastfed rural Bangladeshi infants and young children.

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Psychological criteria for treating children with idiopathic short stature. The training included: identification of STDs, use of flow charts, patient education and counseling, clinic management issues and record keeping and reporting. Reflectance confocal microscopy (RCM) provides real-time noninvasive imaging of cell structure and may be useful in diagnosing lentigo maligna (LM). Modified Z-N is a sensitive and rapid method which can explore the gravity of this infection even further if used routinely and may control morbidity and mortality associated with this infection. Synergism in the autonomic regulation of parotid secretion of protein in sheep. Chronic ankle joint instability often necessitates operative treatment. After a brief introduction to converting a Boolean control network to an equivalent discrete-time bilinear dynamical system via the semi-tensor product of matrices, the system is split into a finite number of subsystems (constructed forest) with no time delays by using the idea of splitting time that is proposed in this brief. We undertook a systematic review and meta-analysis to compare morbidity associated with these 2 techniques. Sixty-one patients referred to a concussion clinic following mild traumatic brain injury. A form of phosphofructokinase (PFK) from Ascaris suum desensitized to hysteresis in the reaction time course and ATP allosteric inhibition has been used to study the activation by fructose 2,6-bisphosphate (F26P2) at varied pH in both reaction directions.

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Dirofilaria immitis: an emerging parasite in dogs, red foxes and golden jackals in Hungary. The procedure involves mobilization of strictured urethra and laying it open with a dorsal slit. The effect of diabetes on periaqueductal gray matter (PAG) stimulation-produced analgesia (SPA) was examined in rats. Malignancy cases in HIV-positive patients in Lodz region cleocin vaginal ovules dosing in years 1992-2010. The pathogenesis of liver damage in such subjects remains obscure. Insulin regulation of lipoprotein lipase activity in 3T3-L1 adipocytes is mediated at posttranscriptional and posttranslational levels. The results indicated that this promoter drove expression of the PyGUS gene efficiently in all examined algae, whereas there was quite low expression of PyGUS by the cauliflower mosaic virus 35S promoter that is widely used as a heterologous promoter in the transformation of green land plants. Cholestasis and jaundice are common after hematopoietic cell transplantation and may have multiple causes. The final volume of a cerebral infarct is important as it correlates with the morbidity and mortality associated with non-lacunar ischemic strokes. It thus appears that P3H1 deficiency leads to decreased deposition of extracellular matrix by osteoblasts and increased incorporation of mineral into the matrix.

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To evaluate quantitatively the effect of semi-fixed Twin-block appliance on the temporomandibular joint remodeling during the Class II malocclusion treatment. Biomechanical study of the edge outgrowth phenomenon of encapsulated chondrocytic isogenous groups in the surface layer of hydrogel scaffolds noroxin medicine for cartilage tissue engineering. Injected in equal amounts, rhBDNF and recombinant human NGF had quantitatively different effects on the cholinergic neurons. Irbesartan reduced body and white adipose tissue weights, improved glucose metabolism and vascular function in the aorta. Increased exogenous arginine or citrulline resulted in a significant increase in NO production and complete clearance of the parasites by activated macrophages. All three mutant receptors, TSHR-CS5 (Gln290), TSHR-CS6 (Gln291), and TSHR-CS7 (Gln291, Gln293) bound TSH with an affinity similar to that of wild type, and none of these amino acid substitutions prevented proteolytic cleavage of the extracellular domains of the TSHR. SCR non-responding was more frequent in both schizophrenics and depressives than in normal controls, while only the schizophrenics displayed excessive FPAR non-responding. Induced expression yielded a protein product that precipitated as an inclusion body in E. The sonic hedgehog gene may have regulatory functions in the signaling of the cascade of events that leads to axial elongation and vitreous enlargement of the eye under myopic conditions.

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The MRI appearances were variable, and no pathognomonic feature of PHL was identified, so that histology was required in all patients to establish the diagnosis. Patients who undergo THA after acetabular fracture have significantly worse functional outcome scores when compared with patients who undergo a primary THA for osteoarthritis. The velocity distribution function of ions of each ionization state, at several angles, in the plane of incidence, was investigated and was observed to depart significantly from the Maxwell-Boltzmann distribution function. A total of 63 actinomycetes were isolated from salt lake in Hami, of which 47 strains were halophilic actinomycetes. Both varicella and herpes zoster (HZ) can cause severe disease in certain age groups. Resistance zithromax 500 mg tabs exercise with older fallers: its impact on intermuscular adipose tissue.

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Prospective hospital-based study of all children referred to a neurodevelopment clinic between 2005 and 2009 with the diagnosis of either speech and language difficulties or behavioral difficulties. However, the mechanism regulating Hz recognition and IL-1beta maturation has not been identified. Reverse remodeling according to the increase in LVEF was developed independently from LV dyssynchrony improvement. Treatment of the differentiated HL60 cells with 3-methylcholanthrene, a ligand of AhR, induced the expression of the P450IA1 gene. In contrast, labelling with CTB-HRP revealed both myelinated and unmyelinated axons in the ventral horn, the ventrolateral white matter, and the ventral roots. These results suggest that an immune response of the sac may induce an excess secretion of endolymph in the initial stage and may further lead to irreversible dysfunction of the sac at a later stage. Striving for a healthy old age, however, is an infelicitous expression as for human subjects the ageing process cannot be ultimately postponed. Twenty-three of these ET 3 isolates had a distinctive antimicrobial resistance pattern also seen in isolates imported into the United States from Latin America and Southeast zithromax dosage adult Asia. NSAIDs have been shown to decrease the magnitude of the mucus-bicarbonate barrier, disrupt the epithelial cell layer, reduce the surface hydrophobicity of epithelial cells and to diminish mucosal blood flow. Expression of nm23-H1 predicts lymph node involvement in colorectal carcinoma.

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The purpose of this article is to review the typical risks associated with the transports of the patients with ABI out of the intensive care unit and to propose the strategies that can be used to minimize the risks of secondary brain injury. Coinfection resulted in increased levels of both pathogens and more severe Lyme arthritis compared with those in mice infected with B. The interface anchors the nematic phase in a planar way, i.e., the director aligns parallel to the interface. Despite their high cost, advanced therapies are likely to be cost-effective. Rapid tumor recurrence occurred after surgery, and he died 79 days after the operation.

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Despite the promise of kendomycinin in several therapeutic areas, its mode of action has yet to be identified. Prominence may be decreased by the use of microplates in the supraorbital, frontal, and naso-orbital-ethmoid locations. Alternatively, MS patients with poor QOL may be at greater risk of major depression. This is consistent with the global neuronal workspace hypothesis that associates conscious processing with surges of frontoparietal activity. On the basis of the histopathological and immunohistochemical features, large cell neuroendocrine carcinoma (LCNEC), T2aN0M0, stage IB was diagnosed. Cystadenocarcinoma of pancreas with staged pancreatoduodenectomy. Renal auto-transplantation represents a last resort solution in certain extreme situations when other simpler procedures are impossible and when preservation of the myambutol cost kidney is essential (solitary kidney or bilateral lesions).

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to evaluate if used of medication with antioxidants, antiplatelets, statins and modulators of inflammation reduces effectively the risk of presenting a cardiovascular disease (CVD). Omega-3 fatty acid supplementation has a beneficial effect on liver fat content and other cardiovascular risk factors in women with PCOS, including those with hepatic steatosis. The incidence of fractures in children under the age of 24 months--in relation to non-accidental injury. Molecular characterization of the Oncidium orchid HDR gene encoding 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase, the last step of the methylerythritol phosphate pathway. Conventional ceramic brackets show the highest degree of biocompatibility compared with polymeric and metal brackets and self-ligating brackets made from combinations of these materials. Selective stimulation of IgM synthesis in mouse B lymphocytes by pokeweed mitogen. Girls with dysfunctional eating with and without comorbid alcohol abuse reported greater sensitivity to punishment than alcohol abusing only girls. It has been hypothesized that dietary antioxidants could counteract the effects of heme iron.

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This investigation demonstrates that the loss of connective tissue attachment and progression of periodontal disease can be retarded by antagonists to specific host mediators such as IL-1 and TNF and may provide a potential treatment modality to combat the disease process. Mesh repair of ventral hernia is much superior to non-mesh suture repair in terms of recurrence and overall outcome. The reasons for the enhancement of RRS intensity were assumed as follows: resonance enhanced Rayleigh scattering effect, increase of the molecular volume, and hydrophobic effect. Host gene transcriptomes followed subset differentiation and viremia except in E-LTNPs wherein TCM, the main CD4 cell compartment, showed the highest activity with three specific signatures involving overexpression of T-cell receptor and costimulation signaling pathways, overexpression of the PRDM-1/Blimp-1 transcriptional repressor, and downmodulation of type-I IFN-related genes. On the basis of immunocytochemical characterization using monoclonal antibodies generated in our laboratory as well as several other glial-specific antibodies, we have established that the XR1 cells are derived from embryonic astroglia. Defining competencies for the practice of telepsychiatry through an assessment of resident learning needs. Ammonium was oxidized to nitrite by hypobromite and then the nitrite produced was determined spectrophotometrically, using sulfabenzamide and N levaquin an antibiotic -(1-naphthyl) ethylenediamine after solid phase extraction. Patients may have differing perceptions regarding routes to recovery based on preferences for professional services or spiritual resources.

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