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Metronour (Metronidazole)
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Metronour

Metronour is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis).

Other names for this medication:
Aldezol, Amotrex, Anegyn, Asuzol, Bemetrazole, Efloran, Geloderm, Klont, Lindoplus, Metazole, Metrajil, Metrodal, Metrofusin, Metrolotion, Metronidazols, Metronour, Metrosept, Monizole, Mtronidazole, Nidagel, Otrozol, Patryl, Protogyl, Riazole, Robaz, Rosasol, Rupezol, Tricozyl, Zyomet

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Also known as: Metronidazole

Description

Metronour (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Metronour is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.

Dosage

Metronour 250-mg tablets are round, blue, film coated, with SEARLE and 1831 debossed on one side and Metronour and 250 on the other side; bottles of 50, 100, and 2,500. Metronour 500-mg tablets are oblong, blue, film coated, with Metronour debossed on one side and 500 on the other side; bottles of 50, 100, and 500.

Overdose

In cases of overdose in adults, the clinical symptoms are usually limited to nausea, vomiting, ataxia and slight disorientation. In a preterm newborn, no clinical or biological sign of toxicity developed.

There is no specific treatment for Metronour overdose, Metronour infusion should be discontinued. Patients should be treated symptomatically.

Storage

Store below 77 degrees F (25 degrees C) and protect from light.

Side effects

The most common side effects associated with Metronour are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Metronidazole is mainly metabolised by hepatic oxidation. Substantial impairment of Metronidazole clearance may occur in the presence of advanced hepatic insufficiency. The risk/benefit ratio of using Metronidazole to treat trichomoniasis in such patients should be carefully considered. Plasma levels of Metronidazole should be closely monitored.

Cases of severe hepatotoxicity/acute hepatic failure, including cases with a fatal outcome with very rapid onset after treatment initiation in patients with Cockayne syndrome have been reported with products containing metronidazole for systemic use. In this population, metronidazole should therefore be used after careful benefit-risk assessment and only if no alternative treatment is available. Liver function tests must be performed just prior to the start of therapy, throughout and after end of treatment until liver function is within normal ranges, or until the baseline values are reached. If the liver function tests become markedly elevated during treatment, the drug should be discontinued.

Patients with Cockayne syndrome should be advised to immediately report any symptoms of potential liver injury to their physician and stop taking metronidazole.

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We conducted a retrospective review to identify factors that might predict for locoregional tumor control and its impact on overall survival. Recently, another gene (Cj0561c) strongly suppressed by the same repressor (CmeR) that regulates expression of CmeABC was identified in C. Seventy-three patients with MM, 27 with monoclonal gammopathy of undetermined significance, and 109 ethnically matched individuals as controls were included in the study. Patients will present with colorectal cancer despite having been invited to participate in the BCSP, with many having received a negative faecal occult blood test. Persistent NPs associated with plants enter the human food chain. The main measurements of resource utilization of services for treatment of respiratory-tract infections were the number of hospitalizations in the follow-up period of 24 weeks (0.41 rhDNase once daily, 0.56 placebo), the number of total days in hospital (4.9 rhDNase, 6.4 placebo), the number of total days of outpatient intravenous antibiotic therapy (2.9 rhDNase, 4.4 placebo), the number of total days of inpatient intravenous antibiotic therapy (4.8 rhDNase, 6.2 placebo), the number of total days of outpatient oral antibiotic therapy (23.5 rhDNase, 25.2 placebo) and the number of total days of inpatient oral antibiotic therapy (0.59 rhDNase, 0.55 placebo). Of these, 24 completed adjuvant external beam radiotherapy (EBRT), and 14 had intensity-modulated radiotherapy (IMRT). We develop a design equation to determine the thickness of the dielectric layer in a 3D plasmonic nanostructure that could create the maximum absorption at a given wavelength. A novel homogeneous immunoassay method is developed for sensitive monitoring of small molecular biotoxin by using a portable personal glucose meter (PGM) based on the target-responsive release of cargo (glucose) from a polystyrene microsphere-gated magnetic mesoporous nanocontainer. In the double lumen series, we found that oxygen saturation was less uniform and less stable than those in the single lumen series.

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An increased level of p21WAF1 expression was detected in stable transfectants although an exogenous reporter gene driven by p21WAF1 promoter exhibited lower activity in these cells suggesting that some post-transcriptional mechanism contributes to upregulation. Therapy efficacy, including adoptive T cell transfer, alkylating agents and immune checkpoint blockers, relies on immunity that receives its education from the gut microbiota. Gum chewing after eating caused only a transient elevation in plaque pH. Twenty-three edentulous adults with maxillary complete dentures who received three-implant-retained mandibular overdentures with ball or bar attachments by the same surgeon over a 1-year period were evaluated 3 years after overdenture loading. These cellular homologs of the viral oncogenes are termed proto-oncogenes. Increased serum GP88 (Progranulin) concentrations in rheumatoid arthritis. This shows that the potential consequences of giardiasis are more serious than previously known. The aim of this study was to compare the effects on intraocular pressure (IOP) of ropivacaine and bupivacaine in peribulbar block.

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Mapping the densities of malaria vectors within a single village. According to VALSG criteria, 138 patients had limited disease (LD), 13 had extensive disease (ED). In rats with experimental myocardial infarction and combined vascular pathology of brain and heart not all of the compounds mentioned acbove with GABA-ergic mechanism of action stimulate the cerebral blood flow. The EJCTS publication family is growing: the appointment of new editors for ICVTS and MMCTS. In the certain range of the parameters of the system the classical secular motion of the electronic ellipse reveals chaotic behavior. Equivalent numbers of both sexes were found to have mated, indicating that male squid routinely and indiscriminately mate with both males and females. Furthermore, INSIG2, LDLR, LRP1, and LRP10 were differentially regulated by GBE and lovastatin. Microalbuminuria is associated with long term poor glycemic control in adolescent insulin dependent diabetics. CAT-based administrations of the skin cancer risk scale could substantially reduce participant burden without compromising measurement precision.

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Activation of the MAPK/Akt/Nrf2-Egr1/HO-1-GCLc axis protects MG-63 osteosarcoma cells against 15d-PGJ2-mediated cell death. We have investigated the effect of the long-range Coulomb interaction on the one-particle excitation spectrum of n-type germanium, using tunneling spectroscopy on mechanically controllable break junctions. This article outlines a method and model in what happens if i drink alcohol while taking zithromax which DCs can effectively serve as public health advocates within their community. The aim of this study was to identify the role of KLF6 inhibition in estrogen receptor(alpha) (ERalpha)-elicited breast cancer development. The phenotypic and functional analysis of pbDCs in this novel therapeutic setting will provide a valuable tool for investigating mechanisms underlying treatment efficacy and for identifying predictors of treatment response. The aim of the study was to report our experience and to make an extensive literature research concerning SMM. However, the domain knowledge-based methods are hard to be applied due to the lack of direct functional annotation for miRNAs. Effect of spirometric maneuver on methacholine provocation test in asthmatic patients and normal subjects.

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Mild Concussion, but Not Moderate Traumatic Brain Injury, Is Associated with Long-Term Depression-Like Phenotype in Mice. The selective PDE III inhibitors offer a new modality for oral therapy of congestive heart failure. We have developed a rapidly acquired T1-weighted spin-echo pulse sequence that uses gradient echo-like parameters of TR 70 ms, TE 10 ms, NEX-1 (SE 70/10/1) with large pulse angles, and presaturation. The patients experiencing severe acute poisoning with acetic acid were divided into 2 groups with and without exotoxic shock to study platelet aggregation capacity and lymphocyte-platelet adhesion. The functional capacity of the adipose tissue varies among subjects explaining the incomplete overlapping among the metabolic syndrome and obesity. This review summarizes current mechanistic concepts of DILI in a 3-step model that limits its principle mechanisms to three main ways of initial injury, i.e.

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