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Metropast (Metronidazole)
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Metropast

Metropast is in a class of drugs called nitroimidazole antimicrobials. It works by stopping the growth of bacteria. This medicine will only help infections caused by bacteria and will not work for the common cold, flu, or other viral infections.

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Flagyl, Vantin, Sumycin, Ilosone, Myambutol, Omnicef

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Also known as: Metronidazole

Description

Metropast (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Metropast is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.

Dosage

In the Female. One-day treatment – two grams of Metropast, given either as a single dose or in two divided doses of one gram each, given in the same day. Seven-day course of treatment – 250 mg three times daily for seven consecutive days. There is some indication from controlled comparative studies that cure rates as determined by vaginal smears and signs and symptoms, may be higher after a seven-day course of treatment than after a one-day treatment regimen.

The dosage regimen should be individualized. Single-dose treatment can assure compliance, especially if administered under supervision, in those patients who cannot be relied on to continue the seven-day regimen. A seven-day course of treatment may minimize reinfection by protecting the patient long enough for the sexual contacts to obtain appropriate treatment. Further, some patients may tolerate one treatment regimen better than the other.

Pregnant patients should not be treated during the first trimester In pregnant patients for whom alternative treatment has been inadequate, the one-day course of therapy should not be used, as it results in higher serum levels which can reach the fetal circulation.

When repeat courses of the drug are required, it is recommended that an interval of four to six weeks elapse between courses and that the presence of the trichomonad be reconfirmed by appropriate laboratory measures. Total and differential leukocyte counts should be made before and after re-treatment.

Overdose

Single oral doses of Metropast, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Metropast has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Metropast overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.

Storage

Store Metropast at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Metropast out of the reach of children and away from pets.

Side effects

The most common side effects associated with Metropast are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Hypersensitivity. Metropast Tablets is contraindicated in patients with a prior history of hypersensitivity to metronidazole or other nitroimidazole derivatives. In patients with trichomoniasis, Metropast Tablets is contraindicated during the first trimester of pregnancy.

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Eye clinics at the University of Ottawa Eye Institute, Ottawa, Ontario, Canada. Recombinant tissue-type plasminogen activator is superior to streptokinase for local intra-arterial thrombolysis. In this paper, we attempt to describe/propose how to adopt vulnerability assessment through mathematical modeling of major biophysical social vulnerability factors to establish an independent, scientific, effieicnt and comprehensive provincial disaster medical system in Hainan. Correlations between the shoulder-specific and generic measures for baseline and 3-week change scores were lower than those among the shoulder-specific measures (range: 0.17-0.60). Evaluation of devices for removing attached Rhipicephalus sanguineus (Acari: Ixodidae). Hyperuricemia associates with hypertension, but it is uncertain whether this relationship is causal in nature. To develop this approach into a clinical setting it is important to be able to follow the fates of transplanted cells by noninvasive imaging. In vivo studies of glucose turnover have been complicated by the occurrence of theoretically impossible negative numbers for endogenous glucose production and it has only very recently been proposed that this could be due to radiochemical contamination of the tracers employed. Previous studies have demonstrated the expression of vimentin, BFSP1, and BFSP2 in the eye lens. In recent years, global changes are the major causes of frequent, widespread outbreaks of pests in mosaic landscapes, which have received substantial attention worldwide.

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A clear understanding of the impacts of nonideal computations is necessary to fully exploit the efficiency of analog circuits. In C2 enterovirus nucleic acid was demonstrated in 43 patients from CSF. Significant results from the initial study were verified using a second set of sera from 15 healthy patients, 15 breast cancer patients without clinical disease and 15 with metastatic disease, and a third set of 12 healthy and 18 patients with metastatic disease. Concentration of GSH was organ-dependent and was positively affected by estivation. Based on the assumption that homologous proteins may share a similar function, phylogenetic trees were reconstructed as an additional strategy to predict functions and evolutionary relationships of the honeybee desaturases and elongases. Annual report of the Australian Meningococcal Surveillance Programme, 2007--Amended. Other studies have shown that Polarization Sensitive Optical Coherence Tomography (PS-OCT) can be used to non-destructively measure the efficacy of fluoride in inhibiting the development of artificial caries lesions. WNT and bone morphogenetic protein (BMP vantin 200 mg bid ) signaling are known to stimulate hemogenesis from pluripotent embryonic stem (ES) cells. Agents that target components of the PI3K/AKT/mTOR pathway are under investigation for the treatment of diffuse large B cell lymphoma (DLBCL).

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