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Missilor (Metronidazole)
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Missilor

Missilor is in a class of drugs called nitroimidazole antimicrobials. It works by stopping the growth of bacteria. This medicine will only help infections caused by bacteria and will not work for the common cold, flu, or other viral infections.

Other names for this medication:
Aldezol, Aminidazole, Amodis, Amotein, Anabact, Deflamon, Flagenase, Flagystatine, Flegyl, Geloderm, Gynotran, Medamet, Metren, Metrocev, Metrocreme, Metrofusin, Metrogyl, Metrolotion, Metronidazolum, Metronide, Metrosa, Metrozole, Metsina, Monizole, Mtrocol, Negazole, Promuba, Protogyl, Rosaced, Rosazol, Rozacrme, Taremis, Torgyl, Trichazole, Trichopol, Tricofin, Trikozol, Trogyl, Vagilen, Zidoval, Zobacide, Zyomet

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Also known as: Metronidazole

Description

Missilor (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Missilor is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.

Dosage

When repeat courses of the drug are required, it is recommended that an interval of four to six weeks elapse between courses and that the pres- ence of the trichomonad be reconfirmed by appro- priate laboratory measures. Total and differential leukocyte counts should be made before and after re-treatment.

Overdose

Single oral doses of Missilor, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Missilor has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Missilor overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.

Storage

Store below 77 degrees F (25 degrees C) and protect from light.

Side effects

The most common side effects associated with Missilor are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Interaction with Alcohol. Use of oral metronidazole is associated with a disulfiram-like reaction to alcohol, including abdominal cramps, nausea, vomiting, headaches, and flushing. Discontinue consumption of alcohol or products containing propylene glycol during and for at least three days after therapy with metronidazole.

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