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Ospamox (Amoxicillin)
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Ospamox

Ospamox may be recommended to treat infections of the nose, ears, throat, urinary tract, or skin. It can also be used for pneumonia, tonsillitis, or bronchitis. Sometimes it’s given with other medicines to get rid of H. pylori, a species of bacteria that causes ulcers.

Other names for this medication:
Acimox, Alfamox, Aloxyn, Amoclen, Amoksicilin, Amoxi, Amoxicilina, Amoxicillin, Amoxicillinum, Amoxiline, Amoxisol, Amoxypen, Amurol, Bristamox, Cipmox, Clamoxyl, Flemoxon, Hidramox, Hydramox, Larotid, Moxicillin, Novamoxin, Ospamox, Penamox, Polymox, Raylina, Reloxyl, Robamox, Sintedix, Solciclina, Stacillin, Sumox, Tolodina, Utimox, Velamox, Wymox

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Ceftin, Avelox, Sumycin, Terramycin, Levaquin, Cefixime, Ilosone, Chloromycetin, Zithromax, Cleocin

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Also known as: Amoxicillin

Description

Ospamox is one of the best forms of antibiotic available today. It is used to treat infections caused by certain bacteria, including: infections of the ear, nose, and throat (pneumonia, bronchitis); infections of the genitourinary tract; infections of the skin and skin structure; infections of the lower respiratory tract; gonorrhea, acute uncomplicated (ano-genital and urethral infections) in male and females.

Ospamox is also used before some surgery or dental work to prevent infection. It is also used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers. Ospamox may also be used for other purposes not listed here.

Ospamox acts by inhibiting the synthesis of bacterial cell wall and stopping the growth of bacteria.

Ospamox is available in capsules.

Ospamox is usually taken every 8 hours (three times a day). It can be taken with or without food.

The chewable tablets should be crushed or chewed thoroughly before they are swallowed. The tablets and capsules should be swallowed whole and taken with a full glass of water.

Take Ospamox exactly as directed. Do not take more or less Ospamox or take it more often than prescribed by your doctor. Do not stop taking Ospamox without talking to your doctor. To clear up your infection completely, continue taking Ospamox for the full course of treatment even if you feel better in a few days. Stopping Ospamox too soon may cause bacteria to become resistant to antibiotics.

Dosage

Adults: 500 mg PO every 12 hours or 250 mg PO every 8 hours for mild/moderate infections and 875 mg PO every 12 hours or 500 mg PO every 8 hours for severe infections.

Infants 6 months and older, Children, and Adolescents: 80 to 90 mg/kg/day PO in divided doses every 12 hours is recommended by the American Academy of Pediatrics (AAP) as first-line therapy. Do not exceed 500 mg/dose if given every 8 hours or 875 mg/dose if given every 12 hours. AAP recommends a 10-day course for any child with severe disease and for all patients less than 2 years of age, regardless of severity. For children 2 to 5 years with mild to moderate disease, a 7-day course is acceptable. For children 6 years and older with mild to moderate disease, a 5- to 7-day course is acceptable. The FDA-approved dosage is 20 mg/kg/day PO in divided doses every 8 hours (Max: 250 mg/dose) or 25 mg/kg/day PO in divided doses every 12 hours (Max: 500 mg/dose) for mild to moderate infections and 40 mg/kg/day PO in divided doses every 8 hours (Max: 500 mg/dose) or 45 mg/kg/day PO in divided doses every 12 hours (Max: 875 mg/dose) for severe infections.

Infants 4 to 5 months: 80 to 90 mg/kg/day PO given in divided doses every 12 hours for 10 days was recommended by experts as first-line therapy in previous guidelines ; however, this age group is not addressed in the most current guidelines by the American Academy of Pediatrics (AAP). The FDA-approved dosage is 20 mg/kg/day PO in divided doses every 8 hours or 25 mg/kg/day PO in divided doses every 12 hours for mild to moderate infections and 40 mg/kg/day PO in divided doses every 8 hours or 45 mg/kg/day PO in divided doses every 12 hours for severe infections.

Infants 3 months and younger: 30 mg/kg/day PO given in divided doses every 12 hours is the general FDA-approved dosing. Young infants are less capable of responding to infection, and the clinical manifestations of infection can be subtle. Because of the increased risk for complications of an undiagnosed systemic infection, every young infant presenting with a fever should be carefully evaluated.

Overdose

In case of overdosage, discontinue medication, treat symptomatically, and institute supportive measures as required. If the overdosage is very recent and there is no contraindication, an attempt at emesis or other means of removal of drug from the stomach may be performed. A prospective study of 51 pediatric patients at a poison-control center suggested that overdosages of less than 250 mg/kg of Ospamox are not associated with significant clinical symptoms and do not require gastric emptying.

Interstitial nephritis resulting in oliguric renal failure has been reported in a small number of patients after overdosage with Ospamox.

Crystalluria, in some cases leading to renal failure, has also been reported after Ospamox overdosage in adult and pediatric patients. In case of overdosage, adequate fluid intake and diuresis should be maintained to reduce the risk of Ospamox crystalluria.

Renal impairment appears to be reversible with cessation of drug administration. High blood levels may occur more readily in patients with impaired renal function because of decreased renal clearance of Ospamox. Ospamox may be removed from circulation by hemodialysis.

Storage

Generic: store at controlled room temperature (between 68 and 77 degrees F)

Amoxil: store at controlled room temperature (between 68 and 77 degrees F)

Moxatag: store at 77 degrees F; excursions permitted to 59-86 degrees F

Moxilin: store at controlled room temperature (between 68 and 77 degrees F)

Sumox: store at controlled room temperature (between 68 and 77 degrees F)

Trimox: store at controlled room temperature (between 68 and 77 degrees F)

Side effects

The most common side effects associated with Ospamox are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Children, infants, neonates, premature neonates.

Ospamox has been used to treat infections in infants (3 months of age), including neonates and premature neonates. However, dosages must be modified for these age groups compared to infants (3 months of age) because of incompletely developed renal function. Safety and effectiveness of Moxatag extended-release tablets has not been established in neonates, infants, or children (12 years of age).

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Intravitreal bevacizumab for prevention of early postvitrectomy hemorrhage in diabetic patients: a randomized clinical trial. Long-term effects of multielectrode renal denervation on cardiac adaptations in resistant hypertensive patients with left ventricular hypertrophy. We show that E7-specific antibodies and CD4 T helper responses can be obtained by vaccinating E7 transgenic mice, although a CTL response was not detected. In an effort to further improve the overall accumulation of arsenic, cysteine desulfhydrase, an aminotransferase that converts cysteine into hydrogen sulfide under aerobic condition, was co-expressed in order to promote the formation of larger AsS complexes. Three types of insecticides including organophosphorus, chlorinated and fluorine compounds were analyzed by gas chromatography/mass spectrometry in order to establish a sensitive and selective method.

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Cloning of a thermostable alpha-amylase gene from Thermomonospora curvata and its expression in Streptomyces lividans. Abnormalities of surfactant action in acute respiratory distress syndrome (ARDS) result in decreased lung compliance and significant hypoxemia. The patient survived the suicide attempt with only supportive care, despite the ingestion of 392 mg/kg and a peak serum level of 100.8 micrograms/mL. Emerging treatment options for relapsed and refractory multiple myeloma. An electron microscopic study of neuronal development in organotypic cultures of the anlage of the cerebral cortex from a human embryo. Randomized tree construction algorithm to explore energy landscapes. Effects of sodium tanshinone II A sulphonate on hypoxic pulmonary hypertension in rats in vivo and on Kv2.1 expression in pulmonary artery smooth muscle cells in vitro. Electrocardiographic changes and rhythm problems in the diabetic. A direct path to convert thin film to nanowires can build a bridge between these two and therefore facilitate the large-scale applications of nanowires.

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Enantioselective determination of thiamylal in human serum by high-performance liquid chromatography. Across QTL pairs, there are significantly positive and negative interactions for every trait. Logistic regression models were created to explore associations between clinicodemographic factors and surgical complications. Effects of tacrine derivatives on the behaviour of laboratory rats. Fear of falling is prevalent among robust community-dwelling older people regardless of their fall history. However, in the surface layer, mucous cells were significantly larger in number than in the apical epithelium. SagB Glucosaminidase Is a Determinant of Staphylococcus aureus Glycan Chain Length, Antibiotic Susceptibility, and Protein Secretion. The accumulation of collagen was inhibited, but an increase in CCl4-toxicity with high mortality was observed. Ten unstable zygomatic bone fractures were treated with osteosynthesis plates and screws made of bioabsorbable poly(l-lactide) (PLLA). Peak assignments are based on DFT-calculated Mulliken spin densities, which lead noroxin drug to the surprising result that the largest paramagnetic shift affecting a proton NMR resonance in 2 originates from intermolecular interactions.

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