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Pedrox (Roxithromycin)
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Pedrox

Pedrox is indicated for the treatment of the following mild to moderately severe infections in children caused by or likely to be caused by susceptible micro-organisms: acute pharyngitis, acute tonsillitis and impetigo.

Other names for this medication:
Acevor, Aristomycin, Asmetic, Azuril, Bazuctril, Biaxsig, Bicofen, Biostatik, Cadithro, Claramid, Crolix, Delos, Dorolid, Elrox, Erybros, Floxid, Infectoroxit, Ladlid, Macrosil, Nirox, Overal, Pedilid, Pedrox, Ramivan, Remora, Renicin, Ritosin, Rokithrid, Roksolit, Rolexit, Rolicyn, Romac, Rossitrol, Rotramin, Roxacine, Roxithromycin, Roxithromycine, Roxithromycinum

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Also known as: Roxithromycin

Description

Each Pedrox tablet contains either 150mg or 300mg of the active ingredient roxithromycin. Each tablet also contains: hydroxypropylcellulose, poloxamer, povidone, colloidal anhydrous silica, magnesium stearate (470), purified talc (553), maize starch, hypromellose, anhydrous glucose, titanium dioxide (171), propylene glycol (1520). Pedrox does not contain gluten, sucrose, lactose, tartrazine or any other azo dyes.

Dosage

Take Generic Pedrox by mouth with food. If you have trouble swallowing the tablet whole, it may be crushed or chewed with a little water. Swallow Generic Pedrox tablets whole with a glass of water. Generic Pedrox should be taken at least 15 minutes before food or on an empty stomach (i.e. more than 3 hours after a meal). Generic Pedrox works best if you take it on an empty stomach. For treating bacterial infections, Generic Pedrox is usually taken for 5 to 10 days. If you want to achieve most effective results do not stop taking Generic Pedrox suddenly.

Overdose

Immediately telephone your doctor or pharmacist. Do this even if there are no signs of discomfort or poisoning.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Do not store in the bathroom. Keep in a tight, light-resistant container. Keep out of the reach of children.

Side effects

The most common side effects associated with Pedrox are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

The safety of roxithromycin has not been demonstrated in patients with impaired hepatic or renal function. Caution should be exercised if roxithromycin is administered to patients with impaired hepatic or renal function. If administered to patients with severe impaired hepatic function (eg. hepatic cirrhosis with jaundice and/or ascites), consideration should be given to reducing the daily dosage to half the usual dosage.

Prolonged or repeated use of antibiotics including roxithromycin may result in superinfection by resistant organisms. In the event of superinfection, roxithromycin should be discontinued and appropriate therapy instituted.

When indicated, incision, drainage or other appropriate surgical procedures should be performed in conjunction with antibiotic therapy.

Antibiotic associated pseudomembranous colitis has been reported with many antibiotics. A toxin produced by Clostridium difficile appears to be the primary cause. The severity of the colitis may range from mild to life threatening. It is important to consider this diagnosis in patients who develop diarrhoea or colitis in association with antibiotic use (this may occur up to several weeks after cessation of antibiotic therapy). Mild cases usually respond to drug discontinuation alone. However, in moderate to severe cases, appropriate therapy with a suitable oral antibacterial agent effective against Clostridium difficile should be considered. Fluids, electrolytes and protein replacement therapy should be provided when indicated.

Roxithromycin, like erythromycin, has been shown in vitro to elicit a concentration - dependent lengthening in cardiac action potential duration. Such an effect is manifested only at supra – therapeutic concentrations. Accordingly, the recommended doses should not be exceeded. In certain conditions macrolides, including roxithromycin, have the potential to prolong the QT interval. Therefore roxithromycin should be used with caution in patients with congenital prolongation of the QT interval, with ongoing proarrhythmic conditions (ie uncorrected hypokalemia or hypomagnesaemia, clinically significant bradycardia), and in patients receiving Class IA and III antiarrhythmic agents.

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Data were collected using self-report measures of attitudes towards breakfast, parental and peer descriptive norms, parental, peer and teacher related injunctive norms, self-efficacy for eating breakfast and self-reported habitual breakfast skipping. Rheological significance of tandem lesions of the coronary artery. We used spectrophotometric assays with 3 specific substrates (L-tyrosine for tyrosinase, L-DOPA for catecholase, and PPD for laccase) and diethylthiocarbarmate (DETC) as specific PO inhibitor to characterize PO activity in the hemolymph of uninfected snails from two Biomphalaria species, and to determine the impact of the parasite Schistosoma mansoni on the PO activity of its B. Living-donor pancreas transplants (LDPs) were introduced at Chiba-East National Hospital in 2004, and 12 LDPs have been performed at this institution to date. Evidence for osteocyte regulation of bone homeostasis through RANKL expression. To explore the concept of sustainability in nursing using social media as a vehicle for discussion on the topic. The purpose of this article is to define the concept of surgical skill and to discuss how it can be measured in the context of validating VR surgical simulators.

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Body weight changes and clinical outcome in adults on antiretroviral therapy in countries with limited resources. When osteocytes are subjected to FFSS followed by a brief rest and reapplication of FFSS, it led to further increase in opening of Cx43 hemichannels. Sardinia, insular Italy, is among the regions at highest risk for MS worldwide. Frozen section investigation of the sentinel node in malignant melanoma and breast cancer. With the identification of circulating molecular forms of BNP, new insights regarding the biology of the BNP system are emerging that may improve the diagnostic and prognostic value of BNP. Interference of alpha-alkyl-substituted pirinixic acid derivatives with neutrophil functions and signalling pathways. Amyotrophic lateral sclerosis (ALS) is one of the most common neurodegenerative disorders, but no definite mechanism has been defined on the loss of motor neurons in ALS and currently no therapy can block its progression.

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