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Polymox (Amoxicillin)
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Polymox

Polymox may be recommended to treat infections of the nose, ears, throat, urinary tract, or skin. It can also be used for pneumonia, tonsillitis, or bronchitis. Sometimes it’s given with other medicines to get rid of H. pylori, a species of bacteria that causes ulcers.

Other names for this medication:
Alfamox, Almodan, Aloxyn, Amoclen, Amoksicilin, Amoram, Amoxi, Amoxicilina, Amoxicillinum, Amoxivet, Amoxypen, Amurol, Bimoxan, Bristamox, Cipmox, Clamoxyl, Flemoxin, Flemoxon, Galenamox, Gimalxina, Hydramox, Lupimox, Ospamox, Polymox, Raylina, Servamox, Sintedix, Solciclina, Stacillin, Sumox, Tolodina, Utimox, Velamox, Wymox, Zimox

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Myambutol, Cleocin, Chloromycetin, Levaquin, Suprax, Rulide, Zithromax, Ilosone, Terramycin, Ceftin

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Also known as: Amoxicillin

Description

Polymox is one of the best forms of antibiotic available today. It is used to treat infections caused by certain bacteria, including: infections of the ear, nose, and throat (pneumonia, bronchitis); infections of the genitourinary tract; infections of the skin and skin structure; infections of the lower respiratory tract; gonorrhea, acute uncomplicated (ano-genital and urethral infections) in male and females.

Polymox is also used before some surgery or dental work to prevent infection. It is also used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers. Polymox may also be used for other purposes not listed here.

Polymox acts by inhibiting the synthesis of bacterial cell wall and stopping the growth of bacteria.

Polymox is available in capsules.

Polymox is usually taken every 8 hours (three times a day). It can be taken with or without food.

The chewable tablets should be crushed or chewed thoroughly before they are swallowed. The tablets and capsules should be swallowed whole and taken with a full glass of water.

Take Polymox exactly as directed. Do not take more or less Polymox or take it more often than prescribed by your doctor. Do not stop taking Polymox without talking to your doctor. To clear up your infection completely, continue taking Polymox for the full course of treatment even if you feel better in a few days. Stopping Polymox too soon may cause bacteria to become resistant to antibiotics.

Dosage

Polymox may be taken every 8 hours or every 12 hours, depending on the strength of the product prescribed.

Patients should be counseled that antibacterial drugs, including Polymox, should only be used to treat bacterial infections. They do not treat viral infections (e.g., the common cold). When Polymox is prescribed to treat a bacterial infection, patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed. Skipping doses or not completing the full course of therapy may: (1) decrease the effectiveness of the immediate treatment, and (2) increase the likelihood that bacteria will develop resistance and will not be treatable by Polymox or other antibacterial drugs in the future.

Diarrhea is a common problem caused by antibiotics which usually ends when the antibiotic is discontinued. Sometimes after starting treatment with antibiotics, patients can develop watery and bloody stools (with or without stomach cramps and fever) even as late as 2 or more months after having taken the last dose of the antibiotic. If this occurs, patients should contact their physician as soon as possible.

Overdose

In case of overdosage, discontinue medication, treat symptomatically, and institute supportive measures as required. If the overdosage is very recent and there is no contraindication, an attempt at emesis or other means of removal of drug from the stomach may be performed. A prospective study of 51 pediatric patients at a poison-control center suggested that overdosages of less than 250 mg/kg of Polymox are not associated with significant clinical symptoms and do not require gastric emptying.

Interstitial nephritis resulting in oliguric renal failure has been reported in a small number of patients after overdosage with Polymox.

Crystalluria, in some cases leading to renal failure, has also been reported after Polymox overdosage in adult and pediatric patients. In case of overdosage, adequate fluid intake and diuresis should be maintained to reduce the risk of Polymox crystalluria.

Renal impairment appears to be reversible with cessation of drug administration. High blood levels may occur more readily in patients with impaired renal function because of decreased renal clearance of Polymox. Polymox may be removed from circulation by hemodialysis.

Storage

Generic: store at controlled room temperature (between 68 and 77 degrees F)

Amoxil: store at controlled room temperature (between 68 and 77 degrees F)

Moxatag: store at 77 degrees F; excursions permitted to 59-86 degrees F

Moxilin: store at controlled room temperature (between 68 and 77 degrees F)

Sumox: store at controlled room temperature (between 68 and 77 degrees F)

Trimox: store at controlled room temperature (between 68 and 77 degrees F)

Side effects

The most common side effects associated with Polymox are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Geriatric. Based on manufacturer data, geriatric patients (above 65 years) do not respond differently to Polymox treatment than younger patients. However, a greater sensitivity to Polymox in elderly patients could not be ruled out. Polymox is known to be substantially excreted via the kidney. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection for elderly patients; renal function monitoring may be useful. The federal Omnibus Budget Reconciliation Act (OBRA) regulates medication use in residents of long-term care facilities. According to OBRA, use of antibiotics should be limited to confirmed or suspected bacterial infections. Antibiotics are non-selective and may result in the eradication of beneficial microorganisms while promoting the emergence of undesired ones, causing secondary infections such as oral thrush, colitis, or vaginitis. Any antibiotic may cause diarrhea, nausea, vomiting, anorexia, and hypersensitivity reactions.

Pregnancy. Polymox is classified in FDA pregnancy risk category B. Animal data reveal no teratogenic effects, however, there are no adequate and well-controlled studies in pregnant women. While Polymox should be used with caution in pregnancy, penicillins are usually considered safe during pregnancy when clearly needed.

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There will be no difference in reinjury rate between low-grade (grades I and II) and high-grade (IIIA and IIIB) acute lateral ankle sprains. Energetics of coiled coil folding cipro antibiotics : the nature of the transition states. Coexistence of intra- and extra-uterine pregnancy: a clinical case. It was noteworthy that there were no significant relationships between the falx cerebri and the tentorium cerebelli in such element contents as calcium, phosphorus, magnesium, sulfur, iron, and zinc. Effects of natural cartilaginous extracellular matrix on chondrogenic potential for cartilage cell transplantation.

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Determination of fast structural changes of biomolecules is usually performed on crystalline samples in a time-resolved pump-probe experiment. Bacterial tracheitis is a relatively rare cause of respiratory distress in children and is associated with a high morbidity and mortality rate. Neurons in the cockroach nervous system reacting with antisera to the neuropeptide leucokinin I. The present review will illustrate this interaction by selecting examples from innate immunity and adaptive immunity, and their direct impact on each other. Using Brownian dynamics, we determine the dependence of the band width on the strength of the particle interactions and on the levaquin drug class intensity and periodicity of the field. Sequence analysis of NRT1.1 in the mutant revealed a nonsense mutation that truncated the NRT1.1 protein at amino acid 301.

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