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Riazole (Metronidazole)
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Riazole

Riazole is in a class of drugs called nitroimidazole antimicrobials. It works by stopping the growth of bacteria. This medicine will only help infections caused by bacteria and will not work for the common cold, flu, or other viral infections.

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Aldezol, Amobin, Amotein, Amotrex, Anerozol, Arilin, Colpofilin, Farnat, Flagystatin, Mecozol, Menilet, Metrocreme, Metrodal, Metrogyl, Metrolyl, Metropast, Metsina, Minegyl, Nipazol, Pharmaflex, Protogyl, Rosiced, Rozacrme, Rozagel, Trichomonacid, Tricodazol, Vertisal, Zobacide

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Cleocin, Vantin, Avelox, Chloromycetin, Floxin, Omnicef, Biaxin, Suprax, Amoxil

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Also known as: Metronidazole

Description

Riazole (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Riazole is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.

Dosage

In elderly patients, the pharmacokinetics of metro- nidazole may be altered, and, therefore, monitor- ing of serum levels may be necessary to adjust the metronidazole dosage accordingly.

Overdose

Single oral doses of Riazole, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Riazole has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Riazole overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.

Storage

Store below 77 degrees F (25 degrees C) and protect from light.

Side effects

The most common side effects associated with Riazole are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Hypersensitivity. Riazole Tablets is contraindicated in patients with a prior history of hypersensitivity to metronidazole or other nitroimidazole derivatives. In patients with trichomoniasis, Riazole Tablets is contraindicated during the first trimester of pregnancy.

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