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Rokithrid (Roxithromycin)

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Rokithrid is indicated for the treatment of the following types of mild to moderately severe infections in adults caused by or likely to be caused by susceptible microorganisms. Upper respiratory tract infections: acute pharyngitis, tonsillitis, sinusitis.

Other names for this medication:
Acevor, Aristomycin, Azuril, Biaxsig, Bicofen, Biostatik, Claramid, Delos, Dorolid, Erybros, Floxid, Infectoroxit, Macrosil, Monobac, Nirox, Odonticina, Overal, Pedilid, Renicin, Ritosin, Rokilide, Rokithrid, Romac, Romyk, Rotramin, Roxacine, Roxithromycin, Roxithromycine, Roxitromicina

Similar Products:
Cleocin, Keflex, Ceftin, Amoxil, Terramycin, Zithromax, Cefixime, Floxin, Omnicef, Chloromycetin

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Also known as: Roxithromycin


Each Rokithrid tablet contains either 150mg or 300mg of the active ingredient roxithromycin. Each tablet also contains: hydroxypropylcellulose, poloxamer, povidone, colloidal anhydrous silica, magnesium stearate (470), purified talc (553), maize starch, hypromellose, anhydrous glucose, titanium dioxide (171), propylene glycol (1520). Rokithrid does not contain gluten, sucrose, lactose, tartrazine or any other azo dyes.


Rokithrid is typically prescribed for a period of 7 to 14 days and patients should take the medication for as long as it has been prescribed to prevent the infection from returning even if they become asymptomatic. Patients should not however, take doses larger than has been prescribed as this can result in an overdose. Overdosing requires immediate medical intervention and may present with symptoms which include abdominal pain, nausea, diarrhea, vomiting, and a general and prolonged feeling of illness.


Immediately telephone your doctor or pharmacist. Do this even if there are no signs of discomfort or poisoning.


Keep your tablets in the blister pack until it is time to take them. If you take the tablets out of the blister pack they may not keep well.

Keep the medicine in a cool, dry place where the temperature stays below 25 degrees C.

Do not store it or any other medicine in the bathroom, near a sink or on windowsill.

Do not leave it in the car. Heat and damp can destroy some medicines.

Keep it where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

Side effects

The most common side effects associated with Rokithrid are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


The safety of roxithromycin has not been demonstrated in patients with impaired hepatic or renal function. Caution should be exercised if roxithromycin is administered to patients with impaired hepatic or renal function. If administered to patients with severe impaired hepatic function (eg. hepatic cirrhosis with jaundice and/or ascites), consideration should be given to reducing the daily dosage to half the usual dosage.

Prolonged or repeated use of antibiotics including roxithromycin may result in superinfection by resistant organisms. In the event of superinfection, roxithromycin should be discontinued and appropriate therapy instituted.

When indicated, incision, drainage or other appropriate surgical procedures should be performed in conjunction with antibiotic therapy.

Antibiotic associated pseudomembranous colitis has been reported with many antibiotics. A toxin produced by Clostridium difficile appears to be the primary cause. The severity of the colitis may range from mild to life threatening. It is important to consider this diagnosis in patients who develop diarrhoea or colitis in association with antibiotic use (this may occur up to several weeks after cessation of antibiotic therapy). Mild cases usually respond to drug discontinuation alone. However, in moderate to severe cases, appropriate therapy with a suitable oral antibacterial agent effective against Clostridium difficile should be considered. Fluids, electrolytes and protein replacement therapy should be provided when indicated.

Roxithromycin, like erythromycin, has been shown in vitro to elicit a concentration - dependent lengthening in cardiac action potential duration. Such an effect is manifested only at supra – therapeutic concentrations. Accordingly, the recommended doses should not be exceeded. In certain conditions macrolides, including roxithromycin, have the potential to prolong the QT interval. Therefore roxithromycin should be used with caution in patients with congenital prolongation of the QT interval, with ongoing proarrhythmic conditions (ie uncorrected hypokalemia or hypomagnesaemia, clinically significant bradycardia), and in patients receiving Class IA and III antiarrhythmic agents.

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None of the deleted forms was capable of transformation of fibroblasts. Patterns of genetic diversity in population complexes of Pacific chum salmon Oncorhynchus keta Walbaum, from Asia and Northern America, inferred from allozyme polymorphism data. To control for RNAs that nonspecifically co-purify with the RNA-binding protein, transgenic plants are generated with a mutated version of the RNA-binding protein that is not capable of binding to its target RNAs. The delivery of oral rabies vaccines to dogs: an African perspective. Anomalous muscle bands in right ventricular cavity were detected in 16 patients. Cost effectiveness was pound36 600, pound13 600, and pound4000 per life year gained at five years and pound5300, pound1900, and pound100 per life year gained at 20 years (lifetime treatment) in low, medium, and high risk groups, respectively. The clinical, endoscopic, radiological, and pathological features of glutaraldehyde-induced colitis may mimic those of ischemic colitis. L-Arginine regulates the expression of the T-cell receptor zeta chain (CD3zeta) in Jurkat cells. Surgery on intracranial aneurysms under simultaneous microscopic and endoscopic monitoring. We demonstrate experimentally that in wavelength-scale cavities of a fixed shape, the neighboring modes can have dramatically different emission directionality.

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Evaluation of the FRAX model for hip fracture predictions in the population-based Kuopio Osteoporosis Risk Factor and Prevention Study (OSTPRE). Down-regulation of lipoprotein lipase increases glucose uptake in L6 muscle cells. Strong in situ hybridization signals were detected in EBNA2-transfected cells with the antisense probe but not with the sense probe of this mRNA. Differences between target refractions calculated using 5 IOL formulas and 2 A-constants and achieved refractions were also compared. Progress toward advanced understanding of metabotropic glutamate receptors: structure, signaling and therapeutic indications. In each subject, the contralateral mucosa served as a control to the implant sites. In addition, inflammatory proteins in the urine and serum play important roles in the pathogenesis of bladder pain syndrome/interstitial cystitis. The order of neurogenesis was found to be highly conserved across a wide range of mammals and to correlate with the relative enlargement of structures as brain size increases, with disproportionately large growth occurring in late-generated structures. A rationale for the symmetries by base substitutions of degeneracy in the genetic code.

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Management of condylar fractures in patients with cervical spine injury: report of cases. A kinetic characterisation showed a non-competitive mechanism against glutamate and an uncompetitive mechanism against ATP. Over-expression of cyclin D1 in chronic B-cell malignancies with abnormality of chromosome 11q13. The impairment of the male patients is associated with an unfavorable prognosis. Understanding the actual corneal optical contour resulting from PRK may aid in improving both laser techniques and optical results in the future. In both the routine and intensive educational approaches, most adolescents learned the name, dose, target symptoms, and benign side effects of their medication, but not the more serious side effects or alternatives to the treatment. Although enteric ganglia share neural crest lineage with other sites of congenital neuroblastoma, this is the first report of a primary intestinal ganglioneuroblastoma in a fetus or child. Albuminuria was significantly lower at 2, 4, and 6 months of age.

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Accuracy of neurologic examination and history in detecting evidence of MRI-diagnosed cerebral infarctions in children with sickle cell hemoglobinopathy. Both the UT and LT groups demonstrated significant improvement in clinical and radiographic outcomes. Growth factors can enhance lymphocyte survival without committing the cell to undergo cell division. Together, these effects of SAP regulate key aspects of inflammation and set a threshold for immune cell activation. Digital signal transmission with cascaded heterogeneous chaotic systems.

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The angiotensin II (Ang II) type 1 (AT(1)) receptor is expressed in bone marrow (BM) cells, whereas it remains poorly defined how Ang II regulates differentiation/proliferation of monocyte-lineage cells to exert proatherogenic actions. The presence and size of the gestational sac, presence of a yolk sac, and identification of embryonic heart activity were correlated zithromax antibiotic in spanish with the level of HCG. This paper reviews recent researches about the source, determination, exposure level, toxicological effects and transformation pathways of OH-PBDEs. X-ray microanalysis of calcium containing organelles in resin embedded tissue. Effect of ethinyl-oestradiol on some neurohypophysial active compounds in the rat. Apoptosis, or programmed cell death, seems to play a role in the physiology of shock. Patients achieving response received maintenance with rituximab 375 mg/m(2) every 3 months for 2 years.

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MicroRNA expression profile of dexamethasone-induced human bone marrow-derived mesenchymal stem cells during osteogenic differentiation. This powerful emotion has been neglected by both clinicians and researchers. The use of a simple syringe can prevent bothersome condensation on the scope lens during laparoscopic surgery. An exercise-induced transient renal dysfunction is proposed as a hypothetic explanation for these observations that rely on parallel investigations of proteinuria in the same samples. Rapid and adaptive responses to stresses are therefore crucial for cell survival. An actual severe problem in agriculture consists of an expressive increase of economical losses caused by fungi how long after last dose of flagyl can i drink and resistant bacteria toward antibiotics.

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Diffusion weighted MR imaging can be performed during a standard cranial MR examination and add useful clinical information in several brain disorders besides acute ischemic stroke. Sequential treatment of the label with acid and a strong base, one of which contains a peroxide, initiates light emission as a rapid flash lasting 1--2 s. Receptor-ligand interactions result in forward and reverse signalling from the receptor and ligand respectively. This increase risk could be due to either gonadotropins used for ovarian stimulation or in vitro culture conditions or multiple pregnancy or combinations of all the factors. Investigation into the impact of maternal depression and offspring behavior has relied on correlative studies in humans. To describe the epidemiology, clinical signs, and treatment practices in dogs with Yersinia pestis infection in New Mexico. Genistein sensitizes human hepatocellular carcinoma cells to TRAIL-mediated apoptosis by enhancing Bid cleavage. The decapod Grapsus grapsus is commonly found on oceanic islands of the Pacific and Atlantic coasts of the Americas. Cooling augments contractile response to 5-hydroxytryptamine via an endothelium-dependent mechanism.

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Because of the low incidence of penile carcinoma (PC), the value of p16(ink4a), p53, and human papilloma virus (HPV) infection status in clinical practice remains unclear. Is the Grading of Liver Injuries a Useful Clinical Tool in the Initial Management of Blunt Trauma Patients?. For the choice of place of study, affordability, social ties as well as an educational system following the achievement principle are decisive factors. In this systematic review, the authors summarize the current evidence in the literature regarding diagnosis, treatment, and long-term outcomes in neonates with tongue-based airway obstruction (TBAO) and assess the level of evidence of included studies. Viscoelastic coagulation evaluation could be used in a neonatal intensive care unit setting to further characterize coagulopathy, and identify foals at higher risk for poor outcome.

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Cell cycle control at the first restriction point and its effect on tissue growth. We report clinical experiences with a can i use tetracycline antibiotic while breastfeeding simple, rapid method of detecting varicose veins using indocyanine green (ICG) fluorescence video venography. In vitro corrosion of pure magnesium and AZ91 alloy-the influence of thin electrolyte layer thickness. Overexpression of the Csk homologous kinase (Chk tyrosine kinase) induces multinucleation: a possible role for chromosome-associated Chk in chromosome dynamics. Understanding the mechanisms by which cells sense and respond to these directional cues warrants a quantitative assessment of macroscopic cellular response to the surface gradients, supported by predictive theoretical models. Cardiovascular effects of cocaine in humans: laboratory studies. Multiple cytotoxic effector cells are induced by infection with the human immunodeficiency virus.

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We analyzed the orthologous human EB (14q32.33), known to be associated with translocations in many cancers including multiple myelomas and plasma cell leukemias, and found a conserved distribution of similar repetitive elements. We present a case of left-sided sciatic hernia with incarcerated small bowel as its contents. Bacteria and fungi naturally coexist in various environments including forest ecosystems. The uptake of 59Fe by erythroid cells was significantly inhibited at doses of 20, 25, and 30 mg/kg. In contrast, yeast BER-defective cells accumulate endogenous damage preferentially on the CAN1 transcribed strand. The multidrug resistance 1 gene (MDR1) C3435T polymorphism has been demonstrated to influence the P-glycoprotein (P-gp) activity level which is related to inflammation and carcinogenesis. Moreover, it shows that concentrations of metals such as cadmium, chromium, lead and nickel in hair may be used as a biomarker of exposure. Male hamsters discriminate estrous state from vaginal secretions and individuals from flank marks.

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This study aims to analyze the experiences of Dutch bereaved parents and general practitioners (GPs) with palliative care of AYAs (18-35 years) in the terminal stage. In this cleocin 500 mg system, a single guide RNA (sgRNA) directs the endonuclease Cas9 to a targeted DNA sequence for site-specific manipulation. Bouncing back from failure: the interactive impact of perceived controllability and stability on self-efficacy beliefs and future task performance. Wild-type and ICAM-1 knockout mice were assessed for resistance to ocular HSV-1 infection in the presence of naked DNA plasmid vector or plasmid DNA encoding interferon-alpha1 topically applied to the cornea of the mice. Whilst RHD increased the risk of IE it was not restricted to Indigenous Australians.

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Both liquids are strongly dispersive and used as a background medium in the imaging examples. From higher-level ab initio calculations, the potential energy surface of the dimer indicates the presence of a region with two local minima within 3.42 kcal/mol difference in energy. The outcomes of patients with CKD and acute coronary syndromes (ACS) have not been well studied. Ifosfamide-containing therapy with cisplatin plus either etoposide (VIP) or vinblastine (VeIP) can cure of patients with relapsed germ cell tumors (GCTs), but results in substantial myelotoxicity. Myocardial clearance kinetics of technetium-99m-teboroxime following dipyridamole: differentiation of stenosis severity in canine myocardium.

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