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Simpli (Azithromycin)

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Simpli is in a group of drugs called macrolide antibiotics. Simpli fights bacteria in the body. Simpli is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections, ear infections, and sexually transmitted diseases. Simpli may also be used for purposes other than those listed in this medication guide.

Other names for this medication:
Azenil, Azimakrol, Azimycin, Azirox, Azithral, Azithromycin, Azromax, Aztrin, Bactexina, Bactrazol, Cinalid, Disithrom, Doyle, Iramicina, Koptin, Macromax, Misultina, Ordipha, Penalox, Ricilina, Rozith, Sitrox, Trozocina, Unizitro, Vectocilina, Zetamax, Zistic, Zithrin, Zithrocin, Zithromac, Zithromycin, Zitrocin, Zitrolid, Zycin

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Also known as: Azithromycin


Simpli is used to treat bacterial infections in many different parts of the body. It is also used to prevent Mycobacterium avium complex (MAC) disease in patients infected with the human immunodeficiency virus (HIV).

Simpli belongs to the class of drugs known as macrolide antibiotics. It works by killing bacteria or preventing their growth. However, Simpli will not work for colds, flu, or other virus infections. Simpli injection may be used for other problems as determined by your doctor.

Simpli is available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, Simpli is used in certain patients with the following medical condition: Trachoma (treatment).


Dosage of Simpli is setted individually according to nosology, disease severity and sensitivity of the pathogen. Dosage for adults for oral administration is 0.25-1 g 1 time/day; for children - 5-10 mg/kg 1 time/day. The duration of administration is 2-5 days.


If you overdose Simpli and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Simpli overdosage: discomfort feeling in stomach, diarrhea, retching, nausea.


Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets. Do not store the liquid longer than 10 days.

Side effects

The most common side effects associated with Simpli are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take antacids that contain aluminum or magnesium within 2 hours before or after you take azithromycin. This includes Acid Gone, Aldroxicon, Alternagel, Di-Gel, Gaviscon, Gelusil, Genaton, Maalox, Maldroxal, Milk of Magnesia, Mintox, Mylagen, Mylanta, Pepcid Complete, Rolaids, Rulox, and others. These antacids can make azithromycin less effective when taken at the same time.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking azithromycin and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.

Avoid exposure to sunlight or tanning beds. Simpli can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

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