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Sintedix (Amoxicillin)
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Sintedix

Sintedix is used to treat infections caused by bacteria in different parts of the body. The active ingredient is amoxicillin. This belongs to a group of medicines called penicillin. Antibiotics help treat bacterial infections that may be too strong for the body's immune system to clear. The two drugs are very similar.

Other names for this medication:
Acimox, Almodan, Aloxyn, Amoclen, Amoksicilin, Amopen, Amoram, Amoxi, Amoxicilina, Amoxicillin, Amoxicillinum, Amoxivet, Amoxypen, Amurol, Bimoxan, Bristamox, Cipmox, Clamoxyl, Flemoxin, Flemoxon, Galenamox, Gimalxina, Hidramox, Hydramox, Lupimox, Moxicillin, Novamoxin, Ospamox, Polymox, Robamox, Servamox, Solciclina, Stacillin, Sumox, Utimox, Velamox, Zimox

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Also known as: Amoxicillin

Description

Generic Sintedix is a perfect remedy in struggle against infections caused by certain bacteria. It is also used with other medicines to treat Helicobacter pylori infection and ulcers of the small intestines. Generic Sintedix acts by killing sensitive bacteria. It is a penicillin antibiotic. Generic Sintedix only works against bacteria, it does not treat viral infections. Sintedix is also known as Amoxicillin, Trimox, Actimoxi, Alphamox, AMK, Amoksibos, Amoxiclav Sandoz, Amoxin, Amoksiklav, Amoxibiotic, Amoxicilina, Apo-Amoxi, Bactox, Betalaktam, Cilamox, Curam, Dedoxil, Dispermox, Duomox, Enhancin, Gimalxina, Geramox, Hiconcil, Isimoxin. Generic name of Generic Sintedix is Amoxicillin. Brand name of Generic Sintedix is Sintedix.

Dosage

Children and Adolescents 2 years and older (standard-dose therapy): 45 mg/kg/day PO in divided doses every 12 hours is the standard dose for children with uncomplicated disease that is mild to moderate in severity who do not attend daycare and who have not been treated with an antimicrobial agent in the previous 4 weeks.

Children and Adolescents 2 years and older (high-dose therapy): 80 to 90 mg/kg/day PO in divided doses every 12 hours (Max: 2 g/dose) is recommended for children in areas with high rates of S. pneumoniae resistance (more than 10%, including intermediate- and high-level resistance).

Children younger than 2 years should be treated with Sintedix; clavulanic acid, not Sintedix alone.

Overdose

In case of overdosage, discontinue medication, treat symptomatically, and institute supportive measures as required. If the overdosage is very recent and there is no contraindication, an attempt at emesis or other means of removal of drug from the stomach may be performed. A prospective study of 51 pediatric patients at a poison-control center suggested that overdosages of less than 250 mg/kg of Sintedix are not associated with significant clinical symptoms and do not require gastric emptying.

Interstitial nephritis resulting in oliguric renal failure has been reported in a small number of patients after overdosage with Sintedix.

Crystalluria, in some cases leading to renal failure, has also been reported after Sintedix overdosage in adult and pediatric patients. In case of overdosage, adequate fluid intake and diuresis should be maintained to reduce the risk of Sintedix crystalluria.

Renal impairment appears to be reversible with cessation of drug administration. High blood levels may occur more readily in patients with impaired renal function because of decreased renal clearance of Sintedix. Sintedix may be removed from circulation by hemodialysis.

Storage

Store between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep bottle closed tightly. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Sintedix are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

The possibility of superinfections with mycotic or bacterial pathogens should be kept in mind during therapy. If superinfections occur, Sintedix should be discontinued and appropriate therapy instituted.

A high percentage of patients with mononucleosis who receive ampicillin develop an erythematous skin rash. Thus, ampicillin-class antibiotics should not be administered to patients with mononucleosis.

Prescribing Sintedix in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.

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