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Trichazole (Metronidazole)

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Trichazole is an antibiotic and antiprotozoal medication. It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis.

Other names for this medication:
Acuzole, Aminidazole, Aristogyl, Avidal, Biatron, Biozyl, Buccoval, Cresac, Efloran, Entizol, Flagystatine, Flegyl, Fortagyl, Gnostol, Gynomix, Gynoplix, Medamet, Metral, Metrin, Metrocev, Metronex, Metronide, Metropast, Metrosa, Metrosept, Metrozine, Metsina, Minegyl, Missilor, Nidazol, Noritate, Patryl, Pharmaflex, Protogyl, Rhodogil, Rosaced, Rovamet, Rozagel, Rozamet, Rupezol, Trogyl, Unigyl, Vagizol, Vandazole, Venogyl, Zobacide

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Also known as: Metronidazole


Trichazole (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Trichazole is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.


When repeat courses of the drug are required, it is recommended that an interval of four to six weeks elapse between courses and that the pres- ence of the trichomonad be reconfirmed by appro- priate laboratory measures. Total and differential leukocyte counts should be made before and after re-treatment.


Single oral doses of Trichazole, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Trichazole has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Trichazole overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.


Store Trichazole at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Trichazole out of the reach of children and away from pets.

Side effects

The most common side effects associated with Trichazole are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


To reduce the development of drug-resistant bac- teria and maintain the effectiveness of Trichazole and other antibacterial drugs, Trichazole should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

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African sleeping sickness is a fatal parasitic disease, and all drugs currently in use for treatment have strong liabilities. The results of the cultivation of human mucosal epithelia in vitro are presented and the basic requirements this material should meet are discussed. All dyslipidemic patients displayed higher concentrations of prebeta-1 HDL compared to control individuals. KT3-671, an angiotensin AT1 receptor antagonist, attenuates vascular but not cardiac responses to sympathetic nerve stimulation in pithed rats. This association between Ca entry and norepinephrine release is consistent with the Calcium Hypothesis of transmitter release. Swallowing sound can be used to assess feeding maturation in preterm infants during neonatal intensive care unit follow-up. Postmortem examination revealed a lymphoma of T-cell lineage confined solely to the thoracic cavity, predominantly in lung tissue.

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Formal and informal payments in health care facilities in two Russian cities, Tyumen and Lipetsk. Tetraspecific ligand for tumor-targeted delivery of nanomaterials. No other explanation could be found for his fatal illness, thus suggesting the primary antiphospholipid syndrome (APS). Hyperplastic biliary epithelium was not found within the stent or at the stent ends. The isolated biomolecules are suitable for analysis with different methods that range from electrophoresis and blotting to state-of-the-art procedures based on mass spectrometry (accurate metabolite profiling, shot-gun proteomics) or massive sequencing technologies (transcript analysis). These data suggest that lentivirus-mediated, 2A peptide-based anti-DR5 chimeric antibody expression may have clinical utility as an anticancer treatment and may represent a rational adjuvant therapy in combination with chemotherapy. Laser-assisted transcanalicular dacryocystorhinostomy is a very useful method because it does not cause cutaneous scarring and for it has a low rate of morbidity given that it causes very little surgical traumatism. Problem and methodology in human genetics research in the scope of orthodontics--II. Its use for the POP of the bladder section reduced the consumption of postoperative analgesia.

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The EAT offers a valid and reliable alternative to the TESS-NH and appears to be more suitable for the assessment of the less institutional facilities favoured by Australian aged care services. Ovine pulmonary adenomatosis (OPA) is a naturally occurring contagious lung tumor of sheep which was caused by an exogenous retrovirus of sheep, jaagsiekte retrovirus (JSRV). Similarly, unencapsulated conalbumin also required intracellular processing for presentation to antigen-specific T cells. The objective of this study is to assess the effectiveness of community health workers (CHWs) in Brazil. Cytotrophoblast (CTB) invasion is facilitated from the conversion of plasminogen to plasmin by urokinase plasminogen activator (uPA), regulated by plasminogen activator inhibitor 1 (PAI-1), and may be inhibited in preeclampsia. Cost-effectiveness of balloon kyphoplasty versus standard medical treatment in patients with osteoporotic vertebral compression fracture: a Swedish multicenter randomized controlled trial with 2-year follow-up. What does it mean to be a family physician?: Exploratory study with family medicine residents from 3 countries. Attention deficits and brain morphological changes have been revealed in the HM, but it is unknown whether there are functional connectivity (FC) alterations.

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An electrophysiological investigation of the spatial distribution of attention to colored stimuli in focused and divided attention conditions. Prognosis of surgically treated radiation-induced damage to the intestine. The Nps group was smoothly removed, but the resulting salt of the amine component could not be acylated unless deprotonated with a tertiary base. Here, two kinds of polycyclic aromatic hydrocarbons, pyrene and phenanthrene, were selected to examine their toxic effects on larval behavior of another pufferfish species (T. The presence of significant CSD, particularly among anesthesiology residents, was reconfirmed. This excessive screening may cause physical and psychological harm and may result in unnecessary health care expenditures. In situ hybridization of longitudinal sections of rat incisors revealed a distinct pattern of expression of epimorphin mRNA in the ameloblast layer.

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The SDD regimen consists of colistin, tobramycin and amphotericin B. Draft genome sequence and chemical profiling of Fusarium langsethiae, an emerging producer of type A trichothecenes. The aim of this study was to report the incidence and the management of the problem. Investigation of a filter structure by microbial retention studies: a synthesis and elaboration of prior findings. This greatly improves quality and speed of the automated mapping of particles by SEM prior to EDX analysis. Possible atmospheric consequences of all these results are briefly discussed. AKT (protein kinase B) is implicated in meiotic maturation of porcine oocytes. In this paper, the essential steps of the development of a multi-frequency depth selective device are reviewed. Rickettsia heilongjiangensis is an emerging tick-transmitted human pathogen causing far-Eastern spotted fever. In order to limit the signal effects of extracellular nucleotides, blood cells, plasma and the interior of the vessel walls are provided with nucleotide splitting enzymes: ATP, ADP and AMP are mainly degraded by ectoenzymes present on blood cells, endothelial and on smooth muscle cells, whereas dinucleotides are primarily metabolized by plasma enzymes.

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The agreement between the predicted and measured GDNF concentration gradients was high. Thus, CYR61 promotes primary human fibroblast adhesion, migration, and mitogenesis through integrins alpha(6)beta(1), alpha(v)beta(5), and alpha(v)beta(3), respectively. While the lower-intensity-training runners appeared to benefit psychologically from a training distance of approximately 50 km week-1, high-intensity training had an adverse effect on mood. This review discusses all studies directly related to these effects. Unlike chicken RAD52 and mouse RAD51, no significant difference in mouse RAD52 mRNA level was found among mouse heart, brain, spleen, lung, liver, skeletal muscle, kidney, and testis. The presence of cartilage shards was sought in synovium from the medial and lateral tibiofemoral compartments and the suprapatellar pouch of each patient.

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We identified a new type of ChO attachment cell, which binds to the scolopale cells of these organs, thus behaving like a ligament cell, but on the other hand exhibits all the typical features of a ChO attachment cell and is critical for the correct anchoring of these organs. Comments on origins of enhanced piezoelectric properties in ferroelectrics. Nocardia asteroides keratitis: a case associated with soft contact lens wear. 51 clinically normal iguanas (18 males, 25 females, and 8 juveniles) housed in 3 Florida locations. An apical negative pressure system (EndoVac) results in better debridement at apical 1 mm when compared with side-vented closed ended needle irrigation (Max-I probe). After describing some of the phenomena that influence distending pressure (and its distribution) expressed across pulmonary tissues, we address the pressure costs per unit ventilation and the factors that influence them. To evaluate long-term safety and efficacy of iStent trabecular micro-bypass stent implantation during cataract surgery in patients with primary open-angle, pseudo-exfoliation glaucoma, ocular hypertension, or secondary or post-traumatic glaucoma. By using the X-ray and infrared spectroscopic characteristics of various synthetic analogues and partial structures of lipid A in the dried state, a comparison of these compounds with their natural counterparts was undertaken. Interestingly, further analysis in yeast showed that the transactivation function could be retained even in the presence of dominant-negative p53 tumor mutations that could inhibit wild type p53. Additionally, the existence and characteristics of LORF2 and LORF3 indicated a close relationship with Mardivirus members.

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PTEN and p27 were always highly expressed in non-neoplastic lung whereas Cks1 and Skp2 were not expressed in normal tissue. In line with these observations, cardiac expression of insulin-like growth factor 1 ( IGF1) was significantly induced by both GEN and E2. A kinetic window constricts the T cell receptor repertoire in the thymus. He underwent surgery, but resection was difficult because of strong adhesion. A 58-year-old woman was admitted to our hospital because of renal dysfunction that continued to progress even after withdrawal of cefdinir, the presumed cause of acute renal failure. Sequence, internal homology and high-level expression of the gene for a DNA-(cytosine N4)-methyltransferase, M.Pvu II. Genome of adenovirus and the molecular epidemiology of adenoviral infections. The authors describe herein a 2-month-old infant with NPS who underwent eyelid surgery for bilateral upper eyelid entropion and stromal keratitis. Heartbeat analysis by the time-dependent nonlinear PD2i algorithm is comparatively the superior test.

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The results indicate that informational and energetic masking play substantially different roles in the perception of competing speech messages. Colonic Diverticulitis in a 19-Year-Old Boy With Juvenile Idiopathic Arthritis: Surgical Implications of Chronic Immunosuppression. Comparison of the biochemical properties and levels of HSF1 in the Wistar and Fischer 344 rat strains reveals that HSF1 is constitutively present in an activated DNA-binding state in the adrenals of Fischer 344 rats. Morphometric and molecular characterizations of schistosome populations in Estuaire province Gabon. In addition, different stable isotope dilutions were prepared and are discussed in detail. A sound knowledge of pathophysiology of a disease and clinical pharmacology and therapeutics (CPT) of a drug is required for safe and rational prescribing.

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Although oxidant stress has been implicated in the development of MODS, several recent studies have demonstrated a requirement for NADPH oxidase 2 (NOX2)-derived oxidants in limiting inflammation. Content analysis indicated that their spontaneously reported ongoing strategies were consistent with current theoretical formulations, the strategies differed by area of concern and for real-life versus hypothetical problems, and direct action strategies were related to lower levels of psychologic distress. Myeloid-derived suppressor cells (MDSCs) were initially found to contribute to immunosuppression in tumor patients and have recently been recognized as a subset of innate immune cells that are capable of regulating adaptive immunity. The blood supply of the humerus head is ensured mainly by the a. Precontoured parallel plate fixation of AO/OTA type C distal humerus fractures. Flow injection determination of ketotifen fumarate using PVC membrane selective electrodes. Evolutionary trends in artificial occlusal surfaces of removable dentures. (bluejack oak) trees growing in resource-limited sandhill habitats of the southeastern United States for water and nutrient characteristics. Our data demonstrate that Piezo1 is a novel TFF1 binding protein that is important for TFF1-mediated cell migration and suggest that this interaction may be a therapeutic target in the invasion and metastasis of gastric cancer.

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This study aimed to evaluate the roles of lung function (represented by forced expiratory volume in the first second (FEV1)) and aldosterone as potential mediators of the association of smoking with stroke. Analytical expressions for the temporal variations in the amount of drug released and the size of the unreleased portion of the device are derived. The existence of an organismal ageing dynamics that is invariant across genetic and environmental contexts provides the basis for a new, quantitative framework for evaluating the manner and extent to which specific molecular processes contribute to the aspect of ageing that determines lifespan. Finally, in Leydig cells, PTPN11 supports mitochondrial fusion and the expression of acyl-CoA synthetase (ACSL4) needed for the production of steroids including testosterone, which is required for fertility. By selecting a small fixed region of the detector to collect the XRD signal, the rest of the area was available for collecting the x-ray fluorescence for XAS measurements. Supplementation with soluble Shh-N promoted the proliferation of hematopoietic cells by activating Wnt signaling. Spontaneous activity during the light period was decreased for mice housed with microtitan sheets compared with placebo sheets.

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Pacemapping perfectly matched the spontaneous, incessant arrhythmia. Energy barriers for HET-s prion forming domain amyloid formation. We present a 7-year-old girl with a 2-year history of decelerated growth rate and cushingoidal obesity, upon admission presenting with fixed hypertension. A study was made of the variations in the electrophoretic profile of myofibrillar proteins in the muscles of blue whiting (Micromesistius poutassou R.), horse mackerel (Trachurus trachurus L.) and mackerel (Scomber scombrus L.). Scanning electron microscopic examination of surfaces and margins of restorations. The Stanford Hypnotic Susceptibility Scale, Form C: normative data of a Dutch student sample. The Revised Cambridge Cognitive Examination (CAMCOG-R) is a cognitive screen that cleocin brand has been used to discriminate individuals with dementia from cognitively intact older people. A 33-year-old woman had a cesarean section at term followed by a secondary postpartum hemorrhage due to a ruptured cervicovaginal branch terminating in a large, partially thrombosed hematoma of the cervix.

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Only CLCN3 and CLCN6 messenger RNA were detected by Northern analysis of fetal whole lung tissue. Treatment of lumbosacral radicular pain with epidural steroid injections. These telomere deficiency (rap1t) alleles confer several novel phenotypes. Resistance or emigration: response of the high-alpine plant Eritrichium nanum (L.) Gaudin to the ice age within the Central Alps. Comparative effectiveness of two outreach strategies for cervical cancer screening. We analysed 16S rRNA gene sequence data derived from faecal samples obtained from 728 female twins.

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Effect of low-power nonlinear refraction on laser-beam propagation in InSb. We applied MEMD over EEG channels to extract speech-related brain signal sources, and looked for the intrinsic mode functions which were dominant in the alpha bands. Female BALB/c mice, at ages of 2 and 12 months, were immunized with the 16/6 Id. The in vivo anti-tumor effects of CHM-1-P were evaluated in BALB/c mice inoculated with CT-26 cells orthotopic model. Our proposed ligand-receptor model is in good agreement with previous site-directed mutagenesis experiments. By exposing juvenile and adult frogs to the same dose and strain of Bd, we uncovered ontogenetic differences in susceptibility. These results suggest that ORS is more effective for the prevention of CDDP-induced nephrotoxicity than normal water. We conclude that the high affinity toward cellobiose and low inhibition by biaxin 500 mg generic glucose of these enzymes may offer significant advantages in improving cellulose hydrolysis. These strains were tested by crossing them with transgenic strains expressing Cre in a ubiquitous (beta-actin-Cre) or a cell-specific (Isl1-Cre and En1-Cre) pattern.

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Oribatid communities and heavy metal bioaccumulation in selected species associated with lichens in a heavily contaminated habitat. The specific application involves realistic wave packet calculations of the transient vibrational populations of the Br2(B,vf) fragment produced upon predissociation of the Ne-Br2(B) complex, which is excited to a superposition of overlapping resonance states using different fixed bandwidth pulses where the linear chirps are varied. They also were more likely to be satisfied and less likely to be dissatisfied with care from their pediatric provider and were less likely to place babies in the prone sleep position or feed them water. Inflammatory mediators in allograft malfunction: a new concept in the cyclosporin era. Trauma-related aneurysms may cause sudden death, and this may occur some later time after the trauma.

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The goal of the present study was to quantify context effects in speech recognition using the Basle Sentence Understanding Test. These natural killer T cells play important roles in anti-tumor immunity, transplantation immunity, allergy, autoimmunity and microbial immunity. Epidemiological observations of consanguinity and retinoblastoma in Arabia. Dietary protein sensitivity: is it an important risk factor for persistent diarrhea?. Identification of novel blood group-reactive monoclonal antibodies cytotoxic to human acinar cells but not islets. Amoxicillin, or zithromax syrup spc vancomycin or teicoplanin are recommended for procedures under general anaesthesia. JNK inhibitor Sp600125 attenuated DS/Cu/Dox-induced apoptosis and suppressed DS/Cu/Dox-induced protein expression in JNK/c-jun pathway. Although intramedullary TB combined with abscess is clinically rare, it should be taken into consideration when patients present with intramedullary space-occupying lesions with TB lesions elsewhere.

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The hypertensive patients have distinct microRNAs expression Profile. Comparisons of each gabapentin enacarbil dose with placebo were performed using three different statistical methodologies: last observation carried forward, baseline observation carried forward, and mixed-effect model for repeated measures. Customer Satisfaction, Taking Care of the Loved Ones in a can i drink alcohol while taking levaquin Time of Crisis. Woolhouse reported by 1721 that he had performed 36 congenital cataract surgeries, with the youngest patient being 18 months of age. Anticancer benefits of early versus late use of rapamycin in a rat model of urothelial carcinoma. The highest values were observed in 6-12-month-old goats in all the breeds, whereafter they decreased to relatively constant adult levels. The present study uses immunohistochemical methods, with a polyclonal antiserum directed against the human form of CRF, to determine the distribution of this peptide in non-colchicine-treated monkeys (Saimiri sciureus). Although obviously malignant, a majority of the cells expressed well-differentiated cilia with terminal bar formation. The loss of response to antidepressant drugs is not an uncommon phenomenon.

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Adeno-associated virus-2 (AAV) is known to have onco-suppressive properties against DNA tumor viruses. Commissions of audit in Australia: health system privatisation directives and civil conscription protections. This report highlights the relevance of the histopathological diagnosis in patients with a history of bronchogenic carcinoma and suspicion of tumor recurrence. We conclude that adenoviral vectors can reprogram human fibroblasts to pluripotent stem cells for use in individualized cell therapy without the risk for viral or oncogene incorporation. Sugar in its pure form, or incorporated into a paste containing an adhesive hydropolymer (gum), is a non-toxic treatment for a variety of wounds. Data were collected using a demographics questionnaire developed by the investigator and the Safe Sex Behavior Questionnaire (SSBQ). Transient and continuous expression of NADPH diaphorase in different neuronal populations of developing rat spinal cord. The magnetic susceptibility of tissue can be determined in gradient echo MRI by deconvolving the local magnetic field with the magnetic field generated by a unit dipole.

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