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Uroquin (Norfloxacin)
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Uroquin

Uroquin is a fluoroquinolone antibiotic. Uroquin works by blocking DNA gyrase enzyme, which is responsible for production and repair of bacterial DNA. Blocking of DNA gyrase leads to bacteria death and prevents worsening of infection.

Other names for this medication:
Apiflox, Asudufe, Barazan, Baxicin, Bexinor, Chibroxol, Danilon, Effectsal, Floxamed, Floxamicin, Floxatrat, Gyrablock, Lemorcan, Lexiflox, Microxin, Nalion, Noflo, Norax, Noraxin, Norfen, Norflodal, Norflogen, Norflohexal, Norflok, Norflomax, Norilet, Noroxine, Parcetin, Respexil, Senro, Sofasin, Taflox, Theanorf, Uricin, Uritracin, Uroflox, Urofos, Uroquin, Utibid, Uticina, Utinor, Vetamol, Wenflox, Xaflor, Xasmun, Zoroxin

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Terramycin, Myambutol, Rulide, Chloromycetin, Keflex, Biaxin, Avelox, Zithromax, Floxin, Sumycin

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Also known as: Norfloxacin

Description

Uroquin comes as a tablet to take by mouth. It is usually taken twice a day for 3 to 28 days. The length of treatment depends on the type of infection being treated. Your doctor will tell you how long to take Uroquin. Take Uroquin at around the same times every day and try to space your doses 12 hours apart. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Uroquin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Take Uroquin at least 1 hour before or 2 hours after meals or after drinking milk or eating dairy products.

Swallow the tablets with a full glass of water.

You should begin to feel better during the first few days of your treatment with Uroquin. If your symptoms do not improve or if they get worse, call your doctor.

Take Uroquin until you finish the prescription, even if you feel better. Do not stop taking Uroquin without talking to your doctor unless you experience certain serious side effects listed in the IMPORTANT WARNING or SIDE EFFECT sections. If you stop taking Uroquin too soon or if you skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

Uroquin is also sometimes used to treat certain infections of the stomach and intestines. Talk to your doctor about the risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Dosage

Before taking Uroquin tell your doctor and pharmacist if you are allergic or have had a severe reaction to Uroquin; other quinolone or fluoroquinolone antibiotics such as ciprofloxacin (Cipro), gatifloxacin (Tequin) (not available in the U.S.), gemifloxacin (Factive), levofloxacin (Levaquin), lomefloxacin (Maxaquin) (not available in the U.S.), moxifloxacin (Avelox), nalidixic acid (NegGram), ofloxacin (Floxin), and sparfloxacin (Zagam) (not available in the U.S.), or any other medications.

Tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, herbal products, and nutritional supplements you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: other antibiotics; anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); certain antidepressants; antipsychotics (medications to treat mental illness); caffeine or medications that contain caffeine (Excedrin, NoDoz, Vivarin, others); cisapride (Propulsid) (not available in the U.S.); clozapine (Clozaril, Fazaclo); cyclosporine (Gengraf, Neoral, Sandimmune); diuretics ('water pills'); erythromycin (E.E.S, E-Mycin, Erythrocin, others); glyburide (DiaBeta, in Glucovance, Micronase, others); certain medications for irregular heartbeat such as amiodarone (Cordarone), procainamide (Procanbid), quinidine, and sotalol (Betapace, Betapace AF, Sorine); nitrofurantoin (Furadantin, Macrobid, Macrodantin); probenecid (in Col-Probenecid, Probalan); nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin, others) and naproxen (Aleve, Naprosyn, others); ropinirole (Requip); tacrine (Cognex); theophylline (Elixophyllin, Theo-24, Uniphyl, others); and tizanidine (Zanaflex). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

If you are taking antacids containing aluminum hydroxide or magnesium hydroxide (Maalox, Mylanta, Tums, others), didanosine (Videx) sucralfate (Carafate), or supplements or multivitamins that contain iron or zinc, take these medications 2 hours before or 2 hours after you take Uroquin.

Tell your doctor if you or anyone in your family has or has ever had a prolonged QT interval (a rare heart problem that may cause irregular heartbeat, fainting or sudden death) or an irregular heartbeat and if you have or have ever had nerve problems, a low level of potassium in your blood, a slow heartbeat, chest pain, seizures, myasthenia gravis (condition that causes weakness of certain muscles), cerebral arteriosclerosis (narrowing of blood vessels in or near the brain that can lead to stroke or mini-stroke), or glucose-6-phosphate dehydrogenase (G-6PD) deficiency (an inherited blood disorder).

Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking Uroquin, call your doctor.

You should know that this medication may cause dizziness, lightheadedness, and tiredness. Do not drive a car, operate machinery, or participate in activities requiring alertness and coordination until you know how Uroquin affects you.

Plan to avoid unnecessary or prolonged exposure to sunlight or ultraviolet light (tanning beds and sunlamps) and to wear protective clothing, sunglasses, and sunscreen. Uroquin may make your skin sensitive to sunlight or ultraviolet light. If your skin becomes reddened, swollen, or blistered, call your doctor.

Overdose

If you overdose Generic Uroquin and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep bottle closed tightly. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Uroquin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You may be taking certain other medicines that should not be taken at the same time as norfloxacin. Avoid taking the following medicines within 2 hours before or after you take norfloxacin. These other medicines can make norfloxacin much less effective when taken at the same time: antacids that contain magnesium or aluminum (such as Maalox, Mylanta, or Rolaids); the ulcer medicine sucralfate (Carafate); didanosine (Videx) powder or chewable tablets; or vitamin or mineral supplements that contain iron or zinc.

Avoid caffeine while you are taking norfloxacin, because the medication can make the effects of caffeine stronger.

Avoid exposure to sunlight or tanning beds. Norfloxacin can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Call your doctor if you have severe burning, redness, itching, rash, or swelling after being in the sun.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking norfloxacin and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.

Norfloxacin may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

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