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Zeclar (Clarithromycin)
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Zeclar

Zeclar is used in various infections on the body like the skin, soft tissue, chest and stomach infections. It contains clarithromycin which is an antibiotic medicine. It acts by stopping the multiplication of bacteria.

Other names for this medication:
Althromicin, Bacterfin, Biotclarcin, Clabact, Clacee, Clacine, Clarimed, Clarimycin, Clarocin, Clarogen, Claromac, Claron, Clarosip, Claxid, Cleanomisin, Cleron, Clormicin, Eliben, Eracid, Ezumycin, Fromilid, Infex, Italclar, Kailasa, Klarifor, Klarigen, Klariger, Klarith, Klazidem, Klerimed, Klonacid, Kofron, Laromin, Lekoklar, Lyoclar, Macrol, Macromicina, Monozeclar, Odycin, Onexid, Rocin, Rodizim, Uniklar, Xylar

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Also known as: Clarithromycin

Description

Zeclar (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac / Claribid) is used to treat many different types of bacterial infections affecting the skin and respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis (inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.

It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.

It also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Zeclar works by stopping the growth of or killing sensitive bacteria by interfering with their protein synthesis.

Dosage

The recommended daily dosage is 15 mg/kg/day divided every 12 hours for 10 days (up to the adult dose). Refer to dosage regimens for mycobacterial infections in pediatric patients for additional dosage information.

For the treatment of disseminated infection due to Mycobacterium avium complex (MAC), Zeclar Filmtab and Zeclar Granules are recommended as the primary agents. Zeclar Filmtab and Zeclar Granules should be used in combination with other antimycobacterial drugs (e.g. ethambutol) that have shown in vitro activity against MAC or clinical benefit in MAC treatment.

For treatment and prophylaxis of mycobacterial infections in adults, the recommended dose of Zeclar is 500 mg every 12 hours.

For treatment and prophylaxis of mycobacterial infections in pediatric patients, the recommended dose is 7.5 mg/kg every 12 hours up to 500 mg every 12 hours.

Zeclar therapy should continue if clinical response is observed. Zeclar can be discontinued when the patient is considered at low risk of disseminated infection.

Overdose

Overdose symptoms may include severe stomach pain, nausea, vomiting, or diarrhea.

Storage

Store Zeclar at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Zeclar out of the reach of children and away from pets.

Side effects

The most common side effects associated with Zeclar are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Discontinue immediately if hepatitis or severe hypersensitivity reactions occurs. Severe renal impairment. Proarrhythmic conditions (eg, hypokalemia, hypomagnesemia, bradycardia); avoid. Myasthenia gravis. History of porphyria; avoid concomitant ranitidine bismuth citrate. Elderly. Pregnancy (Cat.C): usually not recommended. Nursing mothers.

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